Prof. Dr. rer. nat. habil. Edgar Schmitt
FB 04 - Universitätsmedizin, Johannes Gutenberg-Universität Mainz
- 06131/39-33228
- 06131/39-35688
Lohoff, Michael; Duncan, Gordon S.; Ferrick, David et al.
Articles - Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cellsThe journal of experimental medicine. JEM. Bd. 192. H. 3. New York, NY: Rockefeller Univ. Press 2000 S. 325 - 336
Hültner, Lothar; Kölsch, Stephan; Stassen, Michael et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - In Activated Mast Cells, IL-1 Up-Regulates the Production of Several Th2-Related Cytokines Including IL-9The journal of immunology. official journal of the American Association of Immunologists. Bd. 164. H. 11. Bethesda, Md.: American Assoc. of Immunologists 2000 S. 5556 - 5563
Stassen, Michael; Arnold, Martina; Hültner, Lothar et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - Murine Bone Marrow-Derived Mast Cells as Potent Producers of IL-9: Costimulatory Function of IL-10 and kit Ligand in the Presence of IL-1The journal of immunology. official journal of the American Association of Immunologists. Bd. 164. H. 11. Bethesda, Md.: American Assoc. of Immunologists 2000 S. 5549 - 5555
Müller, Gabi; Müller, Anke; Jonuleit, Helmut et al.
Fetal calf serum-free generation of functionally active murine dendritic cells suitable for in vivo therapeutic approachesThe Journal of investigative dermatology. Bd. 114. H. 1. New York, NY: Nature Publishing Group 2000 S. 142 - 149
Walter, Wolfgang; Scheuer, Claudia; Lingnau, Karen et al.
H2-M, a facilitator of MHC class II peptide loading, and its negative modulator H2-O are differentially expressed in response to proinflammatory cytokinesImmunogenetics. Bd. 51. H. 10. Berlin: Springer 2000 S. 794 - 804
Jonuleit, Helmut; Schmitt, Edgar; Schuler, Gerold et al.
Induction of interleukin 10-producing, nonproliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cellsThe journal of experimental medicine. JEM. Bd. 192. H. 9. New York, NY: Rockefeller Univ. Press 2000 S. 1213 - 1222
Walter, W.; Lingnau, K.; Schmitt, E. et al.
MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance?The British journal of cancer. the clinical and scientific journal of The Cancer Research Campaign ; BJC. Bd. 83. H. 9. Basingstoke: Nature Publishing Group 2000 S. 1192 - 1201
Chuvpilo, S.; Zimmer, M.; Kerstan, A. et al.
Articles - Alternative Polyadenylation Events Contribute to the Induction of NF-ATc in Effector T CellsImmunity. Bd. 10. H. 2. Cambridge, Mass.: Cell Press 1999 S. 261 - 270
Knolle, Percy A.; Germann, Tieno; Treichel, Ulrich et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - Endotoxin Down-Regulates T Cell Activation by Antigen-Presenting Liver Sinusoidal Endothelial CellsThe journal of immunology. official journal of the American Association of Immunologists. Bd. 162. H. 3. Bethesda, Md.: American Assoc. of Immunologists 1999 S. 1401 - 1407
Neurath, M.F.; Hildner, K.; Becker, C. et al.
Experimental models of autoimmunity - Methotrexate specifically modulates cytokine production by T cells and macrophages in murine collagen-induced arthritis (CIA): A mechanism for methotrexate-mediated immunosuppressionClinical and experimental immunology. Bd. 115. H. 1. Oxford: Blackwell 1999 S. 42 - 55
Steinborn, A.; Sohn, C.; Sayehli, C. et al.
Immunology of reproduction - Spontaneous labour at term is associated with fetal monocyte activationClinical and experimental immunology. Bd. 117. H. 1. Oxford: Blackwell 1999 S. 147 - 152
Knolle, P.A.; Schmitt, E.; Jin, S. et al.
LIVER, PANCREAS, AND BILIARY TRACT - Induction of Cytokine Production in Naive CD4+ T Cells by Antigen-Presenting Murine Liver Sinusoidal Endothelial Cells but Failure to Induce Differentiation Toward Th1 CellsGastroenterology. official publication of the American Gastroenterological Association. Bd. 116. H. 6. Philadelphia, Pa.: Elsevier 1999 S. 1428 - 1440
Lingnau, Karen; Hoehn, Petra; Kerdine, Saadia et al.
CELLULAR IMMUNOLOGY AND IMMUNE REGULATION - IL-4 in Combination with TGF-b Favors an Alternative Pathway of Th1 Development Independent of IL-12The journal of immunology. official journal of the American Association of Immunologists. Bd. 161. H. 9. Bethesda, Md.: American Assoc. of Immunologists 1998 S. 4709 - 4718
Schmitt, E.; Rüde, E.; Germann, T.
The Immunostimulatory Function of IL-12 in T-Helper Cell Development and Its Regulation by TGF-b, IFN-g and IL-4Chemical immunology. Bd. 68. Basel: Karger 1997 S. 70 - 85
Palm, N.; Germann, T.; Goedert, S. et al.
Co- Development of Naive CD4+ Cells towards T Helper Type 1 or T Helper Type 2 Cells Induced by a Combination of IL-12 and IL-4Immunobiology. experimental and clinical. Bd. 196. H. 5. Jena [u.a.]: Elsevier 1996 S. 475 - 484
Goedert, Sigrid; Germann, Tieno; Hoehn, Petra et al.
Th1 Development of Naive CD4+ T Cells Is Inhibited by Co-Activation with Anti-CD4 Monoclonal AntibodiesThe journal of immunology. official journal of the American Association of Immunologists. Bd. 157. H. 2. Bethesda, Md.: American Assoc. of Immunologists 1996 S. 566 - 573
Huels, C.; Germann, T.; Goedert, S. et al.
Co-activation of naive CD4+ T cells and bone marrow-derived mast cells results in the development of Th2 cellsInternational immunology. II. Bd. 7. H. 4. Oxford: Univ. Press 1995 S. 525 - 532
Hoehn, Petra; Goedert, Sigrid; Germann, Tieno et al.
Opposing Effects of TGF-b2 on the Th1 cell Development of Naive CD4+ T Cells Isolated from Different Mouse StrainsThe journal of immunology. official journal of the American Association of Immunologists. Bd. 155. H. 8. Bethesda, Md.: American Assoc. of Immunologists 1995 S. 3788 - 3793
Germann, T.; Rüde, E.; Schmitt, E.
The influence of IL12 on the development of Th1 and Th2 cells and its adjuvant effect for humoral immune responsesResearch in immunology. Bd. 146. H. 7. Amsterdam [u.a.]: Elsevier 1995 S. 481 - 485
Schmitt, Edgar; Germann, Tieno; Goedert, Sigrid et al.
IL-9 Production of Naive CD4+ T Cells Depends on IL-2, Is Synergistically Enhanced by a Combination of TGF-b and IL-4, and Is Inhibited by IFN-gThe journal of immunology. official journal of the American Association of Immunologists. Bd. 153. H. 9. Bethesda, Md.: American Assoc. of Immunologists 1994 S. 3989 - 3996
Schmitt, E.; Hoehn, P.; Huels, C. et al.
T helper type 1 development of naive CD4+ T cells requires the coordinate action of interleukin-12 and interferon-g and is inhibited by transforming growth factor-bEuropean journal of immunology. Bd. 24. H. 4. Weinheim: Wiley VCH 1994 S. 793 - 798