Forschungszentrum für Immuntherapie (FZI)
Forschungsschwerpunkt / Johannes Gutenberg-Universität Mainz
Hess, Georg; Huettmann, Andreas; Witzens-Harig, Mathias et al.
A phase II trial to evaluate the combination of pixantrone and obinutuzumab for patients with relapsed aggressive lymphoma: Final results of the prospective, multicentre GOAL trialBRITISH JOURNAL OF HAEMATOLOGY. 2022
Machowicz, Rafal; Suarez, Felipe; Wiktor-Jedrzejczak, Wieslaw et al.
Allogeneic hematopoietic stem cell transplantation for adult HLH: a retrospective study by the chronic malignancies and inborn errors working parties of EBMTBONE MARROW TRANSPLANTATION. 2022
Gatsiou, A.; Bonini, F.; Vlachogiannis, N. et al.
An endothelial-specific epitranscriptional checkpoint of IL-6 trans-signaling controls leukocyte trafficking in ischemic heart tissuesEUROPEAN JOURNAL OF HEART FAILURE. Bd. 24. 2022 S. 7-7
El Hamdaoui, Yamina; Zheng, Fang; Fritz, Nikolas et al.
Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugsMOLECULAR PSYCHIATRY. 2022
Xia, N.; Hasselwander, S.; Reifenberg, G. et al.
B LYMPHOCYTE-DEFICIENCY IN MICE CAUSES VASCULAR DYSFUNCTION BY INDUCING NEUTROPHILIAATHEROSCLEROSIS. Bd. 355. 2022 S. E112-E113
Bednarczyk, Monika; Bolduan, Vanessa; Haist, Maximilian et al.
beta 2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune EncephalomyelitisCELLS. Bd. 11. H. 14. 2022
Yogev, Nir; Bedke, Tanja; Kobayashi, Yasushi et al.
CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survivalCELL REPORTS. Bd. 38. H. 13. 2022
Ludwig, Katharina; Huppertz, Tilman; Radsak, Markus et al.
Cellular Immune Dysfunction in Obstructive Sleep ApneaFRONTIERS IN SURGERY. Bd. 9. 2022
Zhang, Jianxi; Cheng, Zhigang; Tian, Ying et al.
Cerebral Tissue Oxygen Saturation Correlates with Emergence from Propofol-Remifentanil Anesthesia: An Observational Cohort StudyJOURNAL OF CLINICAL MEDICINE. Bd. 11. H. 16. 2022
Zepp, Fred; Berner, Reinhard; Hansen, Gesine et al.
Current projects in healthcare-oriented pediatric researchMONATSSCHRIFT KINDERHEILKUNDE. Bd. 170. H. 5. 2022 S. 375-378
Hamdan, Sara; Reddehase, Matthias J.; Holtappels, Rafaela
Cytomegalovirus immune evasion sets the functional avidity threshold for protection by CD8 T cellsMEDICAL MICROBIOLOGY AND IMMUNOLOGY. 2022
Forchert, Leandra; Potapova, Ekaterina; Panetta, Valentina et al.
Der p 23-specific IgE response throughout childhood and its association with allergic disease: A birth cohort studyPEDIATRIC ALLERGY AND IMMUNOLOGY. Bd. 33. H. 7. 2022
Sohl, Julian; Hartmann, Ann-Kathrin; Hahlbrock, Jennifer et al.
Dithranol as novel co-adjuvant for non-invasive dermal vaccinationNPJ VACCINES. Bd. 7. H. 1. 2022
Wang, Yong; Wernersbach, Isa; Strehle, Jenny et al.
Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in miceBRAIN BEHAVIOR AND IMMUNITY. Bd. 106. 2022 S. 49-66
Kostka, Susanna Lopez; Kautz-Neu, Kordula; Yogev, Nir et al.
Exclusive Expression of MyD88 on Dendritic Cells Is Sufficient to Induce Protection against Experimental LeishmaniasisJOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 142. H. 4. 2022 S. 1230-+
Zhang, Yu; Yang, Xin; Hou, Xinran et al.
Extracellular signal-regulated kinase-dependent phosphorylation of histone H3 serine 10 is involved in the pathogenesis of traumatic brain injuryFRONTIERS IN MOLECULAR NEUROSCIENCE. Bd. 15. 2022
Wolf, Christina; Pouya, Alireza; Bitar, Sara et al.
GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeletonCOMMUNICATIONS BIOLOGY. Bd. 5. H. 1. 2022
Gehrke, Nadine; Hofmann, Lea J.; Straub, Beate K. et al.
Hepatic interleukin-1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver diseaseCLINICAL AND TRANSLATIONAL MEDICINE. Bd. 12. H. 9. 2022
Gehrke, Nadine; Woerns, Marcus A.; Mann, Amrit et al.
Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failureCELL DEATH & DISEASE. Bd. 13. H. 5. 2022
Becker, Sara; Fink, Annette; Podlech, Juergen et al.
Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune EvasionVIRUSES-BASEL. Bd. 14. H. 1. 2022
Zinina, Valeriya V.; Ruehle, Frank; Winkler, Patricia et al.
ID2 controls differentiation of enteroendocrine cells in mouse small intestineACTA PHYSIOLOGICA. Bd. 234. H. 2. 2022
Kaps, Leonard; Schleicher, Eva Maria; Montano, Carolina Medina et al.
Influence of Advanced Organ Support (ADVOS) on Cytokine Levels in Patients with Acute-on-Chronic Liver Failure (ACLF)JOURNAL OF CLINICAL MEDICINE. Bd. 11. H. 10. 2022
Aksan, Ayseguel; Zepp, Fred; Anand, Sangeetha et al.
Intravenous ferric carboxymaltose for the management of iron deficiency and iron deficiency anaemia in children and adolescents: a reviewEUROPEAN JOURNAL OF PEDIATRICS. 2022
Thoelmann, Sonja; Seebach, Jochen; Otani, Tetsuhisa et al.
JAM-A interacts with alpha 3 beta 1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cellsCELLULAR AND MOLECULAR LIFE SCIENCES. Bd. 79. H. 2. 2022
Ruck, Tobias; Bock, Stefanie; Pfeuffer, Steffen et al.
K(2P)18.1 translates T cell receptor signals into thymic regulatory T cell developmentCELL RESEARCH. Bd. 32. H. 1. 2022 S. 72-88
Wirsching, Sebastian; Harder, Laura; Heymanns, Markus et al.
Long-Term, CD4(+) Memory T Cell Response to SARS-CoV-2FRONTIERS IN IMMUNOLOGY. Bd. 13. 2022
Becker, Sara; Reddehase, Matthias J.; Lemmermann, Niels A.
Mast Cells Meet Cytomegalovirus: A New Example of Protective Mast Cell Involvement in an Infectious DiseaseCELLS. Bd. 11. H. 9. 2022
Blanco-Perez, Frank; Gonzalez-Menendez, Irene; Stassen, Michael et al.
Mast cells partly contribute to allergic enteritis development: Findings in two different mast cell-deficient miceALLERGY. Bd. 77. H. 3. 2022 S. 1051-1054
Klopp, Jonas; Ferretti, Pamela; Meyer, Claudius U. et al.
Meconium Microbiome of Very Preterm Infants across GermanyMSPHERE. Bd. 7. H. 1. 2022
Klopp, Jonas; Ferretti, Pamela; Meyer, Claudius U. et al.
Meconium Microbiome of Very Preterm Infants across GermanyMSPHERE. Bd. 7. H. 1. 2022
Holtappels, Rafaela; Podlech, Juergen; Freitag, Kirsten et al.
Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus SpreadVIRUSES-BASEL. Bd. 14. H. 6. 2022
Cacicedo, Maximiliano L.; Weinl-Tenbruck, Christine; Frank, Daniel et al.
mRNA-based therapy proves superior to the standard of care for treating hereditary tyrosinemia 1 in a mouse modelMOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. Bd. 26. 2022 S. 294-308
Medina-Montano, Carolina; Rivero Berti, Ignacio; Gambaro, Rocio C. et al.
Nanostructured Lipid Carriers Loaded with Dexamethasone Prevent Inflammatory Responses in Primary Non-Parenchymal Liver CellsPHARMACEUTICS. Bd. 14. H. 8. 2022
Mattos, Matheus; Vandendriessche, Sofie; Schuermans, Sara et al.
Natural antibodies are required for necrotic cell debris clearance and liver repair during necrotic liver injuryJOURNAL OF HEPATOLOGY. Bd. 77. 2022 S. S396-S397
Haist, Maximilian; Ries, Frederic; Gunzer, Matthias et al.
Neutrophil-Specific Knockdown of beta 2 Integrins Impairs Antifungal Effector Functions and Aggravates the Course of Invasive Pulmonal AspergillosisFRONTIERS IN IMMUNOLOGY. Bd. 13. 2022
Hoevelmeyer, Nadine; Schmidt-Supprian, Marc; Ohnmacht, Caspar
NF-kappa B in control of regulatory T cell development, identity, and functionJOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 100. H. 7. 2022 S. 985-995
Galetzka, Danuta; Boeck, Julia; Wagner, Lukas et al.
p HYPERMETHYLATION OF RAD9A INTRON 2 IN CHILDHOOD CANCER PATIENTS, LEUKEMIA AND TUMOR CELL LINES SUGGEST A ROLE FOR ONCOGENIC TRANSFORMATIONEXCLI JOURNAL. Bd. 21. 2022 S. 117-143
Hahnefeld, Lisa; Vogel, Alexandra; Gurke, Robert et al.
Phosphatidylethanolamine Deficiency and Triglyceride Overload in Perilesional Cortex Contribute to Non-Goal-Directed Hyperactivity after Traumatic Brain Injury in MiceBIOMEDICINES. Bd. 10. H. 4. 2022
Neuberger, Elmo W. I.; Sontag, Stephanie; Brahmer, Alexandra et al.
Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsyCLINICAL EPIGENETICS. Bd. 14. H. 1. 2022
Sebastiani, Anne; Bender, Simone; Schaefer, Michael K. E. et al.
Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injuryBMC ANESTHESIOLOGY. Bd. 22. H. 1. 2022
Kraemer, Tobias J.; Huebener, Per; Poettker, Bruno et al.
Ribonuclease-1 treatment after traumatic brain injury preserves blood-brain barrier integrity and delays secondary brain damage in miceSCIENTIFIC REPORTS. Bd. 12. H. 1. 2022
Tilch, Marie-Kristin; Robak, Tadeusz; Ghiggi, Chiara et al.
Safety of the Anti-CD19 antibody Tafasitamab in Long Term Responders from A Phase II Trial for Relapsed LymphomaCLINICAL LYMPHOMA MYELOMA & LEUKEMIA. Bd. 22. H. 4. 2022 S. 270-275
Heo, Dongeun; Ling, Jonathan P.; Molina-Castro, Gian C. et al.
Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43ELIFE. Bd. 11. 2022
Murray, Mallory Paynich; Crosby, Catherine M.; Marcovecchio, Paola et al.
Stimulation of a subset of natural killer T cells by CD103(+) DC is required for GM-CSF and protection from pneumococcal infectionCELL REPORTS. Bd. 38. H. 2. 2022
Stickdorn, Judith; Stein, Lara; Arnold-Schild, Danielle et al.
Systemically Administered TLR7/8 Agonist and Antigen-Conjugated Nanogels Govern Immune Responses against TumorsACS NANO. Bd. 16. H. 3. 2022 S. 4426-4443
Arendholz, L. T.; Schwingen, J.; Freund, L. et al.
The G-protein coupled receptor EBI2 is involved in the pathogenesis of murine TNCB-induced contact hypersensitivityEXPERIMENTAL DERMATOLOGY. Bd. 31. H. 2. 2022 S. E53-E54
Ruan, Jing; Schlueter, Dirk; Naumann, Michael et al.
Ubiquitin-modifying enzymes as regulators of colitisTRENDS IN MOLECULAR MEDICINE. Bd. 28. H. 4. 2022 S. 304-318
Engel, Sinah; Galindo, Lara S. Molina; Bittner, Stefan et al.
A Case of Progressive Multifocal Leukoencephalopathy in a Fumaric Acid-Treated Psoriasis Patient With Severe Lymphopenia Among Other Risk FactorsJOURNAL OF CENTRAL NERVOUS SYSTEM DISEASE. Bd. 13. 2021
Bittner, Stefan; Zipp, Frauke
A lymphocyte-glia connection sets the pace for smoldering inflammationCELL. Bd. 184. H. 23. 2021 S. 5696-5698
Krienke, Christina; Kolb, Laura; Diken, Elif et al.
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitisSCIENCE. Bd. 371. H. 6525. 2021