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Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expressionCELL DEATH & DISEASE. Bd. 13. H. 4. 2022
Beyer, Mandy; Henninger, Sven J.; Haehnel, Patricia S. et al.
Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cellsCELL CHEMICAL BIOLOGY. Bd. 29. H. 3. 2022 S. 398-+
Kiweler, Nicole; Schwarz, Helena; Nguyen, Alexandra et al.
The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracilCELL BIOLOGY AND TOXICOLOGY. 2022
Franzese, Ornella; Torino, Francesco; Giannetti, Elisa et al.
Abscopal Effect and Drug-Induced Xenogenization: A Strategic Alliance in Cancer Treatment?INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 22. H. 19. 2021
Beltzig, Lea; Stratenwerth, Bjoern; Kaina, Bernd
Accumulation of Temozolomide-Induced Apoptosis, Senescence and DNA Damage by Metronomic Dose Schedule: A Proof-of-Principle Study with Glioblastoma CellsCANCERS. Bd. 13. H. 24. 2021
Seiwert, Nina; Adam, Janine; Steinberg, Pablo et al.
Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivoARCHIVES OF TOXICOLOGY. Bd. 95. H. 7. 2021 S. 2507-2522
Nguyen, Alexandra; Dzulko, Melanie; Murr, Janine et al.
Class 1 Histone Deacetylases and Ataxia-Telangiectasia Mutated Kinase Control the Survival of Murine Pancreatic Cancer Cells upon dNTP DepletionCELLS. Bd. 10. H. 10. 2021
Heylmann, Daniel; Ponath, Viviane; Kindler, Thomas et al.
Comparison of DNA repair and radiosensitivity of different blood cell populationsSCIENTIFIC REPORTS. Bd. 11. H. 1. 2021
Seiwert, Nina; Fahrer, Joerg; Nagel, Georg et al.
Curcumin Administered as Micellar Solution Suppresses Intestinal Inflammation and Colorectal CarcinogenesisNUTRITION AND CANCER-AN INTERNATIONAL JOURNAL. Bd. 73. H. 4. 2021 S. 686-693
Beltzig, Lea; Frumkina, Anna; Schwarzenbach, Christian et al.
Cytotoxic, Genotoxic and Senolytic Potential of Native and Micellar CurcuminNUTRIENTS. Bd. 13. H. 7. 2021
Liebl, Magdalena C.; Moehlenbrink, Jutta; Becker, Huong et al.
DAZAP2 acts as specifier of the p53 response to DNA damageNUCLEIC ACIDS RESEARCH. Bd. 49. H. 5. 2021 S. 2759-2776
Toutah, Krimo; Nawar, Nabanita; Timonen, Sanna et al.
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic LeukemiaJOURNAL OF MEDICINAL CHEMISTRY. Bd. 64. H. 12. 2021 S. 8486-8509
Mueller, Nadine; Ponkkonen, Eveliina; Carell, Thomas et al.
Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis-Element in Response to 5-Formylcytosine and 5-CarboxycytosineINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 22. H. 20. 2021
Tomicic, Maja T.; Dawood, Mona; Efferth, Thomas
Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal CarcinomaCANCERS. Bd. 13. H. 16. 2021
Dietrich, Cornelia; Hofmann, Thomas G.
Ferroptosis Meets Cell-Cell ContactsCELLS. Bd. 10. H. 9. 2021
Kadioglu, Onat; Saeed, Mohamed E. M.; Greten, Henry J. et al.
Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cellsJOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. Bd. 84. H. 4. 2021 S. 1086-1089
Beltzig, L.; Stratenwerth, B.; Christmann, M. et al.
Identification of senolytic agents for sequential treatment of glioblastoma with temozolomideNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 394. H. SUPPL 1. 2021 S. S30-S30
Berte, Nancy; Eich, Marcus; Heylmann, Daniel et al.
Impaired DNA repair in mouse monocytes compared to macrophages and precursorsDNA REPAIR. Bd. 98. 2021
Hassan, Zonera; Schneeweis, Christian; Wirth, Matthias et al.
Important role of Nfkb2 in the Kras(G12D)-driven carcinogenesis in the pancreasPANCREATOLOGY. Bd. 21. H. 5. 2021 S. 912-919
Wachholz, Vanessa; Mustafa, Al-Hassan M.; Zeyn, Yanira et al.
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3ARCHIVES OF TOXICOLOGY. Bd. 96. H. 1. 2021 S. 177-193
Reich, Thomas R.; Schwarzenbach, Christian; Vilar, Juliana Brandstetter et al.
Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombinationCELLULAR AND MOLECULAR LIFE SCIENCES. Bd. 78. H. 14. 2021 S. 5587-5604
Marx, Christian; Sonnemann, Juergen; Beyer, Mandy et al.
Mechanistic insights into p53-regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cellsMOLECULAR ONCOLOGY. Bd. 15. H. 12. 2021 S. 3404-3429
Haas, Bodo; Ciftcioglu, Janine; Jermar, Sanja et al.
Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependentJOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. Bd. 147. H. 3. 2021 S. 779-792
Stratenwerth, Bjoern; Geisen, Susanne M.; He, Yang et al.
Molecular Dosimetry of Temozolomide: Quantification of Critical Lesions, Correlation to Cell Death Responses, and Threshold DosesMOLECULAR CANCER THERAPEUTICS. Bd. 20. H. 10. 2021 S. 1789-1799
Jiso, Apisada; Demuth, Philipp; Bachowsky, Madeleine et al.
Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal CancerCANCERS. Bd. 13. H. 13. 2021
Mustafa, Al-Hassan M.; Kraemer, Oliver H.
Novel insight into mechanisms for ATR activation by chromatin structuresARCHIVES OF TOXICOLOGY. Bd. 95. H. 10. 2021 S. 3433-3434
Kaina, Bernd
On the Origin of SARS-CoV-2: Did Cell Culture Experiments Lead to Increased Virulence of the Progenitor Virus for Humans?IN VIVO. Bd. 35. H. 3. 2021 S. 1313-1326
Pons, Miriam; Zeyn, Yanira; Zahn, Stella et al.
Oncogenic Kinase Cascades Induce Molecular Mechanisms That Protect Leukemic Cell Models from Lethal Effects of De Novo dNTP Synthesis InhibitionCANCERS. Bd. 13. H. 14. 2021
Tomicic, Maja T.; Kraemer, Franziska; Nguyen, Alexandra et al.
Oxaliplatin-Induced Senescence in Colorectal Cancer Cells Depends on p14(ARF)-Mediated Sustained p53 ActivationCANCERS. Bd. 13. H. 9. 2021
Mueller, Nadine; Khobta, Andriy
Regulation of GC box activity by 8-oxoguanineREDOX BIOLOGY. Bd. 43. 2021
Seiwert, N.; Kostka, T.; Empl, M. et al.
Repair of O-6-carboxymethylguanine adducts by MGMT in human colonic epithelial cellsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 394. H. SUPPL 1. 2021 S. S12-S12
Kostka, Tina; Empl, Michael T.; Seiwert, Nina et al.
Repair of O-6-carboxymethylguanine adducts by O-6-methylguanine-DNA methyltransferase in human colon epithelial cellsCARCINOGENESIS. Bd. 42. H. 8. 2021 S. 1110-1118
Arnold, Frank; Gout, Johann; Wiese, Heike et al.
RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic CancerCANCER RESEARCH. Bd. 81. H. 7. 2021 S. 1758-1774
Goeder, Anja; Ginter, Torsten; Heinzel, Thorsten et al.
STAT1 N-terminal domain discriminatively controls type I and type II IFN signalingCYTOKINE. Bd. 144. 2021
Schmalohr, Benjamin Franz; Mustafa, Al-Hassan M.; Kraemer, Oliver H. et al.
Structural Insights into the Interaction of Heme with Protein Tyrosine Kinase JAK2**CHEMBIOCHEM. Bd. 22. H. 5. 2021 S. 861-864
Neitzel, C.; Demuth, P.; Seiwert, N. et al.
Synergism of the metabolic inhibitor CPI-613 and genotoxic chemotherapeutics in colorectal cancer therapy through a p53-independent mitochondrial apoptosis pathwayNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 394. H. SUPPL 1. 2021 S. S7-S8
Gout, Johann; Perkhofer, Lukas; Morawe, Mareen et al.
Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancerGUT. Bd. 70. H. 4. 2021 S. 743-760
Schwarzenbach, Christian; Tatsch, Larissa; Vilar, Juliana Brandstetter et al.
Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide TreatmentCANCERS. Bd. 13. H. 14. 2021
Schwarzenbach, C.; Tatsch, L.; Kaina, B. et al.
Targeting the SCAP factors c-IAP1, c-IAP2 and Bcl-2 eliminates senescent cells and enhances TMZ-induced cell killing of glioblastoma cellsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 394. H. SUPPL 1. 2021 S. S30-S30
Walter, Karolin; Rodriguez-Aznar, Eva; Ferreira, Monica S. Ventura et al.
Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem CellsCANCERS. Bd. 13. H. 13. 2021
Formes, Henning; Bernardes, Joana P.; Mann, Amrit et al.
The gut microbiota instructs the hepatic endothelial cell transcriptomeISCIENCE. Bd. 24. H. 10. 2021
Liebl, Magdalena C.; Hofmann, Thomas G.
The Role of p53 Signaling in Colorectal CancerCANCERS. Bd. 13. H. 9. 2021
Kaina, Bernd
A genome-wide screening for DNA repair genes: much more players than hitherto knownSIGNAL TRANSDUCTION AND TARGETED THERAPY. Bd. 5. H. 1. 2020
Sellmer, Andreas; Pilsl, Bernadette; Beyer, Mandy et al.
A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemiaEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. Bd. 193. 2020
Ziegler, Verena; Deussen, Marco; Schumacher, Lena et al.
Anticancer drug and ionizing radiation-induced DNA damage differently influences transcription activity and DDR-related stress responses of an endothelial monolayerBIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. Bd. 1867. H. 6. 2020
Matos-Rodrigues, Gabriel E.; Grigaravicius, Paulius; Lopez, Bernard S. et al.
ATRIP protects progenitor cells against DNA damage in vivoCELL DEATH & DISEASE. Bd. 11. H. 10. 2020
Matos-Rodrigues, Gabriel E.; Grigaravicius, Paulius; Lopez, Bernard S. et al.
ATRIP protects progenitor cells against DNA damage in vivo (vol 11, 923, 2020)CELL DEATH & DISEASE. Bd. 11. H. 12. 2020
Allmann, Sebastian; Mayer, Laura; Olma, Jessika et al.
Benzo[a]pyrene represses DNA repair through altered E2F1/E2F4 function marking an early event in DNA damage-induced cellular senescenceNUCLEIC ACIDS RESEARCH. Bd. 48. H. 21. 2020 S. 12085-12101
Kaina, Bernd; Beltzig, Lea; Piee-Staffa, Andrea et al.
Cytotoxic and Senolytic Effects of Methadone in Combination with Temozolomide in Glioblastoma CellsINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 21. H. 19. 2020
Rodriguez-Alvarez, M.; Sarmini, L.; Kim, D. et al.
Direct detection f mutatins arising at a damage sith in DNANAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 393. H. SUPPL 1. 2020 S. 4-4
Rodriguez-Alvarez, Marta; Kim, Daria; Khobta, Andriy
EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA LesionsBIOMOLECULES. Bd. 10. H. 6. 2020
Taubmann, Andreas; Willershausen, Ines; Walter, Christian et al.
Genotoxic and cytotoxic potential of methacrylate-based orthodontic adhesivesCLINICAL ORAL INVESTIGATIONS. 2020
Seiwert, Nina; Wecklein, Sabine; Demuth, Philipp et al.
Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic ironCELL DEATH & DISEASE. Bd. 11. H. 9. 2020
Kiweler, Nicole; Wuensch, Desiree; Wirth, Matthias et al.
Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processesJOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. Bd. 146. H. 2. 2020 S. 343-356
Friedrich, Annabelle; Assmann, Ann-Sophie; Schumacher, Lena et al.
In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi)INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 21. H. 13. 2020
Seiwert, Nina; Heylmann, Daniel; Hasselwander, Solveig et al.
Mechanism of colorectal carcinogenesis triggered by heme iron from red meatBIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. Bd. 1873. H. 1. 2020
Frappart, Pierre-Olivier; Hofmann, Thomas G.
Pancreatic Ductal Adenocarcinoma (PDAC) Organoids: The Shining Light at the End of the Tunnel for Drug Response Prediction and Personalized MedicineCANCERS. Bd. 12. H. 10. 2020
Bergholz, Liana M.; Grimminger, Peter; Dikeoulia, Elsa et al.
Pilot Study on Malnutrition and DNA Damage in Patients with Newly Diagnosed Gastrointestinal Tumors: Is DNA Damage Reversible by Early Individualized Nutritional Support?JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES. Bd. 29. H. 4. 2020 S. 569-577
Matos-Rodrigues, Gabriel E.; Tan, Pedro B.; Rocha-Martins, Mauricio et al.
Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndromeDISEASE MODELS & MECHANISMS. Bd. 13. H. 10. 2020
Gomes, Anielle L.; Matos-Rodrigues, Gabriel E.; Frappart, Pierre-Olivier et al.
RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated ApoptosisFRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. Bd. 8. 2020
Lankes, Katharina; Hassan, Zonera; Doffo, Maria Josefina et al.
Targeting the ubiquitin-proteasome system in a pancreatic cancer subtype with hyperactive MYCMOLECULAR ONCOLOGY. Bd. 14. H. 12. 2020 S. 3048-3064
Dzulko, Melanie; Pons, Miriam; Henke, Andreas et al.
The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformationBIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. Bd. 1874. H. 2. 2020
Volcic, Meta; Sparrer, Konstantin M. J.; Koepke, Lennart et al.
Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1NATURE MICROBIOLOGY. Bd. 5. H. 10. 2020 S. 1247-+
He, Yang; Kaina, Bernd
Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide?INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 20. H. 7. 2019
Liebl, Magdalena C.; Hofmann, Thomas G.
Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death RoadBIOESSAYS. Bd. 41. H. 12. 2019
Wenz, Christine; Faust, Dagmar; Linz, Berenike et al.
Cell-cell contacts protect against t-BuOOH-induced cellular damage and ferroptosis in vitroARCHIVES OF TOXICOLOGY. Bd. 93. H. 5. 2019 S. 1265-1279
Ponath, Viviane; Heylmann, Daniel; Haak, Tobias et al.
Compromised DNA Repair and Signalling in Human GranulocytesJOURNAL OF INNATE IMMUNITY. Bd. 11. H. 1. 2019 S. 74-85
Mahn, Friederike L.; Castven, Darko; Pereira, Sharon P. et al.
DECIPHERING THE ROLE OF PARP-1 AS A THERAPEUTIC TARGET IN KRAS-MUTATED INTRAHEPATIC CHOLANGIOCARCINOMAHEPATOLOGY. Bd. 70. 2019 S. 1143A-1143A
Kaina, Bernd; Christmann, Markus
DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureasDNA REPAIR. Bd. 78. 2019 S. 128-141
Kaina, Bernd; Christmann, Markus
DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas (vol 78, pg 128, 2019)DNA REPAIR. Bd. 80. 2019 S. 93-93
Heinz, Kathrin S.; Rapp, Alexander; Casas-Delucchi, Corella S. et al.
DNA replication dynamics of vole genome and its epigenetic regulationEPIGENETICS & CHROMATIN. Bd. 12. 2019
Gogiraju, Rajinikanth; Hubert, Astrid; Fahrer, Joerg et al.
Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR SignalingCIRCULATION-HEART FAILURE. Bd. 12. H. 1. 2019
Christmann, Markus; Kaina, Bernd
Epigenetic regulation of DNA repair genes and implications for tumor therapyMUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. Bd. 780. 2019 S. 15-28
Rund, Katharina M.; Heylmann, Daniel; Seiwert, Nina et al.
Formation of trans-epoxy fatty acids correlates with formation of isoprostanes and could serve as biomarker of oxidative stressPROSTAGLANDINS & OTHER LIPID MEDIATORS. Bd. 144. 2019
Tomicic, Maja T.; Steigerwald, Christian; Rasenberger, Birgit et al.
Functional mismatch repair and inactive p53 drive sensitization of colorectal cancer cells to irinotecan via the IAP antagonist BV6ARCHIVES OF TOXICOLOGY. Bd. 93. H. 8. 2019 S. 2265-2277
Beyer, Mandy; Romanski, Annette; Mustafa, Al-Hassan M. et al.
HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of beta-catenin, MYC, and WT1CANCERS. Bd. 11. H. 10. 2019
Pons, Miriam; Nagel, Georg; Zeyn, Yanira et al.
Human Platelet Lysate as Validated Replacement for Animal Serum to Assess ChemosensitivityALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION. Bd. 36. H. 2. 2019 S. 277-288
Kress, Joana M.; Di Dio, Lorella; Heck, Larissa et al.
Human primary endothelial cells are impaired in nucleotide excision repair and sensitive to benzo[a]pyrene compared with smooth muscle cells and pericytesSCIENTIFIC REPORTS. Bd. 9. 2019
Liebl, M. C.; Hofmann, T. G.
Identification of responders to immune checkpoint therapy: which biomarkers have the highest value?JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. Bd. 33. 2019 S. 52-56
Kraus, Alexander; McKeague, Maureen; Seiwert, Nina et al.
Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O-6-methylguanine in vivoARCHIVES OF TOXICOLOGY. Bd. 93. H. 2. 2019 S. 559-572
Neitzel, Carina; Seiwert, Nina; Goeder, Anja et al.
Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal DegradationCELLS. Bd. 8. H. 8. 2019
Kitsera, Nataliya; Rodriguez-Alvarez, Marta; Emmert, Steffen et al.
Nucleotide excision repair of abasic DNA lesionsNUCLEIC ACIDS RESEARCH. Bd. 47. H. 16. 2019 S. 8537-8547
Guo, Haihong; Treude, Fabian; Kraemer, Oliver H. et al.
PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1SCIENTIFIC REPORTS. Bd. 9. 2019
Tomicic, M.; Steigerwald, C.; Rasenberger, B. et al.
Survivin inhibitor LLP3 sensitizes colorectal cancer cells to irinotecan in the context of a specific XAF1/p53 signatureNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 392. 2019 S. S9-S9
Aasland, Dorthe; Goetzinger, Laura; Hauck, Laura et al.
Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR-CHK1, p21, and NF-kappa BCANCER RESEARCH. Bd. 79. H. 1. 2019 S. 99-113
He, Yang; Roos, Wynand P.; Wu, Qianchao et al.
The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell DeathMOLECULAR CANCER RESEARCH. Bd. 17. H. 5. 2019 S. 1129-1141
Laarmann, Kathrin; Kress, Joana M.; Kaina, Bernd et al.
Werner syndrome (WRN) DNA helicase and base excision repair (BER) factors maintain endothelial homeostasisDNA REPAIR. Bd. 73. 2019 S. 17-27
Zaini, Mohamad A.; Mueller, Christine; de Jong, Tristan V. et al.
A p300 and SIRT1 Regulated Acetylation Switch of C/EBP alpha Controls Mitochondrial FunctionCELL REPORTS. Bd. 22. H. 2. 2018 S. 497-511
Neitzel, C.; Stroh, S.; Nagel, G. et al.
A promising building block in the chemotherapy of colorectal cancer: The first-in-class mitochondrial disruptor CPI-613NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 391. 2018 S. S58-S58
Seiwert, N.; Neitzel, C.; Stroh, S. et al.
AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cellsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 391. 2018 S. S51-S51
Korfei, Martina; Stelmaszek, Daniel; MacKenzie, BreAnne et al.
Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosisPLOS ONE. Bd. 13. H. 11. 2018
Leonhardt, Michel; Sellmer, Andreas; Kraemer, Oliver H. et al.
Design and biological evaluation of tetrahydro-beta-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitorsEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. Bd. 152. 2018 S. 329-357
Rund, Katharina M.; Ostermann, Annika I.; Kutzner, Laura et al.
Development of an LC-ESI(-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3-and n6-PUFAsANALYTICA CHIMICA ACTA. Bd. 1037. 2018 S. 63-74
Stojanovic, Nikolina; Dekanic, Ana; Paradzik, Mladen et al.
Differential Effects of Integrin alpha v Knockdown and Cilengitide on Sensitization of Triple-Negative Breast Cancer and Melanoma Cells to Microtubule PoisonsMOLECULAR PHARMACOLOGY. Bd. 94. H. 6. 2018 S. 1334-1351
Herrtwich, Laura; Nanda, Indrajit; Evangelou, Konstantinos et al.
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas (vol 167, pg 1264, 2016)CELL. Bd. 174. H. 5. 2018 S. 1325-1326
Gock, Michael; Mullins, Christina S.; Harnack, Christine et al.
Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell lineWORLD JOURNAL OF GASTROENTEROLOGY. Bd. 24. H. 33. 2018 S. 3749-3759
Gock, Michael; Mullins, Christina S.; Bergner, Carina et al.
Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell linesWORLD JOURNAL OF GASTROENTEROLOGY. Bd. 24. H. 43. 2018 S. 4880-4892
Goeder, Anja; Emmerich, Claudia; Nikolova, Teodora et al.
HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130NATURE COMMUNICATIONS. Bd. 9. 2018
Beyer, M; Kiweler, N; Mahboobi, S et al.
How to Distinguish Between the Activity of HDAC1-3 and HDAC6 with Western BlotOliver H. Krämer (Hrsg). HDAC/HAT Function Assessment and Inhibitor Development: Methods and protocols, Methods in Molecular Biology. Springer Science + Business Media, New York 2018