Forschungszentrum für Immuntherapie (FZI)
Forschungsschwerpunkt / Johannes Gutenberg-Universität Mainz
Krienke, Christina; Kolb, Laura; Diken, Elif et al.
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitisSCIENCE. Bd. 371. H. 6525. 2021 S. 146-+
Voss, Ralf-Holger; Birtel, Matthias; Theobald, Matthias et al.
A TCR-Like CAR Recruiting Endogenous CD3 Proves Efficacious Tumor Antigen Recognition via Retroviral, IVT-RNA or CRISPR/Cas9 Expression Systems in Human T-Cells and Perceives Costimulatory Signals in CisMOLECULAR THERAPY. Bd. 29. H. 4. 2021 S. 329-330
Wild, J.; Ringen, J.; Knopp, T. et al.
Acute induction of psoriasis-like skin inflammation disturbes vascular tone and provokes a rapid blood pressure response in miceEUROPEAN HEART JOURNAL. Bd. 42. 2021 S. 3353-3353
Ihbe, Natascha; Le Prieult, Florie; Wang, Qi et al.
Adaptive Mechanisms of Somatostatin-Positive Interneurons after Traumatic Brain Injury through a Switch of alpha Subunits in L-Type Voltage-Gated Calcium ChannelsCEREBRAL CORTEX. Bd. 32. H. 5. 2021 S. 1093-1109
Loers, Gabriele; Appel, Dominik; Lutz, David et al.
Amelioration of the abnormal phenotype of a new L1 syndrome mouse mutation with L1 mimeticsFASEB JOURNAL. Bd. 35. H. 2. 2021
Gasanov, Eugene V.; Jedrychowska, Justyna; Pastor, Michal et al.
An improved method for precise genome editing in zebrafish using CRISPR-Cas9 techniqueMOLECULAR BIOLOGY REPORTS. Bd. 48. H. 2. 2021 S. 1951-1957
Grigg, John B.; Shanmugavadivu, Arthi; Regen, Tommy et al.
Antigen presenting group 3 innate lymphoid cells orchestrate neuroinflammationJOURNAL OF IMMUNOLOGY. Bd. 206. 2021
Grigg, John B.; Shanmugavadivu, Arthi; Regen, Tommy et al.
Antigen-presenting innate lymphoid cells orchestrate neuroinflammationNATURE. Bd. 600. H. 7890. 2021 S. 707-+
Wendel, Philipp; Reindl, Lisa Marie; Bexte, Tobias et al.
Arming Immune Cells for Battle: A Brief Journey through the Advancements of T and NK Cell ImmunotherapyCANCERS. Bd. 13. H. 6. 2021
Schmaul, Samantha; Hanuscheck, Nicholas; Bittner, Stefan
Astrocytic potassium and calcium channels as integrators of the inflammatory and ischemic CNS microenvironmentBIOLOGICAL CHEMISTRY. Bd. 402. H. 12. 2021 S. 1519-1530
Xia, Ning; Hasselwander, Solveig; Reifenberg, Gisela et al.
B Lymphocyte-Deficiency in Mice Causes Vascular Dysfunction by Inducing NeutrophiliaBIOMEDICINES. Bd. 9. H. 11. 2021
Ozdemir, Zehra Narli; Seval, Guldane Cengiz; Sahin, Ugur et al.
Blastic Plasmacytoid Dendritic Cell Neoplasm: Single Center Experience on a Rare Hematological MalignancyINDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION. Bd. 37. H. 1. 2021 S. 67-75
Mai, Elias K.; Miah, Kaya; Bertsch, Uta et al.
Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of age (vol 35, pg 809, 2021)LEUKEMIA. Bd. 35. H. 12. 2021 S. 3636-3636
Muth, Sabine; Klaric, Annekatrin; Radsak, Markus et al.
CD27 expression on Treg cells limits immune responses against tumorsJOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 100. H. 3. 2021 S. 439-449
Almeida, Luis; Dhillon-LaBrooy, Ayesha; Carriche, Guilhermina et al.
CD4(+)& nbsp;T-cell differentiation and function: Unifying glycolysis, fatty acid oxidation, polyamines NAD mitochondriaJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Bd. 148. H. 1. 2021 S. 16-32
Jacobs, Benedikt; Gebel, Veronika; Heger, Lukas et al.
Characterization and Manipulation of the Crosstalk Between Dendritic and Natural Killer Cells Within the Tumor MicroenvironmentFRONTIERS IN IMMUNOLOGY. Bd. 12. 2021
Afzal, Muhammad; Sielaff, Malte; Curella, Valentina et al.
Characterization of 150 Wheat Cultivars by LC-MS-Based Label-Free Quantitative Proteomics Unravels Possibilities to Design Wheat Better for Baking Quality and Human HealthPLANTS-BASEL. Bd. 10. H. 3. 2021
Lindenberg, Marc; Almeida, Luis; Dhillon-LaBrooy, Ayesha et al.
Clarithromycin impairs tissue-resident memory and Th17 responses to macrolide-resistant Streptococcus pneumoniae infectionsJOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 99. H. 6. 2021 S. 817-829
Lindenberg, Marc; Almeida, Luis; Labrooy, Ayesha Dhillon et al.
Clarithromycin impairs tissue-resident memory and Th17 responses to macrolide-resistant Streptococcus pneumoniae infectionsEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 69-69
Bresadola, Luisa; Weber, David; Ritzel, Christoph et al.
Comprehensive Genomic and Transcriptomic Analysis of Three Synchronous Primary Tumours and a Recurrence from a Head and Neck Cancer PatientINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 22. H. 14. 2021
Reddehase, Matthias J.; Holtappels, Rafaela; Lemmermann, Niels A. W.
Consequence of Histoincompatibility beyond GvH-Reaction in Cytomegalovirus Disease Associated with Allogeneic Hematopoietic Cell Transplantation: Change of ParadigmVIRUSES-BASEL. Bd. 13. H. 8. 2021
Dermicik, Filiz; Kostka, Susanna Lopez; Tenzer, Stefan et al.
Cross-reactive, natural IgG recognizing L. major promote parasite internalization by dendritic cells and promote protective immunityJOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 100. H. 3. 2021 S. 451-460
Demircik, Filiz; Kostka, Susanna Lopez; Tenzer, Stefan et al.
Cross-reactive, natural IgG recognizing L. major promote parasite internalization by dendritic cells and promote protective immunity (Oct, 10.1007/s00109-021-02137-4, 2021)JOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 100. H. 3. 2021 S. 461-461
Olmedo, Addi Josua Romero; Schulz, Axel R.; Huber, Magdalena et al.
Deep phenotypical characterization of human CD3+CD56+T cells by mass cytometryEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 273-273
Rosigkeit, Sebastian; Kruchem, Marie; Thies, Dorothe et al.
Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancerINTERNATIONAL JOURNAL OF CANCER. Bd. 149. H. 9. 2021 S. 1670-1682
Legscha, Kevin Jan; Ferreira, Edite Antunes; Chamoun, Antonios et al.
Delta 133p53 alpha enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumor immunityJOURNAL FOR IMMUNOTHERAPY OF CANCER. Bd. 9. H. 6. 2021
Ose, Robert; Weigmann, Benno; Schuppan, Detlef et al.
Depletion of CD56(+)CD3(+) invariant natural killer T cells prevents allergen-induced inflammation in humanized miceJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Bd. 148. H. 4. 2021 S. 1081-+
Karl, M.; Hasselwander, S.; Reifenberg, G. et al.
Differential effects of B cell knockout and antibody deficiency in murine models of diet-induced non-alcoholic fatty liver diseaseNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 394. H. SUPPL 1. 2021 S. S13-S14
Liebmann, Marie; Korn, Lisanne; Janoschka, Claudia et al.
Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunityBRAIN. Bd. 144. 2021 S. 3126-3141
Lemmermann, Niels A. W.; Reddehase, Matthias J.
Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus InfectionPATHOGENS. Bd. 10. H. 6. 2021
Woods, Kevin; Guezguez, Borhane
Dynamic Changes of the Bone Marrow Niche: Mesenchymal Stromal Cells and Their Progeny During Aging and LeukemiaFRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. Bd. 9. 2021
Ritter, Katharina; Jung, Kirsten; Dolderer, Christopher et al.
Early Reciprocal Effects in a Murine Model of Traumatic Brain Injury and Femoral FractureMEDIATORS OF INFLAMMATION. Bd. 2021. 2021
Alberg, Irina; Kramer, Stefan; Leps, Christian et al.
Effect of Core-Crosslinking on Protein Corona Formation on Polymeric MicellesMACROMOLECULAR BIOSCIENCE. Bd. 21. H. 4. 2021
Ziebart, Alexander; Breit, Christian; Ruemmler, Robert et al.
Effect of fluid resuscitation on cerebral integrity A prospective randomised porcine study of haemorrhagic shockEUROPEAN JOURNAL OF ANAESTHESIOLOGY. Bd. 38. H. 4. 2021 S. 411-421
Landa, Jon; Guasp, Mar; Miguez-Cabello, Federico et al.
Encephalitis with Autoantibodies against the Glutamate Kainate Receptors GluK2ANNALS OF NEUROLOGY. Bd. 90. H. 1. 2021 S. 101-117
Buehring, Sri; Yemelin, Alexander; Michna, Thomas et al.
Evidence of a New MoYpd1p Phosphotransferase Isoform in the Multistep Phosphorelay System of Magnaporthe oryzaeJOURNAL OF FUNGI. Bd. 7. H. 5. 2021
Joisten, Niklas; Rademacher, Annette; Warnke, Clemens et al.
Exercise Diminishes Plasma Neurofilament Light Chain and Reroutes the Kynurenine Pathway in Multiple SclerosisNEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION. Bd. 8. H. 3. 2021
Jung, Sascha; Fuchs, Natalie; Johe, Patrick et al.
Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo StudiesJOURNAL OF MEDICINAL CHEMISTRY. Bd. 64. H. 16. 2021 S. 12322-12358
Ohl, Kim; Subramanyam, Sudheendra Hebbar; Look, Thomas et al.
Foxp3-specific deletion of CREB generates Th2 biased ST-2 positive regulatory T-cells with enhanced IL-10 production and suppressive capacityEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 60-60
Treimer, Ernestine; Niedermayer, Kathrin; Schumann, Sven et al.
Galloway-Mowat syndrome: New insights from bioinformatics and expression during Xenopus embryogenesisGENE EXPRESSION PATTERNS. Bd. 42. 2021
Price, Leah S.; Adamow, Matthew; Attig, Sebastian et al.
Gating Harmonization Guidelines for Intracellular Cytokine Staining Validated in Second International Multiconsortia Proficiency Panel Conducted by Cancer Immunotherapy Consortium (CIC/CRI)CYTOMETRY PART A. Bd. 99. H. 1. 2021 S. 107-116
Cipriani, Barbara; Naylor, Alan; Milne, Gavin et al.
GPR65 is a critical mediator of low pH induced immunosuppressive signalling in tumor associated macrophages: Human target validation of GPR65 as a novel innate immune checkpoint and discovery of potent, selective GPR65 antagonists.CANCER RESEARCH. Bd. 81. H. 13. 2021
Cossarizza, Andrea; Chang, Hyun-Dong; Radbruch, Andreas et al.
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. H. 12. 2021 S. 2708-3145
Schneider-Hohendorf, Tilman; Schulte-Mecklenbeck, Andreas; Ostkamp, Patrick et al.
High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patientsMULTIPLE SCLEROSIS JOURNAL. Bd. 27. H. 10. 2021 S. 1491-1496
Kaare, Maria; Mikheim, Kaie; Lillevali, Kersti et al.
High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient MiceBIOMEDICINES. Bd. 9. H. 9. 2021
Mikulicic, Snjezana; Strunk, Johannes; Florin, Luise
HPV16 Entry into Epithelial Cells: Running a GauntletVIRUSES-BASEL. Bd. 13. H. 12. 2021
Sielaff, Malte; Curella, Valentina; Neerukonda, Manjusha et al.
Hybrid QconCAT-Based Targeted Absolute and Data-Independent Acquisition-Based Label-Free Quantification Enables In-Depth Proteomic Characterization of Wheat Amylase/Trypsin Inhibitor ExtractsJOURNAL OF PROTEOME RESEARCH. Bd. 20. H. 3. 2021 S. 1544-1557
Regen, Tommy; Isaac, Sandrine; Amorim, Ana et al.
IL-17 controls central nervous system autoimmunity through the intestinal microbiomeSCIENCE IMMUNOLOGY. Bd. 6. H. 56. 2021
Moos, S.; Mohebiany, A. N.; Waisman, A. et al.
Imiquimod-induced psoriasis-like dermatitis in mice depends on IL-17 signaling of keratinocytesEXPERIMENTAL DERMATOLOGY. Bd. 30. H. 3. 2021 S. E20-E20
Freitag, Kirsten; Hamdan, Sara; Reddehase, Matthias J. et al.
Immunodominant Cytomegalovirus Epitopes Suppress Subdominant Epitopes in the Generation of High-Avidity CD8 T CellsPATHOGENS. Bd. 10. H. 8. 2021