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Publikationen
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Platt, KL; Aderhold, S; Kulpe, K et al.

Unexpected DNA damage caused by polycyclic aromatic hydrocarbons under standard laboratory conditions

Mutat Res. Bd. 650. H. 2. 2008 S. 96-103


Christmann, M; Tomicic, MT; Gestrich, C et al.

WRN protects against topo I but not topo II inhibitors by preventing DNA break formation

DNA Repair (Amst). Bd. 7. H. 12. 2008 S. 1999-2009


Christmann, M; Tomicic-Christmann, MT; Origer, J et al.

A role for c-Fos in the regulation of DNA repair and protection against ultraviolet light-induced cell death

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 84


Christmann, M; Tomicic, MT; Aasland, D et al.

A role for UV-light-induced c-Fos: Stimulation of nucleotide excision repair and protection against sustained JNK activation and apoptosis.

Carcinogenesis. Bd. 28. H. 1. 2007 S. 183-90


Roos, WP; Batista, LFZ; Naumann, S et al.

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

Oncogene. Bd. 26. 2007 S. 186-197


Briegert, M; Enk, AH; Kaina, B

Change in expression of MGMt during maturation of human monocytes into dendritic cells

DNA Repair. Bd. 6. 2007 S. 1255-1263


Efferth, T; Kaina, B

Chemical Carcinogenesis: Genotoxic and Non-genotoxic Mechanisms

H. Greim and R. Snyder (Hrsg). Toxicology and Risk Assessment: A Comprehensive Introduction. John Wiley & Sons Ltd. 2007


Rebillard, A; Tekpli, X; Meurette, O et al.

Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells

Cancer Res. Bd. 67. 2007 S. 7865-7874


Nagel, G; Wiewrodt, D; Perneczky, A et al.

Comparing MGMT activity and promoter methylation in glioblastomas as predictive tools

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 85


Carmo, H; Brulport, M; Hermes, M et al.

CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA)

Toxicology. Bd. 229. 2007 S. 236-244



Steiner, E; Plata, K; Interthal, C et al.

Diabetes mellitus is a multivariate independent prognostic factor in endometrial carcinoma: a clinicopathologic study on 313 patients.

Eur J Gynaecol Oncol. Bd. 28. H. 2. 2007 S. 95-7



Christmann, M; Roos, WP; Kaina, B

DNA methylation damage: Formation, repair and biological consequences

Obe and Vijayalaxmi (Hrsg). Chromosomal alterations: Methods, results and importance in human health. Berlin-Heidelberg-New York: Springer-Verlag 2007


Oesch, F; Fabian, E; Oesch-Bartlomowicz, B et al.

Drug metabolizing enzymes in the skin of man, rat and pig

Drug Metab Rev. Bd. 39. 2007 S. 659-698



Efferth, T; Li, PCH; Badireenath Konkimalla, VS et al.

From traditional Chinese medicine to rational cancer therapy

Trends in Molecular Medicine. Bd. 13. H. 8. 2007 S. 353-361


Bockamp, Ernesto; Christel, Cerstin; Hameyer, Dorothe et al.

Generation and characterization of tTS-H4: a novel transcriptional repressor that is compatibte with the reverse tetracycline-controtted TET-ON system

JOURNAL OF GENE MEDICINE. Bd. 9. H. 4. 2007 S. 308-318


Holthöfer, B; Eshkind, L; Windoffer, R et al.

Generation of conditional tissue-specific desmoglein 2 null mutant mice

Eur J Cell Biol. Bd. 86S1. H. 57. 2007 S. 37


Fritz, G; Brachetti, T; Kaina, B

Genotoxin-induced DNA replication blockage is involved in the regulation of stress kinases (SAPK/JNK)

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 91



Faust, D; Schreck, I; Oesch, F et al.

Identification of the JunD-Interaction partner in AhR-dependent regulation of cyclin A expression

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 88


Jöst, E; Roos, WP; Schmidberger, H et al.

IFN induced cell kill in pancreatic cancer cell lines on its own and sensitizes these cells in combination with ionising radiation

Naunyn Schmiedebergs Arch Pharmacol. Bd. 417. 2007 S. 84


Christmann, M; Fritz, G; Kaina, B

Induction of DNA repair genes in mammalian cells in response to genotoxic stress

Lankenau, D. (Hrsg). Genome Integrity: Facets and Perspectives. Berlin-Heidelberg: Springer Verlag 2007


Damrot, J; Kaina, B; Fritz, G

Involvement of DNA repair factors in late activation of stress kinases (SAPK/JNK) by DNA cross-linking agents

Naunyn Schmiedebergs Arch Pharmacol. Bd. 372. 2007 S. 120-120


Gestrich, C; Christmann, M; Kaina, B

Involvement of WRN helicase in the resistance to topoisomerase I and II inhibitors

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 85



Köberle, B; Dürk, H; Schmitt, S et al.

Low levels of XPA protein do not account for the sensitivity of testis tumor cells to cisplatin and UV irradiation

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 84


Goldstein, M; Roos, WP; Kaina, B

Mafosfamide induced apoptosis in human lymphoblastoid cells: Role of DNA replication, RNA transcription, p53 and Chk1/Chk2

Naunyn Schmiedebergs Arch Pharmacol. Bd. 402. 2007 S. 82


Hengstler, J. G.; Brulport, M.; Hermes, M. et al.

Mathematical modelling of liver regeneration after intoxication with CCI4

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 375. 2007 S. 77-77


Roos, WP; Batista, LFZ; Naumann, SC et al.

Mechanism of methylating agent induced cell death: Roles of MGMT, mismatch repair and DNA double-strand break repair

Naunyn Schmiedebergs Arch Pharmacol. Bd. 404. 2007 S. 82


Oesch-Bartlomowicz, B; Oesch, F

Mechanisms of toxication and detoxication which challenge drug candidates and drugs

D. Triggle and J. Taylor (Hrsg). Comprehensive Medical Medicine. Philadelphia: Elsevier 2007


Kaina, B; Christmann, M; Naumann, S et al.

MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

DNA Repair. Bd. 6. 2007 S. 1079-1099


Rauh, Rolf; Kahl, Stefan; Boechzelt, Herbert et al.

Molecular biology of cantharidin in cancer cells

Chinese medicine. Bd. 2. London: BioMed Central 2007 8




Schulz, F; Huelsenbeck, J; Gerhard, R et al.

P38 MAP kinase and the cytotoxic effect of clostridium difficile toxin B

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 38


Cabezas-Wallscheid, N.; Eshkind, L.; Antunes, C. et al.

Protection of haematopoietic stem cells (HSC) against high-dose chemotherapy by virtue of the O'-methylguanine-DNA-methyltransferase (MGMT) repair enzyme

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 375. 2007 S. 85-85


Naumann, SC; Roos, WP; Christmann, M et al.

Role of E2F-1/p73 apoptosis signalling in fotemustine treated malignant melanoma cells

Naunyn Schmiedebergs Arch Pharmacol. Bd. 401. 2007 S. 82


Weiss, C; Faust, D; Schreck, I et al.

TCDD deregulates contact-inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A

Oncogene. 2007 S. 1-10




Tomicic-Christmann, M; Christmann, M; Kaina, B

Topotecan-driven degradation of topoisomerase I is p53-dependent affecting cell survival: Role of gamma-H2AX-phosphorylation, caspase activation and survival

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 85


Hameyer, Dorothe; Loonstra, Ate; Eshkind, Leonid et al.

Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues

PHYSIOLOGICAL GENOMICS. Bd. 31. H. 1. 2007 S. 32-41


Meyer, HJ; Dreger, S; Fritz, G et al.

Up-regulation of RhoB by the cytotoxic necrotizing factor 1 from Escherichia coli

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. 2007 S. 38



Batista, LFZ; Roos, WP; Kaina, B et al.

UV-induced lesions trigger apoptosis in p53-mutated glioma cells

Naunyn Schmiedebergs Arch Pharmacol. Bd. 403. 2007 S. 82


Schulte-Hermann, R; Wogan, GN; Berry, C et al.

Analysis of reproductive toxicity and classification of glufosinate ammonium

Regul Toxicol Pharmacol. Bd. 44. 2006 S. 1-76


Kaina, B; Roos, W

Apoptosis induced by DNA-damaging agents

K. M. Debatin and S. Fulda (Hrsg). Apoptosis and Cancer Therapy - Frim Cutting-edge Science to Novel Therapeutic Concepts. Weinheim: Wiley-VHC 2006