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Analysis of antibody patterns against retinal antigens in sera of patients with age-related macular degeneration

Laufzeit: 01.01.2005 - 31.12.2006

Kurzfassung


The aim of this study is to compare the antibody patterns against retinal antigens in sera of patients with age-related macular degeneration (AMD) and healthy subjects to learn more about possible immunological aspects of this disease and to identify some of the most important antigens.
The sera will be tested against Western blots of bovine retinal antigens. The IgG antibody patterns will then be analyzed by multivariate statistical techniques and some antigens will be identified via...
The aim of this study is to compare the antibody patterns against retinal antigens in sera of patients with age-related macular degeneration (AMD) and healthy subjects to learn more about possible immunological aspects of this disease and to identify some of the most important antigens.
The sera will be tested against Western blots of bovine retinal antigens. The IgG antibody patterns will then be analyzed by multivariate statistical techniques and some antigens will be identified via LC-MS/MS.
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