Kurzfassung

The proposed research project aims to evaluate the bone regenerating potential of systematically-modified novel bio-inspired resorbable scaffolds designed for repair of load-bearing bone defects, in in vitro coculture model systems consisting of human microvascular endothelial cells and human osteoblasts and in in vivo studies in mice and rabbits. The goal is to identify the best combination of chemical composition of the scaffold and added growth factors or cells that will result in the...The proposed research project aims to evaluate the bone regenerating potential of systematically-modified novel bio-inspired resorbable scaffolds designed for repair of load-bearing bone defects, in in vitro coculture model systems consisting of human microvascular endothelial cells and human osteoblasts and in in vivo studies in mice and rabbits. The goal is to identify the best combination of chemical composition of the scaffold and added growth factors or cells that will result in the optimal osteogenesis, angiogenesis and neovascularization.» weiterlesen» einklappen