Prof. Dr. rer. nat. Manfred Blessing
FB 04 - Universitätsmedizin, Johannes Gutenberg-Universität Mainz
Schramm, Christoph; Herz, Udo; Podlech, Jürgen et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - TGF-b Regulates Airway Responses Via T CellsBethesda, Md.: American Assoc. of Immunologists 2003 S. 1313 - 1319
Schramm, C.; Protschka, M.; Köhler, H.H. et al.
INFLAMMATION-IMMUNITY-MEDIATORS - Impairment of TGF-b signaling in T cells increases susceptibility to experimental autoimmune hepatitis in miceAmerican journal of physiology. Bd. 47. H. 3. Bethesda, Md.: Soc. 2003
Amendt, C.; Mann, A.; Schirmacher, P. et al.
Research Articles - Resistance of keratinocytes to TGFb-mediated growth restriction and apoptosis induction accelerates re-epithelialization in skin wounds.Journal of cell science. Bd. 115. H. 10. Cambridge: Cambridge Biologists 2002 S. 2189 - 2198
Becker, Christoph; Wirtz, Stefan; Ma, Xiaojing et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - Regulation of IL-12 p40 Promoter Activity in Primary Human Monocytes: Roles of NF-kB, CCAAT-Enhancer-Binding Protein b, and PU.1 and Identification of a Novel Repressor Element (GA-12) That Responds to IL-4 andThe journal of immunology. official journal of the American Association of Immunologists. Bd. 167. H. 5. Bethesda, Md.: American Assoc. of Immunologists 2001 S. 2608 - 2618
Mann, Amrit; Breuhahn, Kai; Schirmacher, Peter et al.
Keratinocyte-Derived Granulocyte-Macrophage Colony Stimulating Factor Accelerates Wound Healing: Stimulation of Keratinocyte Proliferation, Granulation Tissue Formation, and VascularizationThe journal of investigative dermatology. official journal of the Society for Investigative Dermatology and the European Society for Dermatological Research. Bd. 117. H. 6. New York, NY: Nature Publishing Group 2001 S. 1382 - 1390
Kanzler, Stephan; Meyer, Erik; Lohse, Ansgar Wilhelm et al.
ORIGINAL PAPERS - Hepatocellular expression of a dominant-negative mutant TGF-b type II receptor accelerates chemically induced hepatocarcinogenesisOncogene. an international journal. Bd. 20. H. 36. Basingstoke: Nature Publ. Group 2001 S. 5015 - 5024
Özbek, Suat; Peters, Malte; Breuhahn, Kai et al.
ORIGINAL PAPERS - The designer cytokine hyper-IL-6 mediates growth inhibition and GM - CSF-dependent rejection of B16 melanoma cellsOncogene. an international journal. Bd. 20. H. 8. Basingstoke: Nature Publ. Group 2001 S. 972 - 979
Wach, S.; Schirmacher, P.; Protschka, M. et al.
Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses skin tumor formation by induction of apoptosis and downregulation of fos-jun family membersOncogene. an international journal. Bd. 20. H. 53. Basingstoke: Nature Publ. Group 2001 S. 7761 - 7769
Mann, Amrit; Breuhahn, Kai; Schirmacher, Peter et al.
Tumor Biology - Up- and Down-Regulation of Granulocyte-Macrophage-Colony Stimulating Factor Activity in Murine Skin Increase Susceptibility to Skin Carcinogenesis by Independent Mechanisms.Cancer research. an official organ of the American Association for Cancer Research. Bd. 61. H. 5. Birmingham, Ala. [u.a.]: AACR 2001 S. 2311 - 2319
Breuhahn, Kai; Mann, Amrit; Müller, Gabriele et al.
Articles - Epidermal Overexpression of Granulocyte-Macrophage Colony- Stimulating Factor Induces Both Keratinocyte Proliferation and ApoptosisCell growth & differentiation. CG&D ; the molecular biology journal of the American Association for Cancer Research. Bd. 11. H. 2. Baltimore, Md.: Waverly Press 2000 S. 111 - 122
Wirtz, Stefan; Finotto, Susetta; Kanzler, Stephan et al.
CUTTING EDGE - Cutting Edge: Chronic Intestinal Inflammation in STAT-4 Transgenic Mice: Characterization of Disease and Adoptive Transfer by TNF- Plus IFN-g-Producing CD4+ T Cells That Respond to Bacterial AntigensThe journal of immunology. official journal of the American Association of Immunologists. Bd. 162. H. 4. Bethesda, Md.: American Assoc. of Immunologists 1999 S. 1884 - 1888
Kanzler, S.; Lohse, A.W.; Keil, A. et al.
LIVER AND BILIARY TRACT - TGF-b1 in liver fibrosis: An inducible transgenic mouse model to study liver fibrogenesisAmerican journal of physiology. Bd. 39. H. 4. Bethesda, Md.: Soc. 1999
Amendt, C.; Schirmacher, P.; Weber, H. et al.
Expression of a dominant negative type II TGF-b receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma developmentOncogene. an international journal. Bd. 17. H. 1. Basingstoke: Nature Publ. Group 1998 S. 25 - 34
Schirmacher, Peter; Peters, Malte; Ciliberto, Gennaro et al.
Hepatocellular Hyperplasia, Plasmacytoma Formation, and Extramedullary Hematopoiesis in Interleukin (IL)-6-Soluble IL-6 Receptor Double-Transgenic MiceThe American journal of pathology. cellular and molecular biology of disease ; official publication of the American Society for Investigative Pathology. Bd. 153. H. 2. Bethesda, Md.: American Society for Investigative Pathology 1998 S. 639 - 648
Kaiser, Sibylle; Shirmacher, Peter; Philipp, Armin et al.
REGULAR ARTICLES - Induction of Bone Morphogenetic Protein-6 in Skin Wounds. Delayed Reepitheliazation and Scar Formation in BMP-6 Overexpressing Transgenic MiceThe journal of investigative dermatology. official journal of the Society for Investigative Dermatology and the European Society for Dermatological Research. Bd. 111. H. 6. New York, NY: Nature Publishing Group 1998 S. 1145 - 1152
Jahnen-Dechent, Willi; Schinke, Thorsten; Trindl, Andreas et al.
Cloning and targeted deletion of the mouse fetuin gene.The journal of biological chemistry. JBC. Bd. 272. H. 50. Bethesda, Md.: ASBMB 1997 S. 31496 - 31503
Peters, M.; Odenthal, M.; Schirmacher, P. et al.
Soluble IL-6 receptor leads to a paracrine modulation of the IL-6- induced hepatic acute phase response in double transgenic miceJ Innumol. Bd. J Innumol. 1997 S. 1474-81
Blessing, M.; Schirmacher, P.; Kaiser, S.
Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: Inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesionsThe journal of cell biology. JCB. Bd. 135. H. 1. New York, NY: Rockefeller Univ. Press 1996 S. 227 - 240
Labosky, Patricia A.; Winnier, Glenn E.; Sasaki, Hiroshi et al.
Short Communication: The Chromosomal Mapping of Four Genes Encoding Winged Helix Proteins Expressed Early in Mouse DevelopmentGenomics. internat. journal of gene mapping and nucleotide sequencing ; emphasizing analyses of the human and other complex genomes. Bd. 34. H. 2. San Diego, Calif. [u.a.]: Elsevier 1996 S. 241 - 245
Winnier, Glenn; Blessing, Manfred; Labosky, Patricia A. et al.
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouseGenes & development. a journal of celluar and molecular biology. Bd. 9. H. 17. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press 1995 S. 2105 - 2116
Blessing, Manfred; Nanney, Lillian B.; King, Lloyd E. et al.
Chemical Skin Carcinogenesis is Prevented in Mice by the Induced Expression of a TGF-b Related TransgeneTeratogenesis, carcinogenesis, and mutagenesis. Bd. 15. H. 1. New York, NY: Liss 1995 S. 11 - 22
Megosh, Louis; Gilmour, Susan K.; Rosson, Dan et al.
Increased Frequency of Spontaneous Skin Tumors in Transgenic Mice Which Overexpress Ornithine DecarboxylaseCancer research. an official organ of the American Association for Cancer Research. Bd. 55. H. 19. Birmingham, Ala. [u.a.]: AACR 1995 S. 4205 - 4209
Casatorres, José; Navarro, J.Manuel; Blessing, Manfred et al.
Analysis of the control of expression and tissue specificity of the keratin 5 gene, characteristic of basal keratinocytes. Fundamental role of an AP-1 elementThe journal of biological chemistry. JBC. Bd. 269. H. 32. Bethesda, Md.: ASBMB 1994 S. 20489 - 20496
Hogan, B.L.M.; Blessing, Manfred; Winnier, G.E. et al.
Growth factors in development: The role of TGF-b related polypeptide signalling molecules in embryogenesisDevelopment. H. Supplement. Cambridge: The Company of Biologists 1994 S. 53 - 60
Wall, N.A.; Blessing, M.; Wright, C.V.E. et al.
Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6).The journal of cell biology. JCB. Bd. 120. H. 2. New York, NY: Rockefeller Univ. Press 1993 S. 493 - 502