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Forschungszentrum für Immuntherapie (FZI)

Forschungsschwerpunkt / Johannes Gutenberg-Universität Mainz

Publikationen
Ergebnisse pro Seite:  100


Boesl, Fabian; Goereci, Yasemin; Schweitzer, Finja et al.

Cognitive decline in post-COVID-19 syndrome does not correspond with persisting neuronal or astrocytic damage

SCIENTIFIC REPORTS. Bd. 14. H. 1. 2024


Ritter, Katharina; Somnuke, Pawit; Hu, Lingjiao et al.

Current state of neuroprotective therapy using antibiotics in human traumatic brain injury and animal models

BMC NEUROSCIENCE. Bd. 25. H. 1. 2024



Caenepeel, Clara; Falony, Gwen; Machiels, Kathleen et al.

Dysbiosis and Associated Stool Features Improve Prediction of Response to Biological Therapy in Inflammatory Bowel Disease

GASTROENTEROLOGY. Bd. 166. H. 3. 2024 S. 483-495


Mikulicic, Snjezana; Shamun, Merha; Massenberg, Annika et al.

ErbB2/HER2 receptor tyrosine kinase regulates human papillomavirus promoter activity

FRONTIERS IN IMMUNOLOGY. Bd. 15. 2024


Deleu, S.; Caenepeel, C.; Castellanos, J. F. Vazquez et al.

Faecal microbiota transplantation in active Ulcerative Colitis: Key lessons from a randomized controlled trial halted for futility

JOURNAL OF CROHNS & COLITIS. Bd. 18. 2024 S. I158-I159


Lang, Franziska; Schroers, Barbara; Loewer, Martin et al.

Identification of neoantigens for individualized therapeutic cancer vaccines (vol 21, pg 261, 2022)

NATURE REVIEWS DRUG DISCOVERY. Bd. 23. H. 2. 2024 S. 156-156


Dhillon-LaBrooy, Ayesha; Braband, Kathrin L.; Tantawy, Eshraq et al.

Inhibition of Mitochondrial Translation Ameliorates Imiquimod-Induced Psoriasis-Like Skin Inflammation by Targeting Vy4D y8 T Cells

JOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 144. H. 4. 2024


Leypoldt, Lisa B.; Tichy, Diana; Besemer, Britta et al.

Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone for the Treatment of High-Risk Newly Diagnosed Multiple Myeloma

JOURNAL OF CLINICAL ONCOLOGY. Bd. 42. H. 1. 2024 S. 26-+


Schraad, Muriel; Runkel, Stefan; Hitzler, Walter et al.

Long-Term Observation of SARS-CoV-2 Vaccination Response upon High Efficacy Treatment in Multiple Sclerosis-A Real-World Scenario

VACCINES. Bd. 12. H. 3. 2024


Schaller-Paule, Martin A.; Maiworm, Michelle; Schaefer, Jan Hendrik et al.

Matching proposed clinical and MRI criteria of aggressive multiple sclerosis to serum and cerebrospinal fluid markers of neuroaxonal and glial injury

JOURNAL OF NEUROLOGY. 2024



Jakimovski, Dejan; Bittner, Stefan; Zivadinov, Robert et al.

Multiple sclerosis

LANCET. Bd. 403. H. 10422. 2024 S. 183-202



Kansy, Anita G.; Ashry, Ramy; Mustafa, Al-Hassan M. et al.

Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells

MOLECULAR ONCOLOGY. 2024


Heine, Annkristin; Lemmermann, Niels A. W.; Flores, Chrystel et al.

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

FRONTIERS IN IMMUNOLOGY. Bd. 15. 2024


Weyer, Marc-Philipp; Strehle, Jenny; Schaefer, Michael K. E. et al.

Repurposing of pexidartinib for microglia depletion and renewal

PHARMACOLOGY & THERAPEUTICS. Bd. 253. 2024


Felten, Matthias; Distler, Ute; von Wiegen, Nele et al.

Substrate profiling of the metalloproteinase ovastacin uncovers specific enzyme-substrate interactions and discloses fertilization-relevant substrates

FEBS JOURNAL. Bd. 291. H. 1. 2024 S. 114-131


Delacher, Michael; Schmidleithner, Lisa; Simon, Malte et al.

The effector program of human CD8 T cells supports tissue remodeling

JOURNAL OF EXPERIMENTAL MEDICINE. Bd. 221. H. 2. 2024



Kramer, Elliot D.; Tzetzo, Stephanie L.; Colligan, Sean H. et al.

?-Catenin signaling in alveolar macrophages enhances lung metastasis a mechanism

JCI INSIGHT. Bd. 8. H. 8. 2023


Damasceno, Luis Eduardo Alves; Cunha, Thiago Mattar; Cunha, Fernando Queiroz et al.

A clinically-relevant STING agonist restrains human TH17 cell inflammatory profile

INTERNATIONAL IMMUNOPHARMACOLOGY. Bd. 124. 2023


Kadioglu, Onat; Bahramimehr, Faranak; Dawood, Mona et al.

A drug repurposing approach for individualized cancer therapy based on transcriptome sequencing and virtual drug screening

COMPUTERS IN BIOLOGY AND MEDICINE. Bd. 157. 2023


Anyaegbunam, Uchenna Alex; More, Piyush; Fontaine, Jean-Fred et al.

A Systematic Review of Lipid-Focused Cardiovascular Disease Research: Trends and Opportunities

CURRENT ISSUES IN MOLECULAR BIOLOGY. Bd. 45. H. 12. 2023 S. 9904-9916


Leite, Jefferson Antonio; Menezes, Luisa; Martins, Eloisa et al.

AIM2 promotes T<sub>H</sub>17 cells differentiation by regulating RORγt transcription activity

ISCIENCE. Bd. 26. H. 11. 2023


Cox, Eva-Maria; El-Behi, Mohamed; Ries, Stefanie et al.

AKT activity orchestrates marginal zone B cell development in mice and humans

CELL REPORTS. Bd. 42. H. 4. 2023



Tenaglia, Albano H. H.; Lujan, Lucas A. A.; Rios, Diego N. N. et al.

Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia

NATURE COMMUNICATIONS. Bd. 14. H. 1. 2023


Lutfullin, Isabel; Eveslage, Maria; Bittner, Stefan et al.

Association of obesity with disease outcome in multiple sclerosis

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. Bd. 94. H. 1. 2023 S. 57-61


Timaru-Kast, Ralph; Coronel-Castello, Shila P.; Kraemer, Tobias J. et al.

AT 1 inhibition mediated neuroprotection after experimental traumatic brain injury is dependent on neutrophils in male mice

SCIENTIFIC REPORTS. Bd. 13. H. 1. 2023


Pape, Katrin; Protopapa, Maria; Schraad, Muriel et al.

Case Report: Balancing immune responses - multiple sclerosis disease exacerbation under BRAF/MEK treatment for malignant melanoma

FRONTIERS IN ONCOLOGY. Bd. 13. 2023


Backer, Ronald A.; Probst, Hans Christian; Clausen, Bjoern E.

Classical DC2 subsets and monocyte-derived DC: Delineating the developmental and functional relationship

EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 53. H. 3. 2023


Sassmannshausen, Juliane; Bennink, Sandra; Distler, Ute et al.

Comparative proteomics of vesicles essential for the egress of<i> Plasmodium</i><i> falciparum</i> gametocytes from red blood cells

MOLECULAR MICROBIOLOGY. 2023




Lakus, J.; Backer, R. A.; Eich, C. et al.

Constitutive stabilization of beta-catenin in CD11c+cells alleviates allergic asthma

ALLERGOLOGIE. Bd. 46. H. 2. 2023 S. 135-135


Bukur, Thomas; Riesgo-Ferreiro, Pablo; Sorn, Patrick et al.

CoVigator-A Knowledge Base for Navigating SARS-CoV-2 Genomic Variants

VIRUSES-BASEL. Bd. 15. H. 6. 2023


Kamenjarin, Nadine; Hodapp, Katrin; Melchior, Felix et al.

Cross- presenting Langerhans cells are required for the early reactivation of resident CD8+memory T cells in the epidermis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 120. H. 34. 2023


Zipp, Frauke; Bittner, Stefan; Schafer, Dorothy P.

Cytokines as emerging regulators of central nervous system synapses

IMMUNITY. Bd. 56. H. 5. 2023 S. 914-925


Bersching, Katharina; Michna, Thomas; Tenzer, Stefan et al.

Data-Independent Acquisition (DIA) Is Superior for High Precision Phospho-Peptide Quantification in Magnaporthe oryzae

JOURNAL OF FUNGI. Bd. 9. H. 1. 2023


Kriege, Oliver; Kreft, Andreas; Hauptrock, Beate et al.

Diagnosis of sinusoidal obstruction syndrome: can biopsy be the key?

ANNALS OF HEMATOLOGY. 2023


Zevallos, Victor F.; Yogev, Nir; Hauptmann, Judith et al.

Dietary wheat amylase trypsin inhibitors exacerbate CNS inflammation in experimental multiple sclerosis

GUT. 2023



Krolevets, Mykhailo; ten Cate, Vincent; Prochaska, Juergen H. et al.

DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites

CLINICAL EPIGENETICS. Bd. 15. H. 1. 2023



Kraemer, Tobias J.; Pickart, Florian; Poettker, Bruno et al.

Early DNase-I therapy delays secondary brain damage after traumatic brain injury in adult mice

SCIENTIFIC REPORTS. Bd. 13. H. 1. 2023


Gross, Catharina C.; Schulte-Mecklenbeck, Andreas; Steinberg, Olga et al.

Early multiple sclerosis is characterized by three discrete immunological endophenotypes in the blood predicting distinct disease trajectories and treatment responses

MULTIPLE SCLEROSIS JOURNAL. Bd. 29. 2023 S. 139-141


Barth, Kathrin; Vasic, Verica; McDonald, Brennan et al.

EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory

CELLULAR AND MOLECULAR LIFE SCIENCES. Bd. 80. H. 2. 2023


Barth, Kathrin; Vasic, Verica; McDonald, Brennan et al.

EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory (vol 80, 54, 2023)

CELLULAR AND MOLECULAR LIFE SCIENCES. Bd. 80. H. 8. 2023


Rausch, Johanna; Ullrich, Evelyn; Kuehn, Michael W. M.

Epigenetic targeting to enhance acute myeloid leukemia-directed immunotherapy

FRONTIERS IN IMMUNOLOGY. Bd. 14. 2023



Andrikopoulos, Petros; Aron-Wisnewsky, Judith; Chakaroun, Rima et al.

Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine <i>N</i>-oxide

NATURE COMMUNICATIONS. Bd. 14. H. 1. 2023


Protopapa, Maria; Samarin, Jana; Brummer, Tobias et al.

Exploring the impact of a self-guided online intervention approach on fatigue in people with Multiple Sclerosis

MULTIPLE SCLEROSIS JOURNAL. Bd. 29. 2023 S. 388-388


Riehl, Dennis R.; Sharma, Arjun; Roewe, Julian et al.

Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 120. H. 40. 2023


Salmen, Anke; Hoepner, Robert; Fleischer, Vinzenz et al.

Factors associated with depressive mood at the onset of multiple sclerosis - an analysis of 781 patients of the German NationMS cohort

THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS. Bd. 16. 2023


Gastaldi, Vinicius Daguano; Wilke, Justus B. H.; Weidinger, Cosima A. et al.

Factors predisposing to humoral autoimmunity against brain-antigens in health and disease: <i>Analysis of 49 autoantibodies in over 7000 subjects</i>

BRAIN BEHAVIOR AND IMMUNITY. Bd. 108. 2023 S. 135-147


Deleu, S.; Caenepeel, C.; Verstockt, S. et al.

FMT in UC is associated with a decrease in Bacteroides-2 enterotype and response with baseline RNA and microbiota signatures

JOURNAL OF CROHNS & COLITIS. Bd. 17. 2023 S. 1029-1030



Engel, Sinah; Hildesheim, Leonore; Fleischer, Vinzenz et al.

Genetic contributions to white matter lesion volume in multiple sclerosis

MULTIPLE SCLEROSIS JOURNAL. Bd. 29. 2023 S. 805-806


Gomez-Zepeda, David; Michna, Thomas; Ziesmann, Tanja et al.

HowDirty: An R package to evaluate molecular contaminants in LC-MS experiments

PROTEOMICS. 2023



Gross, Catharina C.; Schulte-Mecklenbeck, Andreas; Steinberg, Olga V. et al.

Identification of multiple sclerosis endophenotypes by high dimensional blood signatures associated with distinct disease trajectories

NEUROLOGY. Bd. 100. H. 17. 2023


Volkmar, Michael; Fakhr, Elham; Zens, Stefan et al.

Identification of TRDV-TRAJ V domains in human and mouse T-cell receptor repertoires

FRONTIERS IN IMMUNOLOGY. Bd. 14. 2023


Bittner, Stefan; Zipp, Frauke

IL-17 receptor goes solo in autoimmune inflammation

IMMUNITY. Bd. 56. H. 9. 2023 S. 1977-1980


Brabec, Tomas; Vobonl, Matous; Schierova, Dagmar et al.

IL-17-driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum

MUCOSAL IMMUNOLOGY. Bd. 16. H. 4. 2023 S. 373-385


Guedes, Joana R.; Ferreira, Pedro A.; Costa, Jessica et al.

IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development

NEURON. Bd. 111. H. 21. 2023 S. 3435-3449


Lutz, Veronika; Hellmund, Veronique M.; Picard, Felix S. R. et al.

IL18 Receptor Signaling Regulates Tumor-Reactive CD8<SUP>+</SUP> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

CANCER IMMUNOLOGY RESEARCH. Bd. 11. H. 4. 2023 S. 421-434


Moos, S.; Mohebiany, A. N.; Waisman, A. et al.

Imiquimod-induced psoriasis-like dermatitis in mice depends on IL-17 signaling of keratinocytes

EXPERIMENTAL DERMATOLOGY. Bd. 32. H. 4. 2023 S. E26-E26



Lordick, Florian; Thuss-Patience, Peter; Bitzer, Michael et al.

Immunological effects and activity of multiple doses of zolbetuximab in combination with zoledronic acid and interleukin-2 in a phase 1 study in patients with advanced gastric and gastroesophageal junction cancer

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. Bd. 149. H. 9. 2023 S. 5937-5950


Krenzlin, Viola; Schoche, Johannes; Walachowski, Sarah et al.

Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates

EUROPEAN JOURNAL OF IMMUNOLOGY. 2023


Tubio-Santamaria, Nuria; Jayavelu, Ashok Kumar; Schnoeder, Tina M. et al.

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

MOLECULAR CANCER. Bd. 22. H. 1. 2023



Schuckmann, Aaron; Steffen, Falk; Zipp, Frauke et al.

Impact of extended interval dosing of ocrelizumab on immunoglobulin levels in multiple sclerosis

MED. Bd. 4. H. 6. 2023 S. 361-+


Mai, Elias K.; Huhn, Stefanie; Miah, Kaya et al.

Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma

BLOOD CANCER JOURNAL. Bd. 13. H. 1. 2023


Bittner, Stefan; Pape, Katrin; Klotz, Luisa et al.

Implications of immunometabolism for smouldering MS pathology and therapy

NATURE REVIEWS NEUROLOGY. Bd. 19. H. 8. 2023 S. 477-488


Pradhan, Rashmita; Becker, Lukas-Sebastian; Schulz-Kuhnt, Anja et al.

INFLAMMATION-ASSOCIATED MODULATION OF THE MEVALONATE PATHWAY IN THE INTESTINAL EPITHELIUM; A LINK BETWEEN PRENYLATION AND GUT TISSUE HOMEOSTASIS

GASTROENTEROLOGY. Bd. 164. H. 6. 2023 S. S230-S230




Gaertner, Yvonne; Bitar, Lynn; Zipp, Frauke et al.

Interleukin-4 as a therapeutic target

PHARMACOLOGY & THERAPEUTICS. Bd. 242. 2023


Kotsiliti, Elena; Leone, Valentina; Schuehle, Svenja et al.

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

JOURNAL OF HEPATOLOGY. Bd. 79. H. 2. 2023 S. 296-+


Teschner, David; Gomez-Zepeda, David; Declercq, Arthur et al.

Ionmob: a Python package for prediction of peptide collisional cross-section values

BIOINFORMATICS. Bd. 39. H. 9. 2023


Brand, Anna; Hovav, Avi-Hai; Clausen, Bjorn E.

Langerhans cells in the skin and oral mucosa: Brothers in arms?

EUROPEAN JOURNAL OF IMMUNOLOGY. 2023


Harroud, Adil; Stridh, Pernilla J.; McCauley, Jacob H. et al.

Locus for severity implicates CNS resilience in progression of multiple sclerosis

NATURE. Bd. 619. H. 7969. 2023 S. 329-331


Schraad, Muriel; Uphaus, Timo; Bittner, Stefan et al.

Long-term observation of SARS-CoV-2 vaccination response in multiple sclerosis in a real world scenario

MULTIPLE SCLEROSIS JOURNAL. Bd. 29. 2023 S. 619-619


Schroers, Barbara; Hos, Brett J.; Yildiz, Ikra G. et al.

MC38 colorectal tumor cell lines from two different sources display substantial differences in transcriptome, mutanome and neoantigen expression

FRONTIERS IN IMMUNOLOGY. Bd. 14. 2023



Santisteban, Monica M.; Schaeffer, Samantha; Anfray, Antoine et al.

Meningeal interleukin-17-producing T cells mediate cognitive impairment in a mouse model of salt-sensitive hypertension

NATURE NEUROSCIENCE. 2023


Fleischer, Vinzenz; Brummer, Tobias; Muthuraman, Muthuraman et al.

Multimodal biomarker combinations predict disease activity and progression over 4 years in early multiple sclerosis

MULTIPLE SCLEROSIS JOURNAL. Bd. 29. 2023 S. 322-323


Lang, Franziska; Sorn, Patrick; Schroers, Barbara et al.

Multiple instance learning to predict immune checkpoint blockade efficacy using neoantigen candidates

ISCIENCE. Bd. 26. H. 11. 2023


Ringen, Julia; Schaller, Theresa; Fischer, Berenice et al.

MYELOID CELL-DERIVED REACTIVE OXYGEN SPECIES FROM LESIONAL SKIN CONTRIBUTE TO VASCULAR INFLAMMATION IN EXPERIMENTAL PSORIASIS

FREE RADICAL BIOLOGY AND MEDICINE. Bd. 201. 2023 S. 7-7


Bueno, Diones; Dey, Partha Narayan; Schacht, Teresa et al.

NECAB2 is an endosomal protein important for striatal function

FREE RADICAL BIOLOGY AND MEDICINE. Bd. 208. 2023 S. 643-656


Bersano, A.; Engele, J.; Schafer, M. K. E.

Neuroinflammation and Brain Disease

BMC NEUROLOGY. Bd. 23. H. 1. 2023


Schlegelmilch, Anna-Lena; Schillner, Miriam; Zipp, Frauke et al.

Neuronal intracellular calcium storage release upon direct T-cell-neuron interaction

MULTIPLE SCLEROSIS JOURNAL. Bd. 29. 2023 S. 497-498


Giampaolo, Sabrina; Chiarolla, Cristina M.; Knoepper, Konrad et al.

NFATc1 induction by an intronic enhancer restricts NKT yδ cell formation

ISCIENCE. Bd. 26. H. 3. 2023


Marinovic, Sonja; Lenartic, Maja; Mladenic, Karlo et al.

NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis

SCIENCE IMMUNOLOGY. Bd. 8. H. 87. 2023


Marinovic, Sonja; Lenartic, Maja; Mladenic, Karlo et al.

NKG2D-mediated immunosensing of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis

EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 53. 2023 S. 17-17


Hartmann, Ann-Kathrin; Bartneck, Joschka; Pielenhofer, Jonas et al.

Optimized dithranol-imiquimod-based transcutaneous immunization enables tumor rejection

FRONTIERS IN IMMUNOLOGY. Bd. 14. 2023


Sonneveld, Pieter; Chanan-Khan, Asher; Weisel, Katja et al.

Overall Survival With Daratumumab, Bortezomib, and Dexamethasone in Previously Treated Multiple Myeloma (CASTOR): A Randomized, Open-Label, Phase III Trial

JOURNAL OF CLINICAL ONCOLOGY. Bd. 41. H. 8. 2023 S. 1600-+