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Institut für translationale Onkologie (TRON)

Klinikum / Johannes Gutenberg-Universität Mainz

Publikationen
Ergebnisse pro Seite:  50

Kaps, Leonard; Huppertsberg, Anne; Choteschovsky, Niklas et al.

pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 119. H. 12. 2022


Krienke, Christina; Kolb, Laura; Diken, Elif et al.

A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis

SCIENCE. Bd. 371. H. 6525. 2021 S. 146-+


Alishah, Khadijeh; Birtel, Matthias; Masoumi, Elham et al.

CRISPR/Cas9-mediated TGF beta RII disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells in vitro

JOURNAL OF TRANSLATIONAL MEDICINE. Bd. 19. H. 1. 2021


Kappel, Cinja; Seidl, Christine; Medina-Montano, Carolina et al.

Density of Conjugated Antibody Determines the Extent of Fc Receptor Dependent Capture of Nanoparticles by Liver Sinusoidal Endothelial Cells

ACS NANO. Bd. 15. H. 9. 2021 S. 15191-15209


Formes, Henning; Bernardes, Joana P.; Mann, Amrit et al.

The gut microbiota instructs the hepatic endothelial cell transcriptome

ISCIENCE. Bd. 24. H. 10. 2021


Salomon, Nadja; Vascotto, Fulvia; Selmi, Abderaouf et al.

A liposomal RNA vaccine inducing neoantigen-specific CD4(+)T cells augments the antitumor activity of local radiotherapy in mice

ONCOIMMUNOLOGY. Bd. 9. H. 1. 2020


Reinhard, Katharina; Rengstl, Benjamin; Oehm, Petra et al.

An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors

SCIENCE. Bd. 367. H. 6476. 2020 S. 446-+


Sahin, Ugur; Oehm, Petra; Derhovanessian, Evelyna et al.

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

NATURE. Bd. 585. H. 7823. 2020 S. 107-+


Sorn, Patrick; Holtstraeter, Christoph; Loewer, Martin et al.

ArtiFuse-computational validation of fusion gene detection tools without relying on simulated reads

BIOINFORMATICS. Bd. 36. H. 2. 2020 S. 373-379


Beck, Jan David; Birtel, Matthias; Haefner, Erik et al.

CIMT 2019: report on the 17th Annual Meeting of the Association for Cancer Immunotherapy

HUMAN VACCINES & IMMUNOTHERAPEUTICS. Bd. 16. H. 4. 2020 S. 808-815


Frank, Annika M.; Braun, Angela H.; Scheib, Lea et al.

Combining T-cell-specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors

BLOOD ADVANCES. Bd. 4. H. 22. 2020 S. 5702-5715


Laible, Mark; Aulmann, Sebastian; Etzrodt, Alfred et al.

Comparison of MammaTyper (R) RT-qPCR based subtyping with simulated breast cancer prognostic signatures

CANCER RESEARCH. Bd. 80. H. 4. 2020


Bresadola, Luisa; Kong, Anthony; Loewer, Martin et al.

Comprehensive Genomic and Transcriptomic Analysis of Primary and Recurrent Head and Neck Cancers

ONCOLOGY RESEARCH AND TREATMENT. Bd. 43. 2020 S. 230-230


Sahin, Ugur; Muik, Alexander; Derhovanessian, Evelyna et al.

COVID-19 vaccine BNT162b1 elicits human antibody and T(H)1 T cell responses

NATURE. Bd. 586. H. 7830. 2020 S. 594-+


Kranz, Lena Mareen; Schroers, Barbara; Bukur, Thomas et al.

Evaluation of systemic RNA-based cancer vaccine induced T-cell responses via mouse T-cell receptor (TCR) profiling.

CANCER IMMUNOLOGY RESEARCH. Bd. 8. H. 4. 2020 S. 111-112


Heimes, A. S.; Versantvoort, C.; Hensen, S. et al.

Identification and analysis of tumor-associated antigens in triple-negative breast cancer (TNBC)

GEBURTSHILFE UND FRAUENHEILKUNDE. Bd. 80. H. 06. 2020 S. E37-E37


Schroers, Barbara; Boegel, Sebastian; Albrecht, Christian et al.

Multi-Omics Characterization of the 4T1 Murine Mammary Gland Tumor Model

FRONTIERS IN ONCOLOGY. Bd. 10. 2020


Schoepf, Bernd; Weissensteiner, Hansi; Schaefer, Georg et al.

OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation

NATURE COMMUNICATIONS. Bd. 11. H. 1. 2020


Alberg, Irina; Kramer, Stefan; Schinnerer, Meike et al.

Polymeric Nanoparticles with Neglectable Protein Corona

SMALL. Bd. 16. H. 18. 2020


Becker, Sara; Fink, Annette; Podlech, Juergen et al.

Positive Role of the MHC Class-I Antigen Presentation Regulator m04/gp34 of Murine Cytomegalovirus in Antiviral Protection by CD8 T Cells

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. Bd. 10. 2020


Heimes, Anne-Sophie; Haertner, Franziska; Almstedt, Katrin et al.

Prognostic Significance of Interferon-gamma and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 21. H. 19. 2020


Diken, Mustafa; Kepp, Oliver; Brodsky, Arthur N.

Translating Science into Survival: Report on the Fifth International Cancer Immunotherapy Conference

CANCER IMMUNOLOGY RESEARCH. Bd. 8. H. 1. 2020 S. 3-6


Kim, Yong Ook; Gorres, Sebastian; Diken, Mustafa et al.

A COLLAGEN-TARGETED NEAR INFRARED SPECTROSCOPY AND POSITRON EMISSION TOMOGRAPHY CONTRAST AGENT FOR LIVER FIBROSIS IMAGING

HEPATOLOGY. Bd. 70. 2019 S. 85A-85A


Vormehr, Mathias; Tuereci, Oezlem; Sahin, Ugur

Harnessing Tumor Mutations for Truly Individualized Cancer Vaccines

Annual Review of Medicine. Bd. 70. 2019 S. 395-407


Vascotto, Fulvia; Petschenka, Jutta; Walzer, Kerstin C. et al.

Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+T cell response

ONCOIMMUNOLOGY. Bd. 8. H. 7. 2019


Siewert, C.; Haas, H.; Nawroth, T. et al.

Investigation of charge ratio variation in mRNA - DEAE-dextran polyplex delivery systems

BIOMATERIALS. Bd. 192. 2019 S. 612-620


Foerster, Friedrich; Boegel, Sebastian; Heck, Rosario et al.

Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma liver metastasis is mediated by NK cells

ONCOIMMUNOLOGY. Bd. 7. H. 4. 2018


Pektor, Stefanie; Hilscher, Lina; Walzer, Kerstin C. et al.

In vivo imaging of the immune response upon systemic RNA cancer vaccination by FDG-PET

EJNMMI RESEARCH. Bd. 8. 2018


Molokanova, Olena; Schoenig, Kai; Weng, Shih-Yen et al.

Inducible knockdown of procollagen I protects mice from liver fibrosis and leads to dysregulated matrix genes and attenuated inflammation

MATRIX BIOLOGY. Bd. 66. 2018 S. 34-49


Rosigkeit, Sebastian; Meng, Martin; Grunwitz, Christian et al.

Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice

MOLECULAR PHARMACEUTICS. Bd. 15. H. 9. 2018 S. 3909-3919


Schmidt, Marcus; Weyer-Elberich, Veronika; Hengstler, Jan G. et al.

Prognostic impact of CD4-positive T cell subsets in early breast cancer: a study based on the FinHer trial patient population

BREAST CANCER RESEARCH. Bd. 20. 2018


Shen, Limei; Tenzer, Stefan; Storck, Wiebke et al.

Protein corona-mediated targeting of nanocarriers to B cells allows redirection of allergic immune responses

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Bd. 142. H. 5. 2018 S. 1558-1570


Kim, Yong Ook; Park, Kyoung-Sook; Engelbogen, Nils et al.

Bimodal Targeted Near Infrared/Positron Emission Tomography Contrast Agent to Image Liver Fibrogenesis

HEPATOLOGY. Bd. 66. 2017 S. 332A-332A


Sahu, Sanjeeb Kumar; Tiwari, Neha; Pataskar, Abhijeet et al.

FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development

NATURE COMMUNICATIONS. Bd. 8. 2017


Sahin, Ugur; Derhovanessian, Evelyna; Miller, Matthias et al.

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

NATURE. Bd. 547. H. 7662. 2017 S. 222-+


Leber, Nadine; Kaps, Leonard; Aslam, Misbah et al.

SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles

JOURNAL OF CONTROLLED RELEASE. Bd. 248. 2017 S. 10-23


Molokanova, O.; Schoenig, K.; Weng, S-Y et al.

Suppression of hepatic fibrosis by efficient Col1a1 silencing using shRNA inducible mouse models

JOURNAL OF HEPATOLOGY. Bd. 66. H. 1. 2017 S. S653-S654


Jabulowsky, Robert A.; Loquai, Carmen; Diken, Mustafa et al.

A novel nanoparticular formulated tetravalent RNA cancer vaccine for treatment of patients with malignant melanoma

CANCER IMMUNOLOGY RESEARCH. Bd. 4. H. 1. 2016



Foerster, Friedrich; Bamberger, Denise; Schupp, Jonathan et al.

Dextran-based therapeutic nanoparticles for hepatic drug delivery

NANOMEDICINE. Bd. 11. H. 20. 2016 S. 2663-2677


Diken, Mustafa; Pektor, Stefanie; Miederer, Matthias

Harnessing the potential of noninvasive in vivo preclinical imaging of the immune system: challenges and prospects

NANOMEDICINE. Bd. 11. H. 20. 2016 S. 2711-2722


Waisman, Ari; Hoevelmeyer, Nadine; Diefenbach, Andreas et al.

Past, present and future of immunology in Mainz

CELLULAR IMMUNOLOGY. Bd. 308. 2016 S. 1-6


Nuhn, Lutz; Kaps, Leonard; Diken, Mustafa et al.

Reductive Decationizable Block Copolymers for Stimuli-Responsive mRNA Delivery

MACROMOLECULAR RAPID COMMUNICATIONS. Bd. 37. H. 11. 2016 S. 924-933


Kranz, Lena M.; Diken, Mustafa; Haas, Heinrich et al.

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

NATURE. Bd. 534. H. 7607. 2016 S. 396-+


Grabbe, Stephan; Haas, Heinrich; Diken, Mustafa et al.

Translating nanoparticulate-personalized cancer vaccines into clinical applications: case study with RNA-lipoplexes for the treatment of melanoma

NANOMEDICINE. Bd. 11. H. 20. 2016 S. 2723-2734


Selmi, Abderraouf; Vascotto, Fulvia; Kautz-Neu, Kordula et al.

Uptake of synthetic naked RNA by skin-resident dendritic cells via macropinocytosis allows antigen expression and induction of T-cell responses in mice

CANCER IMMUNOLOGY IMMUNOTHERAPY. Bd. 65. H. 9. 2016 S. 1075-1083


Shen, Limei; Krauthaeuser, Susanne; Fischer, Karl et al.

Vaccination with trifunctional nanoparticles that address CD8(+) dendritic cells inhibits growth of established melanoma

NANOMEDICINE. Bd. 11. H. 20. 2016 S. 2647-2662


Castle, J; Kong, A; Schmidt, M

Application of Next Generation Sequencing to Breast Cancer

Vetter, Kantelhardt (Hrsg). Tumorbiologie und Diagnostik des primären Mammakarzinoms. Bremen: UNI-MED Verlag AG 2015


Foerster, F.; Strobl, S.; Kaps, L. et al.

BALB/C AND C57/BL6 MICE EXHIBIT DIFFERENCES IN THEIR SUSCEPTIBILITY AND ANTI-TUMOR RESPONSE TO B16F10 MELANOMA LIVER METASTASIS

JOURNAL OF HEPATOLOGY. Bd. 62. 2015 S. S425-S425


Kuemmel, Andreas; Simon, Petra; Breitkreuz, Andrea et al.

Humoral immune responses of lung cancer patients against the Transmembrane Phosphatase with TEnsin homology (TPTE)

LUNG CANCER. Bd. 90. H. 2. 2015 S. 334-341