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Publikationen
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Rodriguez-Alvarez, Marta; Kim, Daria; Khobta, Andriy

EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions

BIOMOLECULES. Bd. 10. H. 6. 2020


Taubmann, Andreas; Willershausen, Ines; Walter, Christian et al.

Genotoxic and cytotoxic potential of methacrylate-based orthodontic adhesives

CLINICAL ORAL INVESTIGATIONS. 2020



Kiweler, Nicole; Wuensch, Desiree; Wirth, Matthias et al.

Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. Bd. 146. H. 2. 2020 S. 343-356


Friedrich, Annabelle; Assmann, Ann-Sophie; Schumacher, Lena et al.

In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi)

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 21. H. 13. 2020


Seiwert, Nina; Heylmann, Daniel; Hasselwander, Solveig et al.

Mechanism of colorectal carcinogenesis triggered by heme iron from red meat

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. Bd. 1873. H. 1. 2020



Bergholz, Liana M.; Grimminger, Peter; Dikeoulia, Elsa et al.

Pilot Study on Malnutrition and DNA Damage in Patients with Newly Diagnosed Gastrointestinal Tumors: Is DNA Damage Reversible by Early Individualized Nutritional Support?

JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES. Bd. 29. H. 4. 2020 S. 569-577


Matos-Rodrigues, Gabriel E.; Tan, Pedro B.; Rocha-Martins, Mauricio et al.

Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome

DISEASE MODELS & MECHANISMS. Bd. 13. H. 10. 2020


Gomes, Anielle L.; Matos-Rodrigues, Gabriel E.; Frappart, Pierre-Olivier et al.

RINT1 Loss Impairs Retinogenesis Through TRP53-Mediated Apoptosis

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. Bd. 8. 2020


Lankes, Katharina; Hassan, Zonera; Doffo, Maria Josefina et al.

Targeting the ubiquitin-proteasome system in a pancreatic cancer subtype with hyperactive MYC

MOLECULAR ONCOLOGY. Bd. 14. H. 12. 2020 S. 3048-3064


Dzulko, Melanie; Pons, Miriam; Henke, Andreas et al.

The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. Bd. 1874. H. 2. 2020


Volcic, Meta; Sparrer, Konstantin M. J.; Koepke, Lennart et al.

Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1

NATURE MICROBIOLOGY. Bd. 5. H. 10. 2020 S. 1247-+


He, Yang; Kaina, Bernd

Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide?

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 20. H. 7. 2019


Liebl, Magdalena C.; Hofmann, Thomas G.

Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road

BIOESSAYS. Bd. 41. H. 12. 2019


Wenz, Christine; Faust, Dagmar; Linz, Berenike et al.

Cell-cell contacts protect against t-BuOOH-induced cellular damage and ferroptosis in vitro

ARCHIVES OF TOXICOLOGY. Bd. 93. H. 5. 2019 S. 1265-1279


Ponath, Viviane; Heylmann, Daniel; Haak, Tobias et al.

Compromised DNA Repair and Signalling in Human Granulocytes

JOURNAL OF INNATE IMMUNITY. Bd. 11. H. 1. 2019 S. 74-85


Mahn, Friederike L.; Castven, Darko; Pereira, Sharon P. et al.

DECIPHERING THE ROLE OF PARP-1 AS A THERAPEUTIC TARGET IN KRAS-MUTATED INTRAHEPATIC CHOLANGIOCARCINOMA

HEPATOLOGY. Bd. 70. 2019 S. 1143A-1143A


Kaina, Bernd; Christmann, Markus

DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas

DNA REPAIR. Bd. 78. 2019 S. 128-141



Heinz, Kathrin S.; Rapp, Alexander; Casas-Delucchi, Corella S. et al.

DNA replication dynamics of vole genome and its epigenetic regulation

EPIGENETICS & CHROMATIN. Bd. 12. 2019


Gogiraju, Rajinikanth; Hubert, Astrid; Fahrer, Joerg et al.

Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling

CIRCULATION-HEART FAILURE. Bd. 12. H. 1. 2019


Christmann, Markus; Kaina, Bernd

Epigenetic regulation of DNA repair genes and implications for tumor therapy

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. Bd. 780. 2019 S. 15-28


Rund, Katharina M.; Heylmann, Daniel; Seiwert, Nina et al.

Formation of trans-epoxy fatty acids correlates with formation of isoprostanes and could serve as biomarker of oxidative stress

PROSTAGLANDINS & OTHER LIPID MEDIATORS. Bd. 144. 2019


Tomicic, Maja T.; Steigerwald, Christian; Rasenberger, Birgit et al.

Functional mismatch repair and inactive p53 drive sensitization of colorectal cancer cells to irinotecan via the IAP antagonist BV6

ARCHIVES OF TOXICOLOGY. Bd. 93. H. 8. 2019 S. 2265-2277


Beyer, Mandy; Romanski, Annette; Mustafa, Al-Hassan M. et al.

HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of beta-catenin, MYC, and WT1

CANCERS. Bd. 11. H. 10. 2019


Pons, Miriam; Nagel, Georg; Zeyn, Yanira et al.

Human Platelet Lysate as Validated Replacement for Animal Serum to Assess Chemosensitivity

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION. Bd. 36. H. 2. 2019 S. 277-288



Liebl, M. C.; Hofmann, T. G.

Identification of responders to immune checkpoint therapy: which biomarkers have the highest value?

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. Bd. 33. 2019 S. 52-56


Kraus, Alexander; McKeague, Maureen; Seiwert, Nina et al.

Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O-6-methylguanine in vivo

ARCHIVES OF TOXICOLOGY. Bd. 93. H. 2. 2019 S. 559-572


Neitzel, Carina; Seiwert, Nina; Goeder, Anja et al.

Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation

CELLS. Bd. 8. H. 8. 2019


Kitsera, Nataliya; Rodriguez-Alvarez, Marta; Emmert, Steffen et al.

Nucleotide excision repair of abasic DNA lesions

NUCLEIC ACIDS RESEARCH. Bd. 47. H. 16. 2019 S. 8537-8547


Guo, Haihong; Treude, Fabian; Kraemer, Oliver H. et al.

PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1

SCIENTIFIC REPORTS. Bd. 9. 2019


Tomicic, M.; Steigerwald, C.; Rasenberger, B. et al.

Survivin inhibitor LLP3 sensitizes colorectal cancer cells to irinotecan in the context of a specific XAF1/p53 signature

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 392. 2019 S. S9-S9



Aasland, Dorthe; Goetzinger, Laura; Hauck, Laura et al.

Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR-CHK1, p21, and NF-kappa B

CANCER RESEARCH. Bd. 79. H. 1. 2019 S. 99-113


He, Yang; Roos, Wynand P.; Wu, Qianchao et al.

The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death

MOLECULAR CANCER RESEARCH. Bd. 17. H. 5. 2019 S. 1129-1141


Laarmann, Kathrin; Kress, Joana M.; Kaina, Bernd et al.

Werner syndrome (WRN) DNA helicase and base excision repair (BER) factors maintain endothelial homeostasis

DNA REPAIR. Bd. 73. 2019 S. 17-27


Zaini, Mohamad A.; Mueller, Christine; de Jong, Tristan V. et al.

A p300 and SIRT1 Regulated Acetylation Switch of C/EBP alpha Controls Mitochondrial Function

CELL REPORTS. Bd. 22. H. 2. 2018 S. 497-511


Neitzel, C.; Stroh, S.; Nagel, G. et al.

A promising building block in the chemotherapy of colorectal cancer: The first-in-class mitochondrial disruptor CPI-613

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 391. 2018 S. S58-S58


Seiwert, N.; Neitzel, C.; Stroh, S. et al.

AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 391. 2018 S. S51-S51



Leonhardt, Michel; Sellmer, Andreas; Kraemer, Oliver H. et al.

Design and biological evaluation of tetrahydro-beta-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. Bd. 152. 2018 S. 329-357


Rund, Katharina M.; Ostermann, Annika I.; Kutzner, Laura et al.

Development of an LC-ESI(-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3-and n6-PUFAs

ANALYTICA CHIMICA ACTA. Bd. 1037. 2018 S. 63-74


Stojanovic, Nikolina; Dekanic, Ana; Paradzik, Mladen et al.

Differential Effects of Integrin alpha v Knockdown and Cilengitide on Sensitization of Triple-Negative Breast Cancer and Melanoma Cells to Microtubule Poisons

MOLECULAR PHARMACOLOGY. Bd. 94. H. 6. 2018 S. 1334-1351


Herrtwich, Laura; Nanda, Indrajit; Evangelou, Konstantinos et al.

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas (vol 167, pg 1264, 2016)

CELL. Bd. 174. H. 5. 2018 S. 1325-1326


Gock, Michael; Mullins, Christina S.; Harnack, Christine et al.

Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line

WORLD JOURNAL OF GASTROENTEROLOGY. Bd. 24. H. 33. 2018 S. 3749-3759


Gock, Michael; Mullins, Christina S.; Bergner, Carina et al.

Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines

WORLD JOURNAL OF GASTROENTEROLOGY. Bd. 24. H. 43. 2018 S. 4880-4892


Goeder, Anja; Emmerich, Claudia; Nikolova, Teodora et al.

HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130

NATURE COMMUNICATIONS. Bd. 9. 2018


Beyer, M; Kiweler, N; Mahboobi, S et al.

How to Distinguish Between the Activity of HDAC1-3 and HDAC6 with Western Blot

Oliver H. Krämer (Hrsg). HDAC/HAT Function Assessment and Inhibitor Development: Methods and protocols, Methods in Molecular Biology. Springer Science + Business Media, New York 2018