Univ.-Prof. Dr. Gerd Dannhardt
Institut für Pharmazie und Biochemie - Therapeutische Lebenswissenschaften, Johannes Gutenberg-Universität Mainz
- 06131/39-25742/25728 (Sekr.)
- 06131/39-23062
Peifer, C.; Dannhardt, G.
A Novel Quantitative Chick Embryo Assay as an Angiogenesis Model Using Digital Image Analysis.Anticancer research. international journal of cancer research and treatment. Bd. 24. H. 3. Kapandriti: International Inst. of Anticancer Research 2004 S. 1545 - 1552
Dannhardt, G.; Kiefer, W.
Coxibs and central processing of pain - an updatePharmacology. Bd. Pharmacology. 2004
Dannhardt, G.; Ulbrich, H.; Prech, P. et al.
Development of a computerized in vitro assay for the investigation of antiadhesive compoundsEur. J. Pharm. Sci. Bd. Eur. J. Pharm. Sci. 2004
Kiefer, W.; Dannhardt, G.
Novel Insights and Therapeutical Applications in the Field of Inhibitors of COX-2Current medicinal chemistry. the new international journal for timely in-depth reviews in medicinal chemistry. Bd. 11. H. 24. Schiphol: Bentham 2004 S. 3147 - 3162
Jansen, Michaela; Dannhardt, Gerd
Antagonists and agonists at the glycine site of the NMDA receptor for therapeutic interventionsEuropean journal of medicinal chemistry. Bd. 38. H. 7. Paris: EDIFOR 2003 S. 661 - 670
Banwell, M. G.; Bezos, A.; Chand, S. et al.
Convergent synthesis and preliminary biological evaluations of the stilbenolignan (+)-aiphanol and various congenersOrg. Biomol. Chem. Bd. Org. Biomol. Chem. 2003 S. 1-5
Jansen, M.; Potschka, H.; Brandt, C. et al.
Hydantoin-Substituted 4,6-Dichloroindole-2-carboxylic Acids as Ligands with High Affinity for the Glycine Binding Site of the NMDA ReceptorJournal of medicinal chemistry. Bd. 46. H. 1. Easton, Pa.: American Chemical Society 2003 S. 64 - 73
Bohme, T.M.; Keim, C.; Kreutzmann, K. et al.
Structure-Activity Relationships of Dimethindene Derivatives as New M2-Selective Muscarinic Receptor AntagonistsJournal of medicinal chemistry. Bd. 46. H. 5. Easton, Pa.: American Chemical Society 2003 S. 856 - 867
Piel, Markus; Schirrmacher, Ralf; Höhnemann, Sabine et al.
Synthesis and evaluation of 5,7-dichloro-4-(3-{4-(4-(2-(18F)fluoroethyl)-piperazin-1-yl)-phenyl- }-ureido)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid as a potential NMDA ligand to study glutamatergic neurotransmission in vivoJournal of labelled compounds & radiopharmaceuticals. Bd. 46. H. 7. London: Wiley 2003 S. 645 - 660
Jansen, Michaela; Dannhardt, Gerd
Variations of acidic functions at position 2 and substituents at positions 4, 5 and 6 of the indole moiety and their effect on NMDA-glycine site affinityEuropean journal of medicinal chemistry. Bd. 38. H. 10. Paris: EDIFOR 2003 S. 855 - 866
Dannhardt, Gerd; Fiebich, Bernd L.; Schweppenhäuser, Johannes
COX-1-COX-2 inhibitors based on the methanone moietyEuropean journal of medicinal chemistry. Bd. 37. H. 2. Paris: EDIFOR 2002 S. 147 - 162
Dannhardt, G.; Kiefer, W.
COX-2 inhibition and the control of painCurr. Opin. Invest. Drugs. Bd. Curr. Opin. Invest. Drugs. 2002 S. 1348-1358
Ulbrich, Holger; Fiebich, Bernd; Dannhardt, Gerd
Cyclooxygenase-1-2 (COX-1-COX-2) and 5-lipoxygenase (5-LOX) inhibitors of the 6,7-diaryl-2,3-1H-dihydropyrrolizine typeEuropean journal of medicinal chemistry. Bd. 37. H. 12. Paris: EDIFOR 2002 S. 953 - 960
Danz, Henning; Stoyanova, Stefka; Thomet, Olivier A. et al.
Inhibitory Activity of Tryptanthrin on Prostaglandin and Leukotriene SynthesisPlanta medica. natural products and medicinal plant research ; official organ of the Society for Medicinal Plant Research. Bd. 68. H. 10. Stuttgart [u.a.]: Thieme 2002 S. 875 - 880
Ulbrich, Holger; Dannhardt, Gerd
MEDIZINISCHE CHEMIE - NSAR: Klassifizierung und WirkspektrumPharmazie in unserer Zeit. Wissenschaft, Bildung und Weiterbildung. Bd. 31. H. 2. Weinheim: Wiley-VCH 2002 S. 146 - 155
Dannhardt, Gerd; Kiefer, Werner
Cyclooxygenase inhibitors - current status and future prospectsEuropean journal of medicinal chemistry. Bd. 36. H. 2. Paris: EDIFOR 2001 S. 109 - 126
Böhme, Thomas M.; Keim, Christine; Dannhardt, Gerd et al.
Design and pharmacology of quinuclidine derivatives as M2-selective muscarinic receptor ligandsBioorganic & medicinal chemistry letters. a Tetrahedron publication for rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry and related disciplines. Bd. 11. H. 9. New York, NY [u.a.]: Pergamon, Elsevier Science 2001 S. 1241 - 1244
Ulbrich, H.; Dannhardt, G.
In-vitro test system for the evaluation of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors based on a single HPLC run with UV detection using bovine aortic coronary endothelial cells (BAECs)Inflamm. Res. Bd. Inflamm. Res. 2001 S. 262-269
Kohl, B.K.; Dannhardt, G.
The NMDA Receptor Complex: A Promising Target for Novel Antiepileptic StrategiesCurrent medicinal chemistry. the new international journal for timely in-depth reviews in medicinal chemistry. Bd. 8. H. 11. Schiphol: Bentham 2001 S. 1275 - 1290
Jacobs, Christoph; Frotscher, Martin; Dannhardt, Gerd et al.
Articles - 1-Imidazolyl(alkyl)-Substituted Di- and Tetrahydroquinolines and Analogues: Syntheses and Evaluation of Dual Inhibitors of Thromboxane A2 Synthase and AromataseJournal of medicinal chemistry. Bd. 43. H. 9. Easton, Pa.: American Chemical Society 2000 S. 1841 - 1851
Dannhardt, G.; Kohl, B.K.
Benzimidazoles as ligands for the glycine-site of the NMDA receptor: Synthesis, radioligand and binding-studies and structure-activity relationshipsPharmaceutical and pharmacological letters. PPL. Bd. 10. H. 1. Stuttgart: Medpharm 2000 S. 1 - 4
Tumiatti, V.; Wehrle, J.; Hildebrandt, C. et al.
CNS-active Drugs . Hypnotics . Psychotropics . Sedatives - Muscarinic Properties of Compounds Related to Arecaidine Propargyl EsterArzneimittel-Forschung. Veröffentlichungen über Forschungs- und Prüfungsergebnisse insbesondere neu zu entwickelnder Arzneistoffe einschließlich neuer wissenschaftlicher Erkenntnisse von bereits auf dem Markt sich befindenden Präparaten. Bd. 50. H. 1. Aulendorf: Editio-Cantor-Verl. 2000
Dannenberg, Gerd; Hahn, Linda; Dannhardt, Gerd
COX-2-Inhibitoren: Aktueller Stand und AusblickWeinheim: Wiley-VCH 2000 S. 100 - 106
Dannhardt, Gerd; Gruchalla, Markus v.; Kohl, Beate K. et al.
FULL PAPERS - A Novel Series of 2-Carboxytetrahydroquinolines Provides New Insights into the Eastern Region of Glycine Site NMDA AntagonistsArchiv der Pharmazie. chemistry in life sciences. Bd. 333. H. 8. Weinheim: Wiley-VCH 2000 S. 267 - 274
Dannhardt, Gerd; Kohl, Beate K.
FULL PAPERS - Benzimidazoles as NMDA Glycine-Site Antagonists: Study on the Structural Requirements in 2-Position of the LigandArchiv der Pharmazie. chemistry in life sciences. Bd. 333. H. 5. Weinheim: Wiley-VCH 2000 S. 123 - 129