Prof. Dr. rer. nat. Manfred Blessing - Publikationen

Schramm, Christoph; Herz, Udo; Podlech, Jürgen et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - TGF-b Regulates Airway Responses Via T Cells
Bethesda, Md.: American Assoc. of Immunologists 2003 S. 1313 - 1319

Schramm, C.; Protschka, M.; Köhler, H.H. et al.
INFLAMMATION-IMMUNITY-MEDIATORS - Impairment of TGF-b signaling in T cells increases susceptibility to experimental autoimmune hepatitis in mice
American journal of physiology. Bd. 47. H. 3. Bethesda, Md.: Soc. 2003

Amendt, C.; Mann, A.; Schirmacher, P. et al.
Research Articles - Resistance of keratinocytes to TGFb-mediated growth restriction and apoptosis induction accelerates re-epithelialization in skin wounds.
Journal of cell science. Bd. 115. H. 10. Cambridge: Cambridge Biologists 2002 S. 2189 - 2198

Becker, Christoph; Wirtz, Stefan; Ma, Xiaojing et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - Regulation of IL-12 p40 Promoter Activity in Primary Human Monocytes: Roles of NF-kB, CCAAT-Enhancer-Binding Protein b, and PU.1 and Identification of a Novel Repressor Element (GA-12) That Responds to IL-4 and
The journal of immunology. official journal of the American Association of Immunologists. Bd. 167. H. 5. Bethesda, Md.: American Assoc. of Immunologists 2001 S. 2608 - 2618

Mann, Amrit; Breuhahn, Kai; Schirmacher, Peter et al.
Keratinocyte-Derived Granulocyte-Macrophage Colony Stimulating Factor Accelerates Wound Healing: Stimulation of Keratinocyte Proliferation, Granulation Tissue Formation, and Vascularization
The journal of investigative dermatology. official journal of the Society for Investigative Dermatology and the European Society for Dermatological Research. Bd. 117. H. 6. New York, NY: Nature Publishing Group 2001 S. 1382 - 1390

Kanzler, Stephan; Meyer, Erik; Lohse, Ansgar Wilhelm et al.
ORIGINAL PAPERS - Hepatocellular expression of a dominant-negative mutant TGF-b type II receptor accelerates chemically induced hepatocarcinogenesis
Oncogene. an international journal. Bd. 20. H. 36. Basingstoke: Nature Publ. Group 2001 S. 5015 - 5024

Özbek, Suat; Peters, Malte; Breuhahn, Kai et al.
ORIGINAL PAPERS - The designer cytokine hyper-IL-6 mediates growth inhibition and GM - CSF-dependent rejection of B16 melanoma cells
Oncogene. an international journal. Bd. 20. H. 8. Basingstoke: Nature Publ. Group 2001 S. 972 - 979

Wach, S.; Schirmacher, P.; Protschka, M. et al.
Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses skin tumor formation by induction of apoptosis and downregulation of fos-jun family members
Oncogene. an international journal. Bd. 20. H. 53. Basingstoke: Nature Publ. Group 2001 S. 7761 - 7769

Mann, Amrit; Breuhahn, Kai; Schirmacher, Peter et al.
Tumor Biology - Up- and Down-Regulation of Granulocyte-Macrophage-Colony Stimulating Factor Activity in Murine Skin Increase Susceptibility to Skin Carcinogenesis by Independent Mechanisms.
Cancer research. an official organ of the American Association for Cancer Research. Bd. 61. H. 5. Birmingham, Ala. [u.a.]: AACR 2001 S. 2311 - 2319

Breuhahn, Kai; Mann, Amrit; Müller, Gabriele et al.
Articles - Epidermal Overexpression of Granulocyte-Macrophage Colony- Stimulating Factor Induces Both Keratinocyte Proliferation and Apoptosis
Cell growth & differentiation. CG&D ; the molecular biology journal of the American Association for Cancer Research. Bd. 11. H. 2. Baltimore, Md.: Waverly Press 2000 S. 111 - 122

Wirtz, Stefan; Finotto, Susetta; Kanzler, Stephan et al.
CUTTING EDGE - Cutting Edge: Chronic Intestinal Inflammation in STAT-4 Transgenic Mice: Characterization of Disease and Adoptive Transfer by TNF- Plus IFN-g-Producing CD4+ T Cells That Respond to Bacterial Antigens
The journal of immunology. official journal of the American Association of Immunologists. Bd. 162. H. 4. Bethesda, Md.: American Assoc. of Immunologists 1999 S. 1884 - 1888

Kanzler, S.; Lohse, A.W.; Keil, A. et al.
LIVER AND BILIARY TRACT - TGF-b1 in liver fibrosis: An inducible transgenic mouse model to study liver fibrogenesis
American journal of physiology. Bd. 39. H. 4. Bethesda, Md.: Soc. 1999

Amendt, C.; Schirmacher, P.; Weber, H. et al.
Expression of a dominant negative type II TGF-b receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development
Oncogene. an international journal. Bd. 17. H. 1. Basingstoke: Nature Publ. Group 1998 S. 25 - 34

Schirmacher, Peter; Peters, Malte; Ciliberto, Gennaro et al.
Hepatocellular Hyperplasia, Plasmacytoma Formation, and Extramedullary Hematopoiesis in Interleukin (IL)-6-Soluble IL-6 Receptor Double-Transgenic Mice
The American journal of pathology. cellular and molecular biology of disease ; official publication of the American Society for Investigative Pathology. Bd. 153. H. 2. Bethesda, Md.: American Society for Investigative Pathology 1998 S. 639 - 648

Kaiser, Sibylle; Shirmacher, Peter; Philipp, Armin et al.
REGULAR ARTICLES - Induction of Bone Morphogenetic Protein-6 in Skin Wounds. Delayed Reepitheliazation and Scar Formation in BMP-6 Overexpressing Transgenic Mice
The journal of investigative dermatology. official journal of the Society for Investigative Dermatology and the European Society for Dermatological Research. Bd. 111. H. 6. New York, NY: Nature Publishing Group 1998 S. 1145 - 1152

Jahnen-Dechent, Willi; Schinke, Thorsten; Trindl, Andreas et al.
Cloning and targeted deletion of the mouse fetuin gene.
The journal of biological chemistry. JBC. Bd. 272. H. 50. Bethesda, Md.: ASBMB 1997 S. 31496 - 31503

Peters, M.; Odenthal, M.; Schirmacher, P. et al.
Soluble IL-6 receptor leads to a paracrine modulation of the IL-6- induced hepatic acute phase response in double transgenic mice
J Innumol. Bd. J Innumol. 1997 S. 1474-81

Blessing, M.; Schirmacher, P.; Kaiser, S.
Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: Inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions
The journal of cell biology. JCB. Bd. 135. H. 1. New York, NY: Rockefeller Univ. Press 1996 S. 227 - 240

Labosky, Patricia A.; Winnier, Glenn E.; Sasaki, Hiroshi et al.
Short Communication: The Chromosomal Mapping of Four Genes Encoding Winged Helix Proteins Expressed Early in Mouse Development
Genomics. internat. journal of gene mapping and nucleotide sequencing ; emphasizing analyses of the human and other complex genomes. Bd. 34. H. 2. San Diego, Calif. [u.a.]: Elsevier 1996 S. 241 - 245

Winnier, Glenn; Blessing, Manfred; Labosky, Patricia A. et al.
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
Genes & development. a journal of celluar and molecular biology. Bd. 9. H. 17. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press 1995 S. 2105 - 2116

Blessing, Manfred; Nanney, Lillian B.; King, Lloyd E. et al.
Chemical Skin Carcinogenesis is Prevented in Mice by the Induced Expression of a TGF-b Related Transgene
Teratogenesis, carcinogenesis, and mutagenesis. Bd. 15. H. 1. New York, NY: Liss 1995 S. 11 - 22

Megosh, Louis; Gilmour, Susan K.; Rosson, Dan et al.
Increased Frequency of Spontaneous Skin Tumors in Transgenic Mice Which Overexpress Ornithine Decarboxylase
Cancer research. an official organ of the American Association for Cancer Research. Bd. 55. H. 19. Birmingham, Ala. [u.a.]: AACR 1995 S. 4205 - 4209

Casatorres, José; Navarro, J.Manuel; Blessing, Manfred et al.
Analysis of the control of expression and tissue specificity of the keratin 5 gene, characteristic of basal keratinocytes. Fundamental role of an AP-1 element
The journal of biological chemistry. JBC. Bd. 269. H. 32. Bethesda, Md.: ASBMB 1994 S. 20489 - 20496

Hogan, B.L.M.; Blessing, Manfred; Winnier, G.E. et al.
Growth factors in development: The role of TGF-b related polypeptide signalling molecules in embryogenesis
Development. H. Supplement. Cambridge: The Company of Biologists 1994 S. 53 - 60

Wall, N.A.; Blessing, M.; Wright, C.V.E. et al.
Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6).
The journal of cell biology. JCB. Bd. 120. H. 2. New York, NY: Rockefeller Univ. Press 1993 S. 493 - 502

Blessing, M.; Rüther, U.; Franke, W.W.
Ectopic synthesis of epidermal cytokeratins in pancreatic islet cells of transgenic mice interferes with cytoskeletal order and insulin production.
The journal of cell biology. JCB. Bd. 120. H. 3. New York, NY: Rockefeller Univ. Press 1993 S. 743 - 756

Werner, S.; Weinberg, W.; Liao, X. et al.
Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation
The EMBO journal. Bd. 12. H. 7. London: Nature Publ. Group 1993 S. 2635 - 2644

Blessing, Manfred; Nanney, Lillian B.; King, Lloyd E. et al.
Transgenic mice as a model to study the role of TGF-b-related molecules in hair follicles
Genes & development. a journal of celluar and molecular biology. Bd. 7. H. 2. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press 1993 S. 204 - 215

Fries, R.; Threadgill, D. W.; Hediger, R. et al.
Mapping of bovine cytokeratin sequences to four different sites on three chromosomes
Cytogenet Cell Genet. Bd. Cytogenet Cell Genet. 1991 S. 135-41

Bailleul, B.; Surani, M. A.; White, S. et al.
Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter
Cell. Bd. Cell. 1990 S. 697-708

Blessing, M.; Jorcano, J. L.; Franke, W. W.
Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes
EMBO Journal. Bd. EMBO Journal. 1989 S. 117-26

Blessing, M.; Zentgraf, H.; Jorcano, J. L.
Differentially expressed bovine cytokeratin genes. Analysis of gene linkage and evolutionary conservation of 5´-upstream sequences
EMBO Journal. Bd. EMBO Journal. 1987 S. 567-75

Lehnert, M. E.; Jorcano, J. L.; Zentgraf, H. et al.
Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins
EMBO Journal. Bd. EMBO Journal. 1984 S. 3279-87