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Dual roles of B lymphocytes in mouse models of diet-induced nonalcoholic fatty liver diseaseHEPATOLOGY. 2022
Czysch, Christian; Medina-Montano, Carolina; Dal, Nils-Jorgen Knudsen et al.
End Group Dye-Labeled Polycarbonate Block Copolymers for Micellar (Immuno-)Drug DeliveryMACROMOLECULAR RAPID COMMUNICATIONS. 2022
Schmitt, Sascha; Huppertsberg, Anne; Klefenz, Adrian et al.
Fluorescence Correlation Spectroscopy Monitors the Fate of Degradable Nanocarriers in the Blood StreamBIOMACROMOLECULES. 2022
Schuppan, Detlef; Myneni, Sudharani; Surabattula, Rambabu
Liquid biomarkers for fibrotic NASH - progress in a complex fieldJOURNAL OF HEPATOLOGY. Bd. 76. H. 1. 2022 S. 5-7
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pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophagesPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 119. H. 12. 2022
Schuppan, D
: Can Plant Materials Be Valuable in the Treatment of Periodontal Diseases?Pharmaceutics. Bd. 13. 2021 S. 2185
Crouchet, Emilie; Bandiera, Simonetta; Fujiwara, Naoto et al.
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discoveryNATURE COMMUNICATIONS. Bd. 12. H. 1. 2021
Villesen, Ida; Langholm, Lasse; Leeming, Diana et al.
A novel liver-specific fibrosis biomarker, PRO-C18L, can predict response to antifibrotic treatment, with a peroxisome proliferator activated receptor -y agonist, in patients with chronic hepatitis CJOURNAL OF HEPATOLOGY. Bd. 75. 2021 S. S633-S633
Schuppan, Detlef; Maki, Markku; Lundin, Knut E. A. et al.
A randomized trial of a transglutaminase 2 inhibitor for celiac diseaseNEW ENGLAND JOURNAL OF MEDICINE. Bd. 385. H. 1. 2021 S. 35-45
Schuppan, D
A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosisJ Hepatology. 2021 S. 816
Schuppan, Detlef; Maki, Markku; Lundin, Knut E. A.
A Trial of a Transglutaminase 2 Inhibitor in Celiac Disease. ReplyNEW ENGLAND JOURNAL OF MEDICINE. Bd. 385. H. 16. 2021
Freise, Christian; Lee, Hyunho; Chronowski, Christopher et al.
Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cellsPLOS ONE. Bd. 16. H. 9. 2021
Afzal, Muhammad; Sielaff, Malte; Curella, Valentina et al.
Characterization of 150 Wheat Cultivars by LC-MS-Based Label-Free Quantitative Proteomics Unravels Possibilities to Design Wheat Better for Baking Quality and Human HealthPLANTS-BASEL. Bd. 10. H. 3. 2021
Verdu, Elena F.; Schuppan, Detlef
Co-factors, Microbes, and Immunogenetics in Celiac Disease to Guide Novel Approaches for Diagnosis and TreatmentGASTROENTEROLOGY. Bd. 161. H. 5. 2021 S. 1395-+
Rosigkeit, Sebastian; Kruchem, Marie; Thies, Dorothe et al.
Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancerINTERNATIONAL JOURNAL OF CANCER. Bd. 149. H. 9. 2021 S. 1670-1682
Ose, Robert; Weigmann, Benno; Schuppan, Detlef et al.
Depletion of CD56(+)CD3(+) invariant natural killer T cells prevents allergen-induced inflammation in humanized miceJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Bd. 148. H. 4. 2021 S. 1081-+
Fleck, Ann-Katrin; Hucke, Stephanie; Teipel, Flavio et al.
Dietary conjugated linoleic acid links reduced intestinal inflammateon to amelioration of CNS autoimmunityBRAIN. Bd. 144. 2021 S. 1152-1166
Karl, M.; Hasselwander, S.; Reifenberg, G. et al.
Differential effects of B cell knockout and antibody deficiency in murine models of diet-induced non-alcoholic fatty liver diseaseNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 394. H. SUPPL 1. 2021 S. S13-S14
Vollmar, Johanna; Kim, Yong Ook; Marquardt, Jens Uwe et al.
Functional inhibition of Oct leads to HNF4 alpha upregulationEXPERIMENTAL AND THERAPEUTIC MEDICINE. Bd. 21. H. 4. 2021
El Hassouni, Khaoula; Sielaff, Malte; Curella, Valentina et al.
Genetic architecture underlying the expression of eight alpha-amylase trypsin inhibitorsTHEORETICAL AND APPLIED GENETICS. Bd. 134. H. 10. 2021 S. 3427-3441
Pinto-Sanchez, Maria Ines; Nardelli, Andrea; Borojevic, Rajka et al.
Gluten-Free Diet Reduces Symptoms, Particularly Diarrhea, in Patients With Irritable Bowel Syndrome and Antigliadin IgGCLINICAL GASTROENTEROLOGY AND HEPATOLOGY. Bd. 19. H. 11. 2021 S. 2343-+
Sielaff, Malte; Curella, Valentina; Neerukonda, Manjusha et al.
Hybrid QconCAT-Based Targeted Absolute and Data-Independent Acquisition-Based Label-Free Quantification Enables In-Depth Proteomic Characterization of Wheat Amylase/Trypsin Inhibitor ExtractsJOURNAL OF PROTEOME RESEARCH. Bd. 20. H. 3. 2021 S. 1544-1557
Dornas, Waleska; Schuppan, Detlef
Measurement of Reactive Oxygen and Nitrogen Species in Living Cells Using the Probe 2 ',7 '-DichlorodihydrofluoresceinBIO-PROTOCOL. Bd. 11. H. 24. 2021
Schaller, Eva; Ma, Andi; Gosch, Lisa Chiara et al.
New 3-Aryl-2-(2-thienyl)acrylonitriles with High Activity Against Hepatoma CellsINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 22. H. 5. 2021
Stoelzel, Ulrich; Schuppan, Detlef
New therapeutic option for acute hepatic porphyriasDEUTSCHE MEDIZINISCHE WOCHENSCHRIFT. Bd. 146. H. 15. 2021 S. 955-958
Stoelzel, Ulrich; Schuppan, Detlef
New Therapy Option for acute hepatic Porphyrias ReplyDEUTSCHE MEDIZINISCHE WOCHENSCHRIFT. Bd. 146. H. 23. 2021 S. 1578-1579
Ose, Robert; Weigmann, Benno; Sudowe, Stephan et al.
Oral administration of short chain fatty acids to PBMC-engrafted humanized mice prevents allergen-dependent airway and intestinal inflammationEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 78-78
Karsdal, Morten Asser; Kraus, Virginia Byers; Shevell, Diane et al.
Profiling and targeting connective tissue remodeling in autoimmunity - A novel paradigm for diagnosing and treating chronic diseasesAUTOIMMUNITY REVIEWS. Bd. 20. H. 1. 2021
Fouad, Yasser; Palmer, Melissa; Chen, Minjun et al.
Redefinition of Fatty Liver Disease from NAFLD to MAFLD through the Lens of Drug Development and Regulatory ScienceJOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY. Bd. 10. H. 2. 2021 S. 374-382
Schuppan, D; Friesing-Sosnik, T
So erkennen Sie entzündliche Weizensensitivitäten : Zöliakie, Reizdarm und andere chronische ErkrankungenMMW Fortschritte Medizin. 2021 S. 47-52
Huppertsberg, Anne; Kaps, Leonard; Zhong, Zifu et al.
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune ModulatorsJOURNAL OF THE AMERICAN CHEMICAL SOCIETY. Bd. 143. H. 26. 2021 S. 9872-9883
Scherf, Katharina Anne; Catassi, Carlo; Chirdo, Fernando G. et al.
Statement of the Prolamin Working Group on the Determination of Gluten in Fermented Foods Containing Partially Hydrolyzed GlutenFRONTIERS IN NUTRITION. Bd. 7. 2021
Matzner, Johannes; Pickert, Geethanjali; Fittler, Nicola J. et al.
STRUCTURALLY ENGINEERED FATTY ACID SEFA-1024 ALLEVIATES COLITIS IN MICE BY RESTORING INTESTINAL MUCOSAL BARRIER FUNCTIONGASTROENTEROLOGY. Bd. 160. H. 6. 2021 S. S617-S617
Ventura, Manuel A. Encalada; Hils, Martin; Tewes, Bernhard et al.
THE ORAL TISSUE TRANSGLUTAMINASE INHIBITOR ZED1227 PREVENTS GLUTEN-INDUCED ENTEROPATHY IN A TRANSGENIC MOUSE MODEL OF CELIAC DISEASEGASTROENTEROLOGY. Bd. 160. H. 6. 2021 S. S53-S54
Cerf-Bensussan, Nadine; Schuppan, Detlef
The Promise of Novel Therapies to Abolish Gluten Immunogenicity in Celiac DiseaseGASTROENTEROLOGY. Bd. 161. H. 1. 2021 S. 21-24
Wagner, Willi L.; Foehst, Sonja; Hock, Jessica et al.
3D analysis of microvasculature in murine liver fibrosis models using synchrotron radiation-based microtomographyANGIOGENESIS. 2020
Bockamp, Ernesto
A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression.PLoS One. 2020 S. 10
Matzner, Johannes; Pickert, Geethanjali; Thies, Dorothe et al.
A GUT-TARGETED EICOSAPENTAENOIC ACID DERIVATIVE, SEFA-1024, AMELIORATES DEXTRAN SODIUM SULFATE (DSS)-INDUCED INTESTINAL INFLAMMATIONGASTROENTEROLOGY. Bd. 158. H. 6. 2020 S. S505-S505
Schuppan, D
A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis.J Hepatol. Bd. 10.1016/j.jhep.2019.11.024. 2020 S. 19
Yurugi, Hajime; Zhuang, Yinyin; Siddiqui, Farid et al.
A subset of flavaglines inhibits KRAS nanoclustering and activationJOURNAL OF CELL SCIENCE. Bd. 133. H. 12. 2020
Abe, Hiroyuki; Schuppan, Detlef
beta-arrestin: Dr Jekyll and Mr Hyde in NASH and fibrosisJOURNAL OF HEPATOLOGY. Bd. 72. H. 5. 2020 S. 813-815
Ziegler, Kira; Kunert, Anna T.; Reinmuth-Selzle, Kathrin et al.
Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-kappa B: Implications for the health effects of air pollution and oxidative stressREDOX BIOLOGY. Bd. 37. 2020
Ebert, Antonia; Koenig, Jochem; Frommer, Lara et al.
Chromogranin Serves as Novel Biomarker of Endocrine and Gastric AutoimmunityJOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. Bd. 105. H. 8. 2020 S. 2606-2615
Karsdal, Morten A.; Daniels, Samuel J.; Nielsen, Signe Holm et al.
Collagen biology and non-invasive biomarkers of liver fibrosisLIVER INTERNATIONAL. Bd. 40. H. 4. 2020 S. 736-750
Wei, Guoxian; Darwish, Ghassan; Oppenheim, Frank G. et al.
Commensal Bacterium Rothia aeria Degrades and Detoxifies Gluten via a Highly Effective Subtilisin EnzymeNUTRIENTS. Bd. 12. H. 12. 2020
Wei, Guangyan; An, Ping; Vaid, Kahini A. et al.
Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancerAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. Bd. 318. H. 1. 2020 S. G174-G188
Schuppan, Detlef
Endothelial GLP-1 (Glucagon-LikeArterioscler Thromb Vasc Biol. 2020 S. 13
Helmstaedter, Johanna; Frenis, Katie; Filippou, Konstantina et al.
Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial HypertensionARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. Bd. 40. H. 1. 2020 S. 145-158
Leeming, Diana Julie; Nielsen, Signe Holm; Vongsuvanh, Roslyn et al.
Endotrophin, a pro-peptide of Type VI collagen, is a biomarker of survival in cirrhotic patients with hepatocellular carcinomaHEPATIC ONCOLOGY. 2020
Fritscher-Ravens, Annette; Ruchay, Zino; Pflaum, Theresa et al.
EXCLUSION OF ATYPICAL FOOD ALLERGENS DETECTED BY CONFOCAL ENDOMICROSCOPY IS SUPERIOR TO A LOW FODMAP DIET IN PATIENTS WITH FOOD-SENSITIVE IBSGASTROENTEROLOGY. Bd. 158. H. 6. 2020 S. S135-S135