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Intrinsic Anticancer Drug Resistance of Malignant Melanoma Cells Is Abrogated by IFN-beta and Valproic AcidCANCER RESEARCH. Bd. 71. H. 12. 2011 S. 4150-4160
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Investigation of base excision repair in proliferating and arrested cultures of fibroblastsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 97-97
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Knockdown of Fra-1 sensitizes human glioblastoma cells to the anticancer drug nimustine (ACNU)NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 101-102
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Lack of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is accompanied by increased CK2 alpha' levelsMOLECULAR AND CELLULAR BIOCHEMISTRY. Bd. 356. H. 1-2. 2011 S. 139-147
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Late Activation of Stress-activated Protein Kinases/c-Jun N-terminal Kinases Triggered by Cisplatin-induced DNA Damage in Repair-defective CellsJOURNAL OF BIOLOGICAL CHEMISTRY. Bd. 286. H. 15. 2011 S. 12991-13001
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Lovastatin protects cardiomyoblasts from doxorubicin-induced cytotoxicity by antagonizing topoisomerase II cleavable complex formationNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 49-49
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Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cellsCANCER LETTERS. Bd. 304. H. 1. 2011 S. 60-69
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O-6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistryBIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. Bd. 1816. H. 2. 2011 S. 179-190
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O(6)-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smokeMutation Research. 2011 S. 1-11
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Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agentsBRITISH MEDICAL BULLETIN. Bd. 97. H. 1. 2011 S. 17-26
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Rac1-Regulated Endothelial Radiation Response Stimulates Extravasation and Metastasis That Can Be Blocked by HMG-CoA Reductase InhibitorsPLOS ONE. Bd. 6. H. 10. 2011 S. -
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Rad51 and BRCA2-New Molecular Targets for Sensitizing Glioma Cells to Alkylating Anticancer DrugsPLOS ONE. Bd. 6. H. 11. 2011 S. -
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Regulation of ERK-1/2 activity upon contact inhibition in fibroblastsBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. Bd. 406. H. 3. 2011 S. 483-487
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Survivin inhibition and DNA double-strand break repair: A molecular mechanism to overcome radioresistance in glioblastomaRADIOTHERAPY AND ONCOLOGY. Bd. 101. H. 1. 2011 S. 51-58
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Synthesis and biological evaluation of 4-nitro-substituted 1,3-diaryltriazenes as a novel class of potent antitumor agentsFEBS JOURNAL. Bd. 278. 2011 S. 333-333
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Synthesis, Absolute Configuration, and Bacterial Mutagenicity of the 8 Stereoisomeric Vicinal Diol Epoxides at the Terminal Benzo Ring of Carcinogenic Dibenz[a,h]anthraceneCHEMICAL RESEARCH IN TOXICOLOGY. Bd. 24. H. 12. 2011 S. 2258-2268
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Targeting of cancer cells with a glucose-conjugated DNA-repair-inhibitorNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 101-101
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The AHR in the Control of Cell Cycle and ApoptosisR. Pohjanvirta (edt.) The Ah Receptor in Biology and Toxicology. John Wiley & Sons, Inc. 2011
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The influence of the TCM drug artesunate on the sensitivity of tumor cell lines and his cytotoxic an genotoxic activityNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 101-101
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Topotecan-induced cell death of malignant glloma cells is abrogated by p53NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 8-9
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Toxicities by Herbal Medicines with Emphasis to Traditional Chinese MedicineCURRENT DRUG METABOLISM. Bd. 12. H. 10. 2011 S. 989-996
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Wnt-factors affect the functional state of dendritic cellsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 34-34
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A novel conditional mouse model for studying intestinal cancerNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 84-84
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A novel role for c-Fos/AP-1 in the regulation of XPF endonuclease in UV-irradiated human fibroblastsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 72-72
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A Quest for Initiating Cells of Head and Neck Cancer and their TreatmentCancers. Bd. 2. 2010 S. 1528-1554
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A role for resveratrol and curcumine in sensitization of glioblastoma cells to alkylating chemotherapeuticsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 72-72
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ATM deficiency leads to hypersensitivity and cell death execution via necrosis following genotoxic insultNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 71-71
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Beneficial effects of the HMG-CoA reductase inhibitor lovastatin on ionizing radiation- and doxorubicin-induced cytotoxicity in vivoNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 42-42
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Both base excision repair and O-6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesisCARCINOGENESIS. Bd. 31. H. 12. 2010 S. 2111-2117
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Cell death by apoptosis executed several cell cycles after DNA damage inductionNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 70-70
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Cisplatin resistance: Preclinical findings and clinical implicationsBIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. Bd. 1806. H. 2. 2010 S. 172-182
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DNA damage response and the balance between cell survival and cell deathThe Humana Press (Hrsg). Z. Siddik (edt.) Checkpoint Response in Cancer Therapy. Springer Science 2010
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DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instabilityPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 107. H. 30. 2010 S. 13390-13395
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Downregulation of RhoB GTPase confers resistance to cisplatin in human laryngeal carcinoma cellsCANCER LETTERS. Bd. 295. H. 2. 2010 S. 182-190
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ERCC1 and XPF expression in human testicular germ cell tumorsONCOLOGY REPORTS. Bd. 23. H. 1. 2010 S. 223-227
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Exogenously inducible and reversible activation of canonical Wnt-signalling in the lungNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 84-84
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Fruits and vegetables protect against the genotoxicity of heterocyclic aromatic amines activated by human xenobiotic-metabolizing enzymes expressed in immortal mammalian cellsMUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS. Bd. 703. H. 2. 2010 S. 90-98
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Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonateDNA REPAIR. Bd. 9. H. 10. 2010 S. 1050-1063
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Induction of base excision repair proteins by IL-4 and GM-CSF during monocytic maturationNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 72-72
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Key role of homologous recombination in the protection of cells following treatment with methylating genotoxinsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 73-73
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Metastases of squamous cell carcinoma of the head and neck show increased levels of nucleotide excision repair protein XPF in vivo that correlate with increased chemoresistance ex vivoINTERNATIONAL JOURNAL OF ONCOLOGY. Bd. 36. H. 5. 2010 S. 1277-1284
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MGMT Activity in Mucosal Epithelium and Squamous Cell Carcinoma of the Head and NeckANTICANCER RESEARCH. Bd. 30. H. 7. 2010 S. 2561-2566
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MGMT activity, promoter methylation and immunohistochemistry of pre-treatment and recurrent malignant gliomasONKOLOGIE. Bd. 33. 2010 S. 6-6
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MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastomaINTERNATIONAL JOURNAL OF CANCER. Bd. 127. H. 9. 2010 S. 2106-2118
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Nijmegen Breakage Syndrome Protein (NBN) Causes Resistance to Methylating Anticancer Drugs Such as TemozolomideMOLECULAR PHARMACOLOGY. Bd. 78. H. 5. 2010 S. 943-951
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Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regenerationPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 107. H. 23. 2010 S. 10371-10376
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Processing of O-6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cyclesCELL CYCLE. Bd. 9. H. 1. 2010 S. 168-178
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Response of pancreatic cancer cells treated with interferon-alpha or beta and co-exposed to ionising radiationINTERNATIONAL JOURNAL OF RADIATION BIOLOGY. Bd. 86. H. 9. 2010 S. 732-741
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Stem cells in chemical carcinogenesisArch Toxicol. Bd. 84. 2010 S. 245-51
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Targeting O (6)-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapyCELLULAR AND MOLECULAR LIFE SCIENCES. Bd. 67. H. 21. 2010 S. 3663-3681
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Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expressionBMC DEVELOPMENTAL BIOLOGY. Bd. 10. 2010 S. -
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The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growthCARCINOGENESIS. Bd. 31. H. 8. 2010 S. 1319-1328
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The p53 status impacts the sensitivity of malignant melanoma cells to the DNA interstrand crosslinking anticancer drug fotemustineNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 72-72
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The TCM drug artesunate induces DNA damage in glioblastoma cellsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 71-71
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The Transcriptional Programme of Contact-InhibitionJOURNAL OF CELLULAR BIOCHEMISTRY. Bd. 110. H. 5. 2010 S. 1234-1243
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Three prime exonuclease 1 (TREX1) is regulated by genotoxic stress and involved in replication mediated repair of DNA damageNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 74-74
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Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damageNUCLEIC ACIDS RESEARCH. Bd. 38. H. 19. 2010 S. 6418-6432
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Topotecan Triggers Apoptosis in p53-Deficient Cells by Forcing Degradation of XIAP and Survivin Thereby Activating Caspase-3-Mediated Bid CleavageJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. Bd. 332. H. 1. 2010 S. 316-325
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Toxicity of the antimalarial artemisinin and its dervativesCRITICAL REVIEWS IN TOXICOLOGY. Bd. 40. H. 5. 2010 S. 405-421
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Translesion bypass by the error-free polymerase Pol-Zeta causes cells to tolerate the alkylating anti-cancer drugs temozolomide and fotemustineNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 73-73
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Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEsDNA Repair (Amst). Bd. 8. H. 1. 2009 S. 72-86
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Circadian rhythms and chemical carcinogenesis: Potential link. An overviewMUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS. Bd. 680. H. 1-2. 2009 S. 83-86
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Cisplatin sensitivity is related to late DNA damage processing and checkpoint control rather than to the early DNA damage responseMUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. Bd. 670. H. 1-2. 2009 S. 32-41
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Development and In Vivo Analysis of a New Generation of Optimized Thio-GTP Analogues for Therapy of IBDGASTROENTEROLOGY. Bd. 136. H. 5. 2009 S. A406-A406
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DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK)J Mol Biol. Bd. 385. H. 5. 2009 S. 1409-21
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Effects of an acute exposure to toluene on the DNA repair activity of the human 8-oxoguanine DNA glycosylase 1 (hOGG1) in healthy subjectsArch Toxicol. Bd. 83. H. 8. 2009 S. 777-84
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FEN1 is Overexpressed in Testis, Lung and Brain Tumors.Anticancer Res. Bd. 29. H. 7. 2009 S. 2453-9
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Genotoxicity investigations on nanomaterias: Methods, preparation and characterization of test material, potential artefacts and liminations-Many questions, some answersMutat Res. Bd. 681. 2009 S. 241-258
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How DNA lesions are turned into powerful killing structures: insights from UV-induced apoptosisMutat Res. Bd. 681. H. 2-3. 2009 S. 197-208
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In vivo fate mapping with SCL regulatory elements identifies progenitors for primitive and definitive hematopoiesis in miceMECHANISMS OF DEVELOPMENT. Bd. 126. H. 10. 2009 S. 863-872
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Influence of aryl hydrocarbon expression and cell survival of mouse hepatoma cells.Toxicology. Bd. 259. H. 3. 2009 S. 91-6
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Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivoRadiother Oncol. Bd. 92. H. 3. 2009 S. 492-9
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p53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removalMol Cancer Res. Bd. 7. H. 2. 2009 S. 237-46
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Role of cAMP in mediating AHR signalingBiochem Pharmacol. Bd. 77. H. 4. 2009 S. 627-41
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Selectivity analysis of protein kinase CK2 inhibitors DMAT, TBB and resorufin in cisplatin-induced stress responsesINTERNATIONAL JOURNAL OF ONCOLOGY. Bd. 35. H. 5. 2009 S. 1151-1157
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Targeting the mevalonate pathway for improved anticancer therapy.Curr Cancer Drug Targets. Bd. 9. H. 5. 2009 S. 626-38
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Temozolomide cells: response related to MGMT, MMR, DSBs, and p53Br J Cancer. Bd. 100. H. 2. 2009 S. 322-33
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The translesion polymerase Rev3L in the tolerance of alkylating anticancer drugsMol Pharmacol. Bd. 76. H. 4. 2009 S. 927-34
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alpha(v)beta(3) Integrin-mediated drug resistance in human laryngeal carcinoma cells is caused by glutathione-dependent elimination of drug-induced reactive oxidative speciesMol Pharmacol. Bd. 74. H. 1. 2008 S. 298-306
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Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling.Toxicol Appl Pharmacol. Bd. 229. H. 1. 2008 S. 20-32
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Artesunate derived from traditional Chinese medicine induces DNA damage and repairCancer Res. Bd. 68. H. 11. 2008 S. 4347-51
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Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regenerationREGENERATIVE MEDICINE. Bd. 3. H. 2. 2008 S. 217-235
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Elevation of XPA protein level in testis tumor cells without increasing resistance to cisplatin or UV radiation.Mol Carcinog. Bd. 47. H. 8. 2008 S. 580-6
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Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and RepairCELL. Bd. 135. H. 6. 2008 S. 1118-1129
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Improved models for animal researchHumana Press 2008 17 S.
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Infrequent promoter methylation of the MGMT gene in liver metastases from uveal melanoma.Int J Cancer. Bd. 123. H. 5. 2008 S. 1215-8
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Kinetics of gamma-H2AX focus formation upon treatment of cells with UV light and alkylating agentsEnviron Mol Mutagen. Bd. 49. H. 9. 2008 S. 734-40
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MGMT in primary and recurrent human glioblastomas after radiation and chemotherapy and comparison with p53 status and clinical outcome.Int J Cancer. Bd. 122. H. 6. 2008 S. 1391-9
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Microarray-based expression of DNA repair genes does not correlate with growth inhibition of cancer cells by natural products derived from traditional Chinese medicine.Cancer Genomics Proteomics. Bd. 5. H. 2. 2008 S. 79-84
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New aspects on mechanisms of chemical carcinogenesis: emphasis on species and gender/sex differences and developmental/aging determinantsArch Toxicol. Bd. 82. H. 11. 2008 S. 875-80
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P38 MAP kinase signaling is required for the conversion of CD4+CD25 iTreg.PLoS One. Bd. 3. H. 10. 2008 S. e3302
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Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells.Mol Cancer Ther. Bd. 7. H. 1. 2008 S. 152-61
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Rechallenge with temozolomide with different scheduling is effective in recurrent malignant gliomasMol Med Report. 2008 S. 863-867
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Role of transporter genes in cisplatin resistance.In Vivo. Bd. 22. H. 3. 2008 S. 279-83
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TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin AOncogene. Bd. 27. H. 15. 2008 S. 2198-207