Kurzfassung

In a cooperation with several clinical departments we characterize the mutations of patients with inherited endocrine tumors. The methodology to sequence the relevant genes has been developed over the last years and is continously improved. Currently, we are changing from conventional to next generation sequencing. The aim is to improve and expand our knowledge about genotype/phenotype relations. In particular, the association of mutations with malignant rather than benign neoplasms is of...In a cooperation with several clinical departments we characterize the mutations of patients with inherited endocrine tumors. The methodology to sequence the relevant genes has been developed over the last years and is continously improved. Currently, we are changing from conventional to next generation sequencing. The aim is to improve and expand our knowledge about genotype/phenotype relations. In particular, the association of mutations with malignant rather than benign neoplasms is of major interest.» weiterlesen» einklappen