Univ.-Prof. Dr. rer. nat. Matthias Johannes Reddehase
FB 04 - Universitätsmedizin, Johannes Gutenberg-Universität Mainz
- 06131/39-33651 (Sekr. 33650)
- 06131/39-35604
Holtappels, Rafaela; Thomas, Doris; Podlech, Jürgen et al.
PATHOGENESIS AND IMMUNITY - The Putative Natural Killer Decoy Early Gene m04 (gp34) of Murine Cytomegalovirus Encodes an Antigenic Peptide Recognized by Protective Antiviral CD8 T CellsJournal of virology. a publication of the American Society for Microbiology. Bd. 74. H. 4. Washington, DC: ASM 2000 S. 1871 - 1884
Kurz, Sabine K.; Rapp, Maria; Steffens, Hans-Peter et al.
REPLICATION - Focal Transcriptional Activity of Murine Cytomegalovirus during Latency in the LungsJournal of virology. a publication of the American Society for Microbiology. Bd. 73. H. 1. Washington, DC: ASM 1999 S. 482 - 494
Grzimek, Natascha K.A.; Podlech, Jürgen; Steffens, Hans-Peter et al.
REPLICATION - In Vivo Replication of Recombinant Murine Cytomegalovirus Driven by the Paralogous Major Immediate-Early Promoter-Enhancer of Human CytomegalovirusJournal of virology. a publication of the American Society for Microbiology. Bd. 73. H. 6. Washington, DC: ASM 1999 S. 5043 - 5055
Kurz, Sabine K.; Reddehase, Matthias J.
REPLICATION - Patchwork Pattern of Transcriptional Reactivation in the Lungs Indicates Sequential Checkpoints in the Transition from Murine Cytomegalovirus Latency to RecurrenceJournal of virology. a publication of the American Society for Microbiology. Bd. 73. H. 10. Washington, DC: ASM 1999 S. 8612 - 8622
Steffens, H.-P.; Podlech, Jürgen; Kurz, Sabine et al.
Cytomegalovirus inhibits the engraftment of donor bone marrow cells by downregulation of hemopoietin gene expression in recipient stromaJournal of virology. Bd. 72. H. 6. Washington: American Society for Microbiology 1998 S. 5006 - 5015
Podlech, Jürgen; Steffens, H.-P.; Holtappels, Rafaela et al.
Cytomegalovirus pathogenesis after experimental bone marrow transplantationScholz, Martin (Hrsg). CMV-related immunopathology : 1st International Consensus Round Table Meeting, Frankfurt, August 1997 ; expert reviews on current and future anti-CMV treatment strategies. Basel: Karger 1998 S. 119 - 128
Dobonici, M.; Podlech, J.; Steffens, H.-P. et al.
Evidence against a key role for transforming growth factor-b1 in cytomegalovirus-induced bone marrow aplasiaThe journal of general virology. JGV. Bd. 79. H. 4. Reading: Society for General Microbiology 1998 S. 867 - 876
Steffens, H. P.; Kurz, Sabine; Holtappels, Rafaela et al.
Preemptive cd8 t-cell immunotherapy of acute cytomegalovirus infection prevents lethal disease, limits the burden of latent viral genomes, and reduces the risk of virus recurrenceJournal of virology. Bd. 72. H. 3. Washington: American Society for Microbiology 1998 S. 1797 - 1804
Podlech, Jürgen; Holtappels, Rafaela; Wirtz, N. et al.
Reconstitution of cd8 t cells is essential for the prevention of multiple-organ cytomegalovirus histopathology after bone marrow transplantationJournal of general virology. Bd. 79. Reading: Society for General Microbiology 1998 S. 2099 - 2104
Goss, Mariagabriela Alterio de; Holtappels, Rafaela; Steffens, Hans-Peter et al.
VIRAL PATHOGENESIS AND IMMUNITY - Control of Cytomegalovirus in Bone Marrow Transplantation Chimeras Lacking the Prevailing Antigen-Presenting Molecule in Recipient Tissues Rests Primarily on Recipient-Derived CD8 T CellsJournal of virology. a publication of the American Society for Microbiology. Bd. 72. H. 10. Washington, DC: ASM 1998 S. 7733 - 7744
Holtappels, Rafaela; Podlech, Jürgen; Geginat, Gernot et al.
VIRAL PATHOGENESIS AND IMMUNITY - Control of Murine Cytomegalovirus in the Lungs: Relative but Not Absolute Immunodominance of the Immediate-Early 1 Nonapeptide during the Antiviral Cytolytic T-Lymphocyte Response in Pulmonary InfiltratesJournal of virology. a publication of the American Society for Microbiology. Bd. 72. H. 9. Washington, DC: ASM 1998 S. 7201 - 7212
Mayer, A.; Podlech, Jürgen; Kurz, Sabine et al.
Bone marrow failure by cytomegalovirus is associated with an in vivo deficiency in the expression of essential stromal hemopoietin genesJournal of virology. Bd. 71. H. 6. Washington: American Society for Microbiology 1997 S. 4589 - 4598
Kurz, Sabine; Steffens, Hans-Peter; Mayer, Anna et al.
Latency versus Persistence or Intermittent Recurrences: Evidence for a Latent State of Murine Cytomegalovirus in the LungsJournal of virology. a publication of the American Society for Microbiology. Bd. 71. H. 4. Washington, DC: ASM 1997 S. 2980 - 2987
Reddehase, Matthias J.; Balthesen, Monika; Rapp, Maria et al.
The conditions of promary infection define the load of latent viral genome in organs and the risk of recurrent cytomegalovirus deseaseThe journal of experimental medicine. JEM. Bd. 179. H. 1. New York, NY: Rockefeller Univ. Press 1994 S. 185 - 194
Balthesen, M.; Dreher, L.; Lucin, P. et al.
The establishment of cytomegalovirus latency in organs is not linked to local virus production during primary infectionJournal of general virology. Bd. 75. Reading: Society for General Microbiology 1994 S. 2329 - 2336
Balthesen, M.; Messerle, M.; Reddehase, Matthias J.
Lungs are a major organ site of cytomegalovirus latency and recurrenceJournal of virology. Bd. 67. H. 9. Washington: American Society for Microbiology 1993 S. 5360 - 5366
Reddehase, Matthias Johannes; Reddehase, M. J.; Dreher - Stumpp, L. et al.
Hematopoietic stem cell deficiency resulting from cytomegalovirus infection of bone marrow stroma.Ann-Hematol. Bd. Ann-Hematol. 1992 S. A125-127
Reddehase, Matthias Johannes; Reddehase, M. J.
Bone marrow dysfunction in irradiated, cytomegalovirus-infected miceTransplant-Proc. Bd. Transplant-Proc. 1991 S. 10-11
Reddehase, Matthias Johannes; Reddehase, M. J.; Koszinowski, U. H.
Redistribution of critical major histocompatibility complex and T cell receptor-binding functions of residues in an antigenic sequence after biterminal substitutionEurop J Immunol. Bd. Europ J Immunol. 1991 S. 1697-1701
Reddehase, Matthias Johannes; Reddehase, M. J.; Busch, F. W. et al.
Rescue of myeloid lineage-committed preprogenitor cells from cytomegalovirus-infected bone marrow stroma.J Virol. Bd. J Virol. 1991 S. 981-984
Reddehase, Matthias Johannes; Reddehase, M. J.; Rothbard, J. B. et al.
A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytesNature. Bd. Nature. 1989 S. 651-653
Reddehase, Matthias Johannes; Reddehase, M. J.; Jonjic, S. et al.
Adoptive immunotherapy of murine cytomegalovirus adrenalitis in the immunocompromised host: CD4-helper-independent antiviral function of CD8-+ memory T lymphocytes derived from latently infected donorsJ Virol. Bd. J Virol. 1988 S. 1061-1065
Reddehase, Matthias Johannes; Reddehase, M. J.; Mutter, W. et al.
Failure in generating hemopoietic stem cells is the primary cause of death from cytomegalovirus disease in the immunocompromised host.J-Exp-Med. Bd. J-Exp-Med. 1988 S. 1645-58
Reddehase, Matthias Johannes; Reddehase, M. J.; Mutter, W. et al.
CD8-positive T lymphocytes specific for murine cytomegalovirus-immediate-early antigens mediate protective immunityJ Virol. Bd. J Virol. 1987 S. 3102-3108
Reddehase, Matthias Johannes; Reddehase, M. J.; Mutter, W. et al.
In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infectionJ-Exp-Med. Bd. J-Exp-Med. 1987 S. 650-656