Forschungszentrum für Immuntherapie (FZI)
Forschungsschwerpunkt / Johannes Gutenberg-Universität Mainz
Hurry, Madeleine; Posner, David A.; Wong, Raymond et al.
Cerebral ischaemic stroke results in altered mucosal antibody responses and host-commensal microbiota interactionsBRAIN BEHAVIOR AND IMMUNITY. Bd. 131. 2026
Schmitt, Fabian; Ten Cate, Vincent; Fischer, Zlatka et al.
Metabolic Profiling of the EmDia Cohort by LC-MS Reveals Empagliflozin-Intake Associated Regulation of 1,5-anhydroglucitol and UratePROTEOMICS. Bd. 26. H. 1. 2026 S. 44-56
Zou, Chengyu; Li, Peiying; Li, Bin et al.
Next steps in regulatory T cells Biology and clinical applicationCELL. Bd. 189. H. 1. 2026 S. 6-22
Ritter, Katharina; Petri, Katharina; Denninger, Julian et al.
Prolonged antibiotic treatment accelerates neurological recovery and reduces long-term neuroinflammatory gene expression after experimental TBI in miceEXPERIMENTAL NEUROLOGY. Bd. 398. 2026
Weyer, Marc-Philipp; Hahnefeld, Lisa; Franck, Luisa et al.
Selective neuronal restoration of progranulin does not prevent the frontotemporal dementia like-phenotype of progranulin knockout miceJOURNAL OF NEUROINFLAMMATION. Bd. 23. H. 1. 2026
Perner, Florian; Berg, Tobias; Sasca, Daniel et al.
Therapeutic targeting of chromatin alterations in leukemia and solid tumorsINTERNATIONAL JOURNAL OF CANCER. Bd. 158. H. 2. 2026 S. 382-408
Toelle, Daniela; Ferner, Marion; Mai, Sandra Stephanie et al.
"Accompanying the dying process": A guide to dealing with the dying and their relativesDEUTSCHE MEDIZINISCHE WOCHENSCHRIFT. Bd. 150. H. 14. 2025 S. 807-816
Frenking, Jan H.; Riedhammer, Christine; Teipel, Raphael et al.
A German multicenter real-world analysis of talquetamab in 138 patients with relapsed/refractory multiple myelomaHEMASPHERE. Bd. 9. H. 4. 2025
Hess, Georg; Eyre, Toby A.; Jen, Min-hua et al.
A matching-adjusted indirect comparison of survival outcomes with pirtobrutinib (BRUIN) versus standard of care (SCHOLAR-2) in relapsed/refractory mantle cell lymphoma previously treated with a covalent Bruton tyrosine kinase inhibitorBRITISH JOURNAL OF HAEMATOLOGY. 2025
Roubanis, Aristeidis; Hilaire, Morgane; Le Teuff, Morgane et al.
A new method to measure cell metabolism of rare cells <i>in vivo</i> reveals a high oxidative phosphorylation dependence of lung T cellsIMMUNOLOGY AND CELL BIOLOGY. 2025 S. 15
Stueve, Philipp; Godoy, Gloria J.; Ferreyra, Fernando N. et al.
ACC1 is a dual metabolic-epigenetic regulator of Treg stability and immune toleranceMOLECULAR METABOLISM. Bd. 94. 2025
Shah, Viral; Giotopoulos, George; Osaki, Hikari et al.
Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivationBLOOD. Bd. 145. H. 7. 2025
Huete-Carrasco, Jorge; Zhu, Jingjing; Van den Eynde, Benoit J. et al.
Adsorption of antigen to polymeric nanoparticles enhances cytotoxic T-cell responses and anti-tumor immunity by targeting conventional type 1 dendritic cellsIMMUNOLOGY AND CELL BIOLOGY. 2025
Mykicki, Nadine; Eble, Johannes A.; Weighardt, Heike et al.
AhR signaling in skin-resident CD207+cells is involved in UV-B-induced amelioration of neuroinflammationPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 122. H. 36. 2025
Ahmad, Osama; Kroeger, Nicolaus; Wagner-Drouet, Eva et al.
Allogeneic hematopoietic cell transplantation after infection with SARS-CoV-2 during the COVID-19 pandemic: a multicenter retrospective analysisBONE MARROW TRANSPLANTATION. Bd. 60. H. 5. 2025 S. 733-736
Giebel, Sebastian; Labopin, Myriam; Swoboda, Ryszard et al.
Allogeneic hematopoietic cell transplantation for older patients with Philadelphia-positive acute lymphoblastic leukemia. A study by the Acute Leukemia Working Party of the EBMTBONE MARROW TRANSPLANTATION. Bd. 60. H. 10. 2025 S. 1325-1332
Esteve, Jordi; Nagler, Arnon; Labopin, Myriam et al.
Allogeneic Hematopoietic Cell Transplantation in Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Genetic Features: Relevance of the Genetic Underlying Category. A Retrospective Analysis on Behalf of the Acute Leukemia Working Party of the EBMTAMERICAN JOURNAL OF HEMATOLOGY. Bd. 100. H. 6. 2025 S. 954-962
Peng, Wenwu; Zhou, Tianjiao; Hu, Lifan et al.
Autonomous Activation of a Gated Chemiluminescent Photosensitizer Enables Targeted Photodynamic Therapy in Tumor CellsJOURNAL OF THE AMERICAN CHEMICAL SOCIETY. Bd. 147. H. 31. 2025 S. 27822-27834
Olde Heuvel, Florian; Zhang, Jin; Sun, Fan et al.
Basophils activate splenic B cells and dendritic cells via IL-13 signaling in acute traumatic brain injuryJOURNAL OF NEUROINFLAMMATION. Bd. 22. H. 1. 2025
Maiworm, Michelle; Koerbel, Kimberly; Anschuetz, Victoria et al.
BDNF levels in serum and CSF are associated with clinicoradiological characteristics of aggressive disease in MS patientsJOURNAL OF NEUROLOGY. Bd. 272. H. 2. 2025
Ochs, Jasmin; Schweineberg, Pia; Klein, Matthias et al.
Besides B cells, CD19 is expressed on a fraction of T cells and monocytes, which are concomitantly depleted by anti-CD19 inebilizumabMULTIPLE SCLEROSIS JOURNAL. Bd. 31. H. 3. 2025 S. 1149-1150
Frenking, Jan H.; Zhou, Xiang; Rejeski, Kai et al.
Bridging intensity is associated with impaired hematopoietic recovery after BCMA CAR-T therapy for multiple myelomaBLOOD ADVANCES. Bd. 9. H. 16. 2025 S. 4151-4166
Worel, Nina; Mooyaart, Jarl E.; Hoogenboom, Jorinde D. et al.
CAR-T cell manufacturing failures and out-of-specification products in the real-world setting: A survey from the EBMT cellular therapy and immunobiology working partyBONE MARROW TRANSPLANTATION. Bd. 60. H. 8. 2025 S. 1184-1186
Leypoldt, Lisa B.; Guo, Linlin; Besemer, Britta et al.
Cardiac biomarkers for risk stratification in newly diagnosed high-risk multiple myeloma in the GMMG-CONCEPT trialCARDIO-ONCOLOGY. Bd. 11. H. 1. 2025
Rausch, Johanna; Herold, Stephanie; Liebhauser, Simone et al.
Case Report: Late-onset primary hemophagocytic lymphohistiocytosis leading to the diagnosis of Griscelli syndrome type 2 in a young woman with phenotypically inapparent partial albinismFRONTIERS IN IMMUNOLOGY. Bd. 16. 2025
Denk, Alexander; Fante, Matthias Alexander; Heidenreich, Silke et al.
Changes in Chronic Graft-versus-Host Disease Treatment Over Time: A 15-Years Survey Within Allogeneic Hematopoietic Stem Cell Transplant Centers in Germany, Austria, and SwitzerlandTRANSPLANTATION AND CELLULAR THERAPY. Bd. 31. H. 7. 2025 S. 450e1-450e10
Mandel, Sebastian; Hanke, Thomas; Prendiville, Niall et al.
Covalent Targeting Leads to the Development of a LIMK1 Isoform-Selective InhibitorJOURNAL OF MEDICINAL CHEMISTRY. Bd. 68. H. 14. 2025 S. 15026-15049
Hebbar Subramanyam, Sudheendra; Turyne Hriczko, Judit; Schulz, Saskia et al.
CREB regulates Foxp3<SUP>+</SUP>ST-2<SUP>+</SUP> T<sub>REGS</sub> with enhanced IL-10 productionFRONTIERS IN IMMUNOLOGY. Bd. 16. 2025
Rafei, Hind; Basar, Rafet; Acharya, Sunil et al.
CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cellsNATURE. Bd. 643. H. 8073. 2025
Ahmed, Azaz; Springfeld, Christoph; Halama, Niels
De novo induction of tertiary lymphoid structures: an immunotherapeutic strategy in pancreatic cancerSIGNAL TRANSDUCTION AND TARGETED THERAPY. Bd. 10. H. 1. 2025
Androdias, Geraldine; Luenemann, Jan D.; Maillart, Elisabeth et al.
De-escalating and discontinuing disease-modifying therapies in multiple sclerosisBRAIN. 2025
Penner, Inessa; Kraemer, Nadine; Hirsch, Julia et al.
Deletion of the Human Cytomegalovirus US2 to US11 Gene Family Members Impairs the Type-I Interferon ResponseVIRUSES-BASEL. Bd. 17. H. 3. 2025
Mei, Fuqi; Deng, Deyu; Cao, Zijun et al.
Deubiquitination of RIPK3 by OTUB2 potentiates neuronal necroptosis after ischemic strokeEMBO MOLECULAR MEDICINE. Bd. 17. H. 4. 2025 S. 679-695
Vermeulen, Astrid; Bootsma, Erik; Proost, Sebastian et al.
Dietary convergence induces individual responses in faecal microbiome compositionEGASTROENTEROLOGY. Bd. 3. H. 2. 2025
Stelljes, Matthias; Middeke, Jan Moritz; Bug, Gesine et al.
Disease risk but not remission status determines transplant outcomes in AML: long-term outcomes of the ASAP trialBLOOD. Bd. 146. H. 19. 2025 S. 2293-2305
Roy, Konkonika; Jedrzejewski, Tomasz; Sobocinska, Justyna et al.
Divergent impact of endotoxin priming and endotoxin tolerance on macrophage responses to cancer cellsCELLULAR IMMUNOLOGY. Bd. 411. 2025
Goranovic, Dusan; Jenko, Branko; Ramsak, Barbara et al.
Efficient and Selective Biosynthesis of a Precursor-Directed FK506 Analogue: Paving the Way for Click ChemistryJOURNAL OF NATURAL PRODUCTS. 2025
Buske, Christian; Herold, Michael; Bahar, Nasim et al.
Epidemiology, Real-World Treatment, and Economic Burden of Waldenström Macroglobulinemia: A Comprehensive Analysis Based on Anonymized Claims Data Between 2010 and 2022VALUE IN HEALTH REGIONAL ISSUES. Bd. 50. 2025
Mann, Caroline; Ojak, Gregor; Hyde, Isabel et al.
Epidermal IL-36 and CCL17 Protein Expression Distinguish Palmar Eczema from Palmar PsoriasisJOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 145. H. 12. 2025
Blomain, Erik S.; Soudi, Shaghayegh; Wang, Ziwei et al.
Evolutionary Pressures Shape Undifferentiated Pleomorphic Sarcoma Development and Radiotherapy ResponseCANCER RESEARCH. Bd. 85. H. 6. 2025 S. 1162-1174
Koerbel, Kimberly; Yalachkov, Yavor; Rotter, Tabea et al.
Exploring the Link Between Renal Function Fluctuations Within the Physiological Range and Serum/CSF Levels of NfL, GFAP, tTAU, and UCHL1INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 26. H. 2. 2025
Thomas, Simone; Wermke, Martin; Vucinic, Vladan et al.
First-in-Human Study of MDG1011, a TCR-T Therapy Directed Against HLA-A*02:01-Restricted PRAME Antigen for High-Risk Myeloid and Lymphoid NeoplasmsCANCERS. Bd. 17. H. 18. 2025
Lopetuso, Loris R.; Deleu, Sara; Puca, Pierluigi et al.
Guidance for Fecal Microbiota Transplantation Trials in Ulcerative Colitis: The Second ROME Consensus ConferenceINFLAMMATORY BOWEL DISEASES. 2025 S. 12
Clausen, Bjoern E.; Dudziak, Diana
Guidelines and Advances in Basic and Applied Dendritic Cell BiologyEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 55. H. 4. 2025
Borges-Canha, Marta; Centelles-Lodeiro, Javier; Leite, Ana Rita et al.
Gut dysbiosis is linked to severe steatosis and enhances its diagnostic performance in MASLDEGASTROENTEROLOGY. Bd. 3. H. 3. 2025
Mikulicic, Snjezana; Massenberg, Annika; Doering, Tatjana et al.
HSPG-binding peptide Pep19-2.5 is a potent inhibitor of HPV16 infectionANTIMICROBIAL AGENTS AND CHEMOTHERAPY. Bd. 69. H. 2. 2025
Southern, Rebecca M.; Schmitz, Rebecca L.; Samaniego-Castruita, Daniela et al.
IgM and IgG1 B cell receptors differentially affect B cell fates and dictate the pathogenesis of mature B cell lymphomasSCIENCE ADVANCES. Bd. 11. H. 35. 2025
Denk, Dominic; Ramakrishnan, Mallika; Conche, Claire et al.
IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesisIMMUNITY. Bd. 58. H. 3. 2025 S. 701-715
Cocciardi, Sibylle; Saadati, Maral; Weiss, Nina et al.
Impact of myelodysplasia-related and additional gene mutations in intensively treated patients with <i>NPM1</i>-mutated AMLHEMASPHERE. Bd. 9. H. 1. 2025
Piekarska, Agnieszka; Abouqateb, Mouad; Boreland, William et al.
Improved GVHD-free relapse-free survival when rATG/ATLG is used in allo-HCT from matched sibling donors - an EBMT registry study by the Transplant Complications Working PartyBONE MARROW TRANSPLANTATION. Bd. 60. H. 12. 2025 S. 1574-1583