Forschungszentrum für Immuntherapie (FZI)
Forschungsschwerpunkt / Johannes Gutenberg-Universität Mainz
Engel, Sinah; Protopapa, Maria; Steffen, Falk et al.
Implications of extreme serum neurofilament light chain levels for the management of patients with relapsing multiple sclerosisTHERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS. Bd. 14. 2021
Sabbaghi, Farhad; Ullner, Lorenz; Bohn, Toszka et al.
In Activated Murine Mast Cells, NFATc2 Is Critical for the Production of Autocrine IL-3, Thereby Promoting the Expression of IL-9JOURNAL OF IMMUNOLOGY. Bd. 206. H. 1. 2021 S. 67-76
Gabriel, Matthias; Holtappels, Rafaela
Inactivation of an Enveloped Virus by Immobilized Antimicrobial PeptidesBIOCONJUGATE CHEMISTRY. Bd. 32. H. 12. 2021 S. 2480-2484
Ouedraogo, Oumarou; Rebillard, Rose-Marie; Jamann, Helene et al.
Increased frequency of proinflammatory CD4 T cells and pathological levels of serum neurofilament light chain in adult drug-resistant epilepsyEPILEPSIA. Bd. 62. H. 1. 2021 S. 176-189
Lukas, Dominika; Dietze-Schwonberg, Kirsten; Kautz-Neu, Kordula et al.
Induction of Regulatory T Cells in Leishmania major-Infected BALB/c Mice Does Not Require Langerin plus Dendritic CellsJOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 141. H. 4. 2021 S. 936-938
Stamm, Paul; Sagoschen, Ingo; Weise, Kerstin et al.
Influenza and RSV incidence during COVID-19 pandemic-an observational study from in-hospital point-of-care testingMEDICAL MICROBIOLOGY AND IMMUNOLOGY. Bd. 210. H. 5-6. 2021 S. 277-282
Vonwirth, Verena; Buelbuel, Yagmur; Werner, Anke et al.
Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil GranulocytesFRONTIERS IN IMMUNOLOGY. Bd. 11. 2021
Wegner, J.; Waisman, A.; von Stebut, E.
Injection of immunocytes into mice with psoriatic skin grafts induces lesion flare up, but no systemic diseaseEXPERIMENTAL DERMATOLOGY. Bd. 30. H. 3. 2021 S. E49-E49
Gil-Pulido, Jesus; Amezaga, Nuria; Jorgacevic, Ivana et al.
Interleukin-23 receptor expressing gamma delta T cells locally promote early atherosclerotic lesion formation and plaque necrosis in miceCARDIOVASCULAR RESEARCH. 2021
Xiao, Yin; Qureischi, Musga; Dietz, Lena et al.
Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivityEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 51-51
Xiao, Yin; Qureischi, Musga; Dietz, Lena et al.
Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivityJOURNAL OF EXPERIMENTAL MEDICINE. Bd. 218. H. 1. 2021
Kubota, Noriko; Saito, Akimasa; Tanaka, Ryota et al.
Langerhans Cells Suppress CD8(+) T Cells In Situ during Mucocutaneous Acute Graft-Versus-Host DiseaseJOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 141. H. 5. 2021 S. 1177-+
Engel, Sinah; Jolivel, Valerie; Kraus, Stefan H-P et al.
Laquinimod dampens IL-1 beta signaling and Th17-polarizing capacity of monocytes in patients with MSNEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION. Bd. 8. H. 1. 2021
Kuske, Michael; Floehr, Julia; Yiallouros, Irene et al.
Limited proteolysis by acrosin affects sperm-binding and mechanical resilience of the mouse zona pellucidaMOLECULAR HUMAN REPRODUCTION. Bd. 27. H. 4. 2021
Salomon, Nadja; Selmi, Abderaouf; Grunwitz, Christian et al.
Local radiotherapy and E7 RNA-LPX vaccination show enhanced therapeutic efficacy in preclinical models of HPV16(+) cancerCANCER IMMUNOLOGY IMMUNOTHERAPY. Bd. 71. H. 8. 2021 S. 1975-1988
Blaum, Franziska; Lukas, Dominika; Reddehase, Matthias J. et al.
Localization of Viral Epitope-Specific CD8 T Cells during Cytomegalovirus Latency in the Lungs and Recruitment to Lung Parenchyma by Airway Challenge InfectionLIFE-BASEL. Bd. 11. H. 9. 2021
Dietze-Schwonberg, Kirsten; Lorenz, Beate; Hartmann, Ann-Kathrin et al.
Mast Cell Deficiency Protects Susceptible BALB/c Mice from Progressive Murine Cutaneous LeishmaniasisJOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 141. H. 2. 2021 S. 450-453
Sinitcyn, Pavel; Hamzeiy, Hamid; Soto, Favio Salinas et al.
MaxDIA enables library-based and library-free data-independent acquisition proteomicsNATURE BIOTECHNOLOGY. Bd. 39. H. 12. 2021 S. 1563-+
Brigas, Helena; Ribeiro, Miguel; Coelho, Joana et al.
Meningeal gamma delta T Cells Impact on Cognition in Health and DiseaseBIOLOGICAL PSYCHIATRY. Bd. 89. H. 9. 2021 S. S64-S65
Gehrke, Nadine; Straub, Beate K.; Ruehle, Frank et al.
METABOLIC HEPATOCARCINOGENESIS IS SLOWED IN HEPATOCYTES LACKING IL-1R1HEPATOLOGY. Bd. 74. 2021 S. 1079A-1079A
Luu, Maik; Riester, Zeno; Baldrich, Adrian et al.
Microbial short-chain fatty acids modulate CD8(+) T cell responses and improve adoptive immunotherapy for cancerNATURE COMMUNICATIONS. Bd. 12. H. 1. 2021
Regen, Tommy; Waisman, Ari
Modeling a complex disease: Multiple sclerosis-Update 2020Advances in Immunology. Bd. 149. 2021 S. 25-34
Wiendl, Heinz; Gold, Ralf; Berger, Thomas et al.
Multiple sclerosis treatment consensus group (MSTCG): position paper on disease-modifying treatment of multiple sclerosis 2021 (white paper)NERVENARZT. Bd. 92. H. 8. 2021 S. 773-801
Lang, Franziska; Ferreiro, Pablo Riesgo; Loewer, Martin et al.
NeoFox: annotating neoantigen candidates with neoantigen featuresBIOINFORMATICS. Bd. 37. H. 22. 2021 S. 4246-4247
Piepgras, Johannes; Mueller, Aneka; Steffen, Falk et al.
Neurofilament light chain levels reflect outcome in a patient with glutamic acid decarboxylase 65 antibody-positive autoimmune encephalitis under immune checkpoint inhibitor therapyEUROPEAN JOURNAL OF NEUROLOGY. Bd. 28. H. 3. 2021 S. 1086-1089
Muhammad, Khalid; Xavier, Delicia; Klein-Hessling, Stefan et al.
NFAT5 Controls the Integrity of EpidermisFRONTIERS IN IMMUNOLOGY. Bd. 12. 2021
Koenig, Anika; Vaeth, Martin; Chiarolla, Cristina Maria et al.
NFATc1/alpha A and Blimp-1 support the follicular and effector phenotype of murine TregsEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 222-222
Uphaus, Timo; Steffen, Falk; Muthuraman, Muthuraman et al.
NfL predicts relapse-free progression in a longitudinal multiple sclerosis cohort studyEBIOMEDICINE. Bd. 72. 2021
Kavazovic, I.; Krapic, M.; Parga-Vidal, L. et al.
Obesity-induced memory CD8 T cell dysfunction in mice is independent of direct insulin signalingFEBS OPEN BIO. Bd. 11. 2021 S. 456-456
Rolfes, Leoni; Pawlitzki, Marc; Pfeuffer, Steffen et al.
Ocrelizumab Extended Interval Dosing in Multiple Sclerosis in Times of COVID-19NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION. Bd. 8. H. 5. 2021
Lacki, Mateusz K.; Startek, Michal P.; Brehmer, Sven et al.
OpenTIMS, TimsPy, and TimsR: Open and Easy Access to timsTOF Raw DataJOURNAL OF PROTEOME RESEARCH. Bd. 20. H. 4. 2021 S. 2122-2129
Lordick, Florian; Al-Batran, Salah-Eddin; Ganguli, Arijit et al.
Patient-reported outcomes from the phase II FAST trial of zolbetuximab plus EOX compared to EOX alone as first-line treatment of patients with metastatic CLDN18.2+gastroesophageal adenocarcinomaGASTRIC CANCER. Bd. 24. H. 3. 2021 S. 721-730
Appel, Dominik; Hummel, Regina; Weidemeier, Martin et al.
Pharmacologic Inhibition of ADAM10 Attenuates Brain Tissue Loss, Axonal Injury and Pro-inflammatory Gene Expression Following Traumatic Brain Injury in MiceFRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. Bd. 9. 2021
Diener, Nathalie; Fontaine, Jean -Fred; Klein, Matthias et al.
Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zonePROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 118. H. 38. 2021
Larochelle, Catherine; Wasser, Beatrice; Jamann, Helene et al.
Pro-inflammatory T helper 17 directly harms oligodendrocytes in neuroinflammationPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 118. H. 34. 2021
Haftmann, Claudia; Zwicky, Pascale; Ingelfinger, Florian et al.
Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of T-reg developmentSCIENCE IMMUNOLOGY. Bd. 6. H. 65. 2021
Tuereci, Oezlem; Sahin, Ugur
Racing for a SARS-CoV-2 vaccineEMBO MOLECULAR MEDICINE. Bd. 13. H. 11. 2021
Carriche, Guilhermina M.; Almeida, Luis; Stuve, Philipp et al.
Regulating T-cell differentiation through the polyamine spermidineJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Bd. 147. H. 1. 2021 S. 335-+
Tuzlak, Selma; Dejean, Anne S.; Iannacone, Matteo et al.
Repositioning T-H cell polarization from single cytokines to complex helpNATURE IMMUNOLOGY. Bd. 22. H. 10. 2021 S. 1210-1217
Lutz, Manfred B.; Backer, Ronald A.; Clausen, Bjoern E.
Revisiting Current Concepts on the Tolerogenicity of Steady-State Dendritic Cell Subsets and Their Maturation StagesJOURNAL OF IMMUNOLOGY. Bd. 206. H. 8. 2021 S. 1681-1689
Almeida, Luis; Dhillon-LaBrooy, Ayesha; Castro, Carla N. et al.
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein SynthesisIMMUNITY. Bd. 54. H. 1. 2021 S. 68-+
Seitz, Caspar B.; Steffen, Falk; Muthuraman, Muthuraman et al.
Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosisTHERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS. Bd. 14. 2021
Hummel, Regina; Lang, Manuel; Walderbach, Simona et al.
Single intracerebroventricular progranulin injection adversely affects the blood-brain barrier in experimental traumatic brain injuryJOURNAL OF NEUROCHEMISTRY. Bd. 158. H. 2. 2021 S. 342-357
Delacher, Michael; Simon, Malte; Sanderink, Lieke et al.
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cellsIMMUNITY. Bd. 54. H. 4. 2021 S. 702-+
Johann, Lisa; Waisman, Ari
Spotlight The astrocyte LAMP lights a T cell TRAIL of deathNEURON. Bd. 109. H. 9. 2021 S. 1423-1425
Griessl, Marion; Renzaho, Angelique; Freitag, Kirsten et al.
Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell "Memory Inflation" and Avoid Immune EvasionFRONTIERS IN IMMUNOLOGY. Bd. 12. 2021
Ostkamp, Patrick; Salmen, Anke; Pignolet, Beatrice et al.
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severityPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 118. H. 1. 2021
Bitar, Lynn; Schumann, Ulrike; Koenig, Renate et al.
Targeting Immune Modulators in Glioma While Avoiding Autoimmune ConditionsCANCERS. Bd. 13. H. 14. 2021
Haege, Sigrun; Buescher, Nicole; Pakulska, Victoria et al.
The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious VirusCELLS. Bd. 10. H. 11. 2021
Stergiou, Natascha; Urschbach, Moritz; Gabba, Adele et al.
The Development of Vaccines from Synthetic Tumor-Associated Mucin Glycopeptides and their Glycosylation-Dependent Immune ResponseCHEMICAL RECORD. Bd. 21. H. 11. 2021 S. 3313-3331