Prof. Dr. med. Markus Maeurer
FB 04 - Universitätsmedizin, Johannes Gutenberg-Universität Mainz
- 06131/39-33645
- 06131/39-35580
Höhn, H.; Jülch, M.; Pilch, H. et al.
Definition of the HLA-A2 restricted peptides recognized by human CD8+effector T cells by flow-assisted sorting of the CD8+CD45RA+CD28- T cell subpopulationClinical and experimental immunology. Bd. 131. H. 1. Oxford: Blackwell 2003 S. 102 - 110
Maeurer, Markus; Trinder, P. K. E.; Maeurer, M. J. et al.
Interleukin-7Thomson, A.W.; Lotze, M.T. (Hrsg). The Cytokine Handbook. London: Elsevier Science 2003 S. 305-345
Höhn, Hanni; Kortsik, Cornelius; Tully, Glenn et al.
Longitudinal analysis of Mycobacterium tuberculosis 19-kDa antigen-specific T cells in patients with pulmonary tuberculosis: association with disease activity and cross-reactivity to a peptide from HIVenv gp120Weinheim: Wiley VCH 2003 S. 1613 - 1623
Nilges, Katja; Höhn, Hanni; Pilch, Henryk et al.
PATHOGENESIS AND IMMUNITY - Human Papillomavirus Type 16 E7 Peptide-Directed CD8+ T Cells from Patients with Cervical Cancer Are Cross-Reactive with the Coronavirus NS2 ProteinJournal of virology. a publication of the American Society for Microbiology. Bd. 77. H. 9. Washington, DC: ASM 2003 S. 5464 - 5474
Pilch, H.; Höhn, H.; Freitag, K. et al.
CELLULAR IMMUNOLOGY - Improved Assessment of T-Cell Receptor (TCR) VB Repertoire in Clinical Specimens: Combination of TCR-CDR3 Spectratyping with Flow Cytometry-Based TCR VB Frequency AnalysisClinical and diagnostic laboratory immunology. Bd. 9. H. 2. Washington, DC: ASM 2002 S. 257 - 266
Jäger, Elke; Salter, Russell; Castelli, Chiara et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - Impact of Antigen Presentation on TCR Modulation and Cytokine Release: Implications for Detection and Sorting of Antigen-Specific CD8+ T Cells Using HLA-A2 Wild-Type or HLA-A2 Mutant Tetrameric ComplexesThe journal of immunology. official journal of the American Association of Immunologists. Bd. 168. H. 6. Bethesda, Md.: American Assoc. of Immunologists 2002 S. 2766 - 2772
Maeurer, Markus; Maeurer, M. J.; Necker, A. et al.
Detection of Melan-A/MART-1 specific T-cells expressing low or high levels of CD8 by HLA-A2 tetramers can be optimized by altering bound peptide or CD8 binding siteInt. J. Cancer. Bd. Int. J. Cancer. 2002 S. 64-71
Pilch, H.; Höhn, H.; Neukirch, C. et al.
EXPERIMENTAL CLINICAL INVESTIGATION - Antigen-Driven T-Cell Selection in Patients with Cervical Cancer as Evidenced by T-Cell Receptor Analysis and Recognition of Autologous TumorClinical and diagnostic laboratory immunology. Bd. 9. H. 2. Washington, DC: ASM 2002 S. 267 - 278
Hoffmann, Thomas K.; Loftus, Douglas J.; Nakano, Koji et al.
HOST DEFENSE - The Ability of Variant Peptides to Reverse the Nonresponsiveness of T Lymphocytes to the Wild-Type Sequence p53264-272 EpitopeThe journal of immunology. official journal of the American Association of Immunologists. Bd. 168. H. 3. Bethesda, Md.: American Assoc. of Immunologists 2002 S. 1338 - 1347
Höhn, H.; Neukirch, C.; Freitag, K. et al.
Longitudinal analysis of the T-cell receptor (TCR)-VA and -VB repertoire in CD8+ T cells from individuals immunized with recombinant hepatitis B surface antigenClinical and experimental immunology. Bd. 129. H. 2. Oxford: Blackwell 2002 S. 309 - 317
Maeurer, Markus; Fiedler, T.; Walter, W. et al.
Regulation of CD1d expression in murine tumor cells: Escape from immunosurveillance or alternate target moleculesInt. J. Cancer. Bd. Int. J. Cancer. 2002 S. 389-397
Maeurer, Markus; Castelli, C.; Maeurer, M. J.
The T-cell response in patients with cancerAdv. Cancer Res. 2002 S. 149-193
Jäger, Elke; Höhn, Hauni; Necker, Artje et al.
TUMOR IMMUNOLOGY - Peptide-specific CD8+ T-cell evolution in vivo: Response to peptide vaccination with Melan-A-MART-1 Published online 4 January 2002International journal of cancer. Bd. 98. H. 3. New York, NY: Wiley-Liss 2002
Maeurer, Markus; Höhn, Hanni; Castelli, Chiara et al.
Antigen recognition by T cells: a strong sense of structureTrends in immunology. Bd. 22. H. 11. Oxford: Elsevier 2001 S. 599 - 600
Ritz, U.; Momburg, F.; Pilch, H. et al.
Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma.International journal of oncology. Bd. 19. H. 6. Athens, Ga.: Editorial Acad. 2001 S. 1211 - 1220
Tully, Glenn; Jäger, Elke; Maeurer, Markus J.
Detection of antigen-specific T-cells with MHC-peptide-tetramer-complexesClinical and applied immunology reviews. official journal of the Association of Medical Laboratory Immunologists ; CAIR. Bd. 2. H. 6. Amsterdam [u.a.]: Elsevier 2001 S. 345 - 356
Maeurer, Markus; Höhn, H.; Kortsik, C. et al.
HLA-A2 restricted and M. tuberculosis 19 kDa antigen-specific CD8+ T-cell responses are oligoclonal and exhibit a Tc2 cytokine secretion patternImmunology. Bd. Immunology. 2001 S. 278-288
Walter, Wolfgang; Scheuer, Claudia; Loos, Michael et al.
MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY - H2-Mb1 and H2-Mb2 heterodimers equally promote CLIP removal in I-Aq molecules from autoimmune-prone DBA-1 mice.The journal of biological chemistry. JBC. Bd. 276. H. 14. Bethesda, Md.: ASBMB 2001 S. 11086 - 11091
Pilch, H.; Günzel, S.; Schäffer, U. et al.
Original papers - Human Papillomavirus (HPV) DNA in primary cervical cancer and in cancer free pelvic lymph nodes -- correlation with clinico-pathological parameters and prognostic significance (in English)Zentralblatt für Gynäkologie. Bd. 123. H. 2. Heidelberg: Barth 2001 S. 91 - 101
Sun, Y.; Song, M.; Maeurer, M.J. et al.
Segregation of Effector Mechanisms in a Tumour-Specific CD8+T-Cell Clone Correlates with CD30 ExpressionScandinavian journal of immunology. the official journal of the Scandinavian Society for Immunology. Bd. 54. H. 3. Oxford [u.a.]: Blackwell 2001 S. 314 - 320
Pilch, H.; Günzel, S.; Schäffer, U. et al.
The presence of HPV DNA in cervical cancer: Correlation with clinico-pathologic parameters and prognostic significance: 10 years experience at the Department of Obstetrics and Gynecology of the MainzUniversityInternational journal of gynecological cancer. official journal of the International Gynecological Cancer Society. Bd. 11. H. 1. Boston, Mass. [u.a.]: Blackwell 2001 S. 39 - 48
Maeurer, Markus; Lüder, C. G.; Walter, W. et al.
Toxoplasma gondii down-regulates major histocompatibility complex class II gene expression in and antigen presentation by murine macrophages via intereference with nuclear translocation of STAT1alphaEur. J. Immunol. Bd. Eur. J. Immunol. 2001 S. 1475-1484
Seliger, Barbara; Maeurer, Markus J.; Ferrone, Soldano
Antigen-processing machinery breakdown and tumor growthImmunology today. Bd. 21. H. 9. Cambridge: Elsevier 2000 S. 455 - 464
Jäger, E.; Maeurer, M.; Höhn, H. et al.
CANCER THERAPY - Clonal expansion of Melan A-specific cytotoxic T lymphocytes in a melanoma patient responding to continued immunization with melanoma-associated peptidesInternational journal of cancer. Bd. 86. H. 4. New York, NY: Wiley-Liss 2000 S. 538 - 547
Walter, Wolfgang; Scheuer, Claudia; Lingnau, Karen et al.
H2-M, a facilitator of MHC class II peptide loading, and its negative modulator H2-O are differentially expressed in response to proinflammatory cytokinesImmunogenetics. Bd. 51. H. 10. Berlin: Springer 2000 S. 794 - 804
Walter, W.; Lingnau, K.; Schmitt, E. et al.
MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance?The British journal of cancer. the clinical and scientific journal of The Cancer Research Campaign ; BJC. Bd. 83. H. 9. Basingstoke: Nature Publishing Group 2000 S. 1192 - 1201
Maeurer, Markus J.; Trinder, Peter; Hommel, Gerhard et al.
MICROBIAL IMMUNITY AND VACCINES - Interleukin-7 or Interleukin-15 Enhances Survival of Mycobacterium tuberculosis-Infected MiceInfection and immunity. IAI ; a publication of the American Society for Microbiology. Bd. 68. H. 5. Washington, DC: Soc. 2000 S. 2962 - 2970
Pilch, H.; Günzel, S.; Freitag, C. et al.
Originals - Expansion of the CD8 + CD45RA + CD27 - CD28 - T-Cell Subset in Patients with HPV-Associated Cervical Cancer and its PrecursorsGeburtshilfe und Frauenheilkunde. German journal of obstetrics and gynecology. Bd. 60. H. 9. Stuttgart: Thieme 2000 S. 464 - 468
Höhn, Hanni; Pilch, Henryk; Günzel, Susanne et al.
PATHOGENESIS AND IMMUNITY - Human Papillomavirus Type 33 E7 Peptides Presented by HLA-DR*0402 to Tumor-Infiltrating T Cells in Cervical CancerJournal of virology. a publication of the American Society for Microbiology. Bd. 74. H. 14. Washington, DC: ASM 2000 S. 6632 - 6636
Maeurer, M.J.; Seliger, B.; Trinder, P. et al.
BASIC IMMUNOLOGY - Interleukin-15 in Mycobacterial Infection of Antigen-Presenting CellsScandinavian journal of immunology. the official journal of the Scandinavian Society for Immunology. Bd. 50. H. 3. Oxford [u.a.]: Blackwell 1999 S. 281 - 289
Höhn, Hanni; Pilch, Henryk; Günzel, Susanne et al.
CLINICAL IMMUNOLOGY - CD4+ Tumor-Infiltrating Lymphocytes in Cervical Cancer Recognize HLA-DR-Restricted Peptides Provided by Human Papillomavirus-E7The journal of immunology. official journal of the American Association of Immunologists. Bd. 163. H. 10. Bethesda, Md.: American Assoc. of Immunologists 1999 S. 5715 - 5722
Walter, W.; Loos, M.; Maeurer, M.J.
Differential expression of alternative H2-M isoforms in B cells, dendritic cells and macrophages by proinflammatory cytokinesMolecular immunology. Bd. 36. H. 11. Amsterdam [u.a.]: Elsevier 1999 S. 733 - 744
Jäger, E.; Höhn, H.; Karbach, J. et al.
Experimental Cancer - Cytotoxic T lymphocytes define multiple peptide isoforms derived from the melanoma-associated antigen MART-1-Melan-AInternational journal of cancer. Bd. 81. H. 6. New York, NY: Wiley-Liss 1999 S. 979 - 984
Maeurer, Markus; Höhn, H.; Reichert, T. et al.
Monoclonal TCR mRNA transcripts are preferentially detected in the TCR variable alpha chain in CD8+ T-lymphocytes. Implications for immunomonitoringJ. Mol. Med. Bd. J. Mol. Med. 1999 S. 139-144
Maeurer, M.J.; Walter, W.; Martin, D. et al.
Interleukin-7 (IL-7) in Colorectal Cancer: IL-7 is Produced by Tissues from Colorectal Cancer and Promotes Preferential Expansion of Tumour Infiltrating LymphocytesScandinavian journal of immunology. the official journal of the Scandinavian Society for Immunology. Bd. 45. H. 2. Oxford [u.a.]: Blackwell 1997 S. 182 - 192
Maeurer, Markus; Maeurer, M. J.; Zitvogel, L. et al.
. Human intestinal Vgamma-1+ T-cells obtained from patients with colorectal cancer respond exclusively to SEB, but not to SEANat. Immunol. Bd. Nat. Immunol. 1996 S. 188-197
Maeurer, Markus J.; Chan, Huei-Wie; Karbach, Julia et al.
Amino acid substitutions at position 97 in HLA-A2 segregate cytolysis from cytokine release in MART-1-Melan-A peptide AAGIGILTV-specific cytotoxic T lymphocytesEuropean journal of immunology. Bd. 26. H. 11. Weinheim: Wiley VCH 1996 S. 2613 - 2623
Maeurer, Markus J.; Martin, Dina; Elder, Elaine et al.
Detection of Naturally Processed and HLA-A1-presented Melanoma T-Cell Epitopes Defined by CD8+ T-Cells' Release of Granulocyte-Macrophage Colony-stimulating Factor but not by CytolysisClinical cancer research. an official journal of the American Association for Cancer Research. Bd. 2. H. 1. Philadelphia, Pa. [u.a.]: AACR 1996 S. 87 - 96
Maeurer, MarkusJ; Martin, Dina; Walter, Wolfgang et al.
Human intestinal Vd1 + T lymphocytes recognize tumor cells of epithelial originThe journal of experimental medicine. JEM. Bd. 183. H. 4. New York, NY: Rockefeller Univ. Press 1996 S. 1681 - 1696
Zitvogel, Laurence; Robbins, Paul D.; Storkus, Walter J. et al.
Interleukin-12 and B7.1 co-stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumorsEuropean journal of immunology. Bd. 26. H. 6. Weinheim: Wiley VCH 1996 S. 1335 - 1341
Mazzocchi, Arabella; Storkus, Walter J.; Traversari, Catia et al.
Multiple Melanoma-Associated Epitopes Recognized by HLA-A3-Restricted CTLs and Shared by Melanomas but Not MelanocytesThe journal of immunology. official journal of the American Association of Immunologists. Bd. 157. H. 7. Bethesda, Md.: American Assoc. of Immunologists 1996 S. 3030 - 3038
Maeurer, M.; Storkus, W.; Kirkwood, J. et al.
New treatment options for patients with melanoma: review of melanoma - derived T-cell epitope-based peptide vaccinesMelanoma Res. Bd. Melanoma Res. 1996 S. 11-24
Bernhard, H.; Maeurer, M.J.; Jäger, E. et al.
Recognition of Human Renal Cell Carcinoma and Melanoma by HLA-A2-Restricted Cytotoxic T Lymphocytes is Mediated by Shared Peptide Epitopes and Up-Regulated by Interferon-gScandinavian journal of immunology. the official journal of the Scandinavian Society for Immunology. Bd. 44. H. 3. Oxford [u.a.]: Blackwell 1996 S. 285 - 292
Bernhard, H.; Jäger, E.; Maeurer, M.J. et al.
Tumor associated antigens in human renal cell carcinoma: MHC restricted recognition by cytotoxic T lymphocytesTissue antigens. histocompatibility and immunogenetics. Bd. 48. H. 1. Oxford: Blackwell Munksgaard 1996 S. 22 - 31
Maeurer, Markus J.; Gollin, Susanne M.; Storkus, Walter J. et al.
Tumor Escape from Immune Recognition: Loss of HLA-A2 Melanoma Cell Surface Expression Is Associated with a Complex Rearrangement of the Short Arm of Chromosome 6Clinical cancer research. an official journal of the American Association for Cancer Research. Bd. 2. H. 4. Philadelphia, Pa. [u.a.]: AACR 1996 S. 641 - 652
Maeurer, M.J.; Gollin, S.M.; Martin, D. et al.
Tumor escape from immune recognition. Lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1-Melan-A antigenThe journal of clinical investigation. JCI ; the publication of the American Society for Clinical Investigation. Bd. 98. H. 7. Ann Arbor, Mich.: American Society for Clinical Investigation 1996 S. 1633 - 1641
Maeurer, M.; Hurd, S.; Martin, D. et al.
Cytolytic T-cell clones define HLA-A2 restricted human cutaneous melanoma peptide epitopes - correlation with T-cell receptor usageCancer J. Sci. Am. Bd. Cancer J. Sci. Am. 1995 S. 162-170
Maeurer, Markus; Maeurer, M. J.; Martin, D. M. et al.
Evidence for shared TCR usage in CTL recognizing HLA-A2 presented antigens shared by melanoma and melanocytesImmunology Today. Bd. Immunology Today. 1995 S. 603-604
Maeurer, M.J.; Martin, D.M.; Castelli, C. et al.
Host immune response in renal cell cancer: Interleukin-4 (IL-4) and IL-10 mRNA are frequently detected in freshly collected tumor-infiltrating lymphocytesCancer immunology immunotherapy. CII ; other biological response modification. Bd. 41. H. 2. Berlin: Springer 1995 S. 111 - 121
Castelli, Chiara; Storkus, Walter J.; Maeurer, Markus J. et al.
Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytesThe journal of experimental medicine. JEM. Bd. 181. H. 1. New York, NY: Rockefeller Univ. Press 1995 S. 363 - 368