Kurzfassung

Head and neck malignancies and their treatments affect a variety of body functions, most notably breathing, swallowing, and speaking. These functions are central to most people, therefore head and neck cancer can cause significant physical, emotional, and social problems, reducing quality of life (QoL) considerably.
The primary research questions of this study are:
1.What areas of QoL are reduced or improved ( 10 point difference in an EORTC QLQ subscale) in the long-term (> 5y and 10y)...Head and neck malignancies and their treatments affect a variety of body functions, most notably breathing, swallowing, and speaking. These functions are central to most people, therefore head and neck cancer can cause significant physical, emotional, and social problems, reducing quality of life (QoL) considerably. 
The primary research questions of this study are:
1.What areas of QoL are reduced or improved (≥ 10 point difference in an EORTC QLQ subscale) in the long-term (> 5y and ≥10y) compared to reference data from HNC patients before and 1 year after treatment?
2.What areas of QoL are reduced or improved (≥ 10 point difference in an EORTC QLQ subscale) in the long-term (> 5y and ≥10y) compared to the age- and sex-matched general population?
3.Do problems with swallowing, speech, senses, dry mouth, sticky saliva, coughing, social eating, teeth, fatigue, physical functioning, and toxicity differ in survivors who received surgery alone vs. radiotherapy alone vs. surgery plus adjuvant therapy vs. multimodal treatment without surgery (adjusted for age, gender, tumour stage, site, time since diagnosis, recurrence, subsequent treatments, co-morbidity)?
The survivors (n=1,200) will be invited for a clinical visit and they will complete questionnaires.» weiterlesen» einklappen