CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - TGF-b Regulates Airway Responses Via T Cells - Christoph Schramm; Udo Herz; Jürgen Podlech; Martina Protschka; Susetta Finotto; Matthias J. Reddehase; Heinz Köhler; Peter R. Galle; Ansgar W. Lohse; Manfred Blessing (American Assoc. of Immunologists, 2003)

INFLAMMATION-IMMUNITY-MEDIATORS - Impairment of TGF-b signaling in T cells increases susceptibility to experimental autoimmune hepatitis in mice - C. Schramm; M. Protschka; H.H. Köhler; J. Podlech; M.J. Reddehase; P. Schirmacher; P.R. Galle; A.W. Lohse; M. Blessing (American journal of physiology, 2003)

Research Articles - Resistance of keratinocytes to TGFb-mediated growth restriction and apoptosis induction accelerates re-epithelialization in skin wounds. - C. Amendt; A. Mann; P. Schirmacher; M. Blessing (Journal of cell science, 2002)

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - Regulation of IL-12 p40 Promoter Activity in Primary Human Monocytes: Roles of NF-kB, CCAAT-Enhancer-Binding Protein b, and PU.1 and Identification of a Novel Repressor Element (GA-12) That Responds to IL-4 and - Christoph Becker; Stefan Wirtz; Xiaojing Ma; Manfred Blessing; Peter R. Galle; Markus F. Neurath (The journal of immunology. official journal of the American Association of Immunologists, 2001)

Keratinocyte-Derived Granulocyte-Macrophage Colony Stimulating Factor Accelerates Wound Healing: Stimulation of Keratinocyte Proliferation, Granulation Tissue Formation, and Vascularization - Amrit Mann; Kai Breuhahn; Peter Schirmacher; Manfred Blessing (The journal of investigative dermatology. official journal of the Society for Investigative Dermatology and the European Society for Dermatological Research, 2001)

ORIGINAL PAPERS - Hepatocellular expression of a dominant-negative mutant TGF-b type II receptor accelerates chemically induced hepatocarcinogenesis - Stephan Kanzler; Erik Meyer; Ansgar Wilhelm Lohse; Peter Schirmacher; Jürgen Henninger; Peter Robert Galle; Manfred Blessing (Oncogene. an international journal, 2001)

ORIGINAL PAPERS - The designer cytokine hyper-IL-6 mediates growth inhibition and GM - CSF-dependent rejection of B16 melanoma cells - Suat Özbek; Malte Peters; Kai Breuhahn; Amrit Mann; Manfred Blessing; Martina Fischer; Peter Schirmacher; Andrzej Mackiewicz; Stefan Rose-John (Oncogene. an international journal, 2001)

Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses skin tumor formation by induction of apoptosis and downregulation of fos-jun family members - S. Wach; P. Schirmacher; M. Protschka; M. Blessing (Oncogene. an international journal, 2001)

Tumor Biology - Up- and Down-Regulation of Granulocyte-Macrophage-Colony Stimulating Factor Activity in Murine Skin Increase Susceptibility to Skin Carcinogenesis by Independent Mechanisms. - Amrit Mann; Kai Breuhahn; Peter Schirmacher; Arnd Wilhelmi; Carsten Beyer; Andrea Rosenau; Suat Özbek; Stefan Rose-John; Manfred Blessing (Cancer research. an official organ of the American Association for Cancer Research, 2001)

Articles - Epidermal Overexpression of Granulocyte-Macrophage Colony- Stimulating Factor Induces Both Keratinocyte Proliferation and Apoptosis - Kai Breuhahn; Amrit Mann; Gabriele Müller; Arnd Wilhelmi; Peter Schirmacher; Alexander Enk; Manfred Blessing (Cell growth & differentiation. CG&D ; the molecular biology journal of the American Association for Cancer Research, 2000)

CUTTING EDGE - Cutting Edge: Chronic Intestinal Inflammation in STAT-4 Transgenic Mice: Characterization of Disease and Adoptive Transfer by TNF- Plus IFN-g-Producing CD4+ T Cells That Respond to Bacterial Antigens - Stefan Wirtz; Susetta Finotto; Stephan Kanzler; Ansgar W. Lohse; Manfred Blessing; Hans A. Lehr; Peter R. Galle; Markus F. Neurath (The journal of immunology. official journal of the American Association of Immunologists, 1999)

LIVER AND BILIARY TRACT - TGF-b1 in liver fibrosis: An inducible transgenic mouse model to study liver fibrogenesis - S. Kanzler; A.W. Lohse; A. Keil; J. Henninger; H.P. Dienes; P. Schirmacher; S. Rose-John; K.H.Meyer zum Büschenfelde; M. Blessing (American journal of physiology, 1999)

Expression of a dominant negative type II TGF-b receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development - C. Amendt; P. Schirmacher; H. Weber; M. Blessing (Oncogene. an international journal, 1998)

Hepatocellular Hyperplasia, Plasmacytoma Formation, and Extramedullary Hematopoiesis in Interleukin (IL)-6-Soluble IL-6 Receptor Double-Transgenic Mice - Peter Schirmacher; Malte Peters; Gennaro Ciliberto; Manfred Blessing; Johannes Lotz; Karl-Herrmann Meyer zum Büschenfelde; Stefan Rose John (The American journal of pathology. cellular and molecular biology of disease ; official publication of the American Society for Investigative Pathology, 1998)

REGULAR ARTICLES - Induction of Bone Morphogenetic Protein-6 in Skin Wounds. Delayed Reepitheliazation and Scar Formation in BMP-6 Overexpressing Transgenic Mice - Sibylle Kaiser; Peter Shirmacher; Armin Philipp; Martina Protschka; Ingrid Moll; Karin Nicol; Manfred Blessing (The journal of investigative dermatology. official journal of the Society for Investigative Dermatology and the European Society for Dermatological Research, 1998)

Cloning and targeted deletion of the mouse fetuin gene. - Willi Jahnen-Dechent; Thorsten Schinke; Andreas Trindl; Werner Müller-Esterl; Fred Sablitzky; Sibylle Kaiser; Manfred Blessing (The journal of biological chemistry. JBC, 1997)

Soluble IL-6 receptor leads to a paracrine modulation of the IL-6- induced hepatic acute phase response in double transgenic mice - M. Peters; M. Odenthal; P. Schirmacher; M. Blessing; E. Fattori; G. Ciliberto; K. H. Meyer zum Büschenfelde; S. Rose - John (J Innumol, 1997)

Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: Inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions - M. Blessing; P. Schirmacher; S. Kaiser (The journal of cell biology. JCB, 1996)

Short Communication: The Chromosomal Mapping of Four Genes Encoding Winged Helix Proteins Expressed Early in Mouse Development - Patricia A. Labosky; Glenn E. Winnier; Hiroshi Sasaki; Manfred Blessing; Brigid L.M. Hogan (Genomics. internat. journal of gene mapping and nucleotide sequencing ; emphasizing analyses of the human and other complex genomes, 1996)

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse - Glenn Winnier; Manfred Blessing; Patricia A. Labosky; Brigid L.M. Hogan (Genes & development. a journal of celluar and molecular biology, 1995)

Chemical Skin Carcinogenesis is Prevented in Mice by the Induced Expression of a TGF-b Related Transgene - Manfred Blessing; Lillian B. Nanney; Lloyd E. King; Brigid L.M. Hogan (Teratogenesis, carcinogenesis, and mutagenesis, 1995)

Increased Frequency of Spontaneous Skin Tumors in Transgenic Mice Which Overexpress Ornithine Decarboxylase - Louis Megosh; Susan K. Gilmour; Dan Rosson; Aléjandro Peralta Soler; Manfred Blessing; Janet A. Sawicki; Thomas G. O'Brien (Cancer research. an official organ of the American Association for Cancer Research, 1995)

Analysis of the control of expression and tissue specificity of the keratin 5 gene, characteristic of basal keratinocytes. Fundamental role of an AP-1 element - José Casatorres; J.Manuel Navarro; Manfred Blessing; José L. Jorcano (The journal of biological chemistry. JBC, 1994)

Growth factors in development: The role of TGF-b related polypeptide signalling molecules in embryogenesis - B.L.M. Hogan; Manfred Blessing; G.E. Winnier; N. Suzuki; C.M. Jones (Development, 1994)

Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6). - N.A. Wall; M. Blessing; C.V.E. Wright; B.L.M. Hogan (The journal of cell biology. JCB, 1993)

Ectopic synthesis of epidermal cytokeratins in pancreatic islet cells of transgenic mice interferes with cytoskeletal order and insulin production. - M. Blessing; U. Rüther; W.W. Franke (The journal of cell biology. JCB, 1993)

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation - S. Werner; W. Weinberg; X. Liao; K.G. Peters; M. Blessing; S.H. Yuspa; R.L. Weiner; L.T. Williams (The EMBO journal, 1993)

Transgenic mice as a model to study the role of TGF-b-related molecules in hair follicles - Manfred Blessing; Lillian B. Nanney; Lloyd E. King; C.Michael Jones; Brigid L.M. Hogan (Genes & development. a journal of celluar and molecular biology, 1993)

Mapping of bovine cytokeratin sequences to four different sites on three chromosomes - R. Fries; D. W. Threadgill; R. Hediger; A. Gunawardana; M. Blessing; J. L. Jorcano; G. Stranzinger; J. E. Womack (Cytogenet Cell Genet, 1991)

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter - B. Bailleul; M. A. Surani; S. White; S. C. Barton; K. Brown; M. Blessing; J. Jorcano; A. Balmain (Cell, 1990)

Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes - M. Blessing; J. L. Jorcano; W. W. Franke (EMBO Journal, 1989)

Differentially expressed bovine cytokeratin genes. Analysis of gene linkage and evolutionary conservation of 5´-upstream sequences - M. Blessing; H. Zentgraf; J. L. Jorcano (EMBO Journal, 1987)

Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins - M. E. Lehnert; J. L. Jorcano; H. Zentgraf; M. Blessing; J. K. Franz; W. W. Franke (EMBO Journal, 1984)