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ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancersSCIENCE ADVANCES. Bd. 8. H. 11. 2022
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beta 2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune EncephalomyelitisCELLS. Bd. 11. H. 14. 2022
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Dithranol as novel co-adjuvant for non-invasive dermal vaccinationNPJ VACCINES. Bd. 7. H. 1. 2022
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Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in miceBRAIN BEHAVIOR AND IMMUNITY. Bd. 106. 2022 S. 49-66
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End Group Dye-Labeled Polycarbonate Block Copolymers for Micellar (Immuno-)Drug DeliveryMACROMOLECULAR RAPID COMMUNICATIONS. 2022
Kuerten, Tabea; Ihbe, Natascha; Ueberbach, Timo et al.
GABA(A) Receptor-Stabilizing Protein Ubqln1 Affects Hyperexcitability and Epileptogenesis after Traumatic Brain Injury and in a Model of In Vitro Epilepsy in MiceINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 23. H. 7. 2022
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GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeletonCOMMUNICATIONS BIOLOGY. Bd. 5. H. 1. 2022
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Inflammatory Monocyte Counts Determine Venous Blood Clot Formation and ResolutionARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. Bd. 42. H. 2. 2022 S. 145-155
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K(2P)18.1 translates T cell receptor signals into thymic regulatory T cell developmentCELL RESEARCH. Bd. 32. H. 1. 2022 S. 72-88
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Mast cells partly contribute to allergic enteritis development: Findings in two different mast cell-deficient miceALLERGY. Bd. 77. H. 3. 2022 S. 1051-1054
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Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKC delta for tumorigenesisMOLECULAR CANCER. Bd. 21. H. 1. 2022
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pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophagesPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 119. H. 12. 2022
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Systemically Administered TLR7/8 Agonist and Antigen-Conjugated Nanogels Govern Immune Responses against TumorsACS NANO. Bd. 16. H. 3. 2022 S. 4426-4443
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The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functionsCELL DEATH & DISEASE. Bd. 13. H. 4. 2022
Czysch, Christian; Medina-Montano, Carolina; Zhong, Zifu et al.
Transient Lymph Node Immune Activation by Hydrolysable Polycarbonate NanogelsADVANCED FUNCTIONAL MATERIALS. 2022
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A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitisSCIENCE. Bd. 371. H. 6525. 2021 S. 146-+
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Adaptive Mechanisms of Somatostatin-Positive Interneurons after Traumatic Brain Injury through a Switch of alpha Subunits in L-Type Voltage-Gated Calcium ChannelsCEREBRAL CORTEX. Bd. 32. H. 5. 2021 S. 1093-1109
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Arming Immune Cells for Battle: A Brief Journey through the Advancements of T and NK Cell ImmunotherapyCANCERS. Bd. 13. H. 6. 2021
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Blastic Plasmacytoid Dendritic Cell Neoplasm: Single Center Experience on a Rare Hematological MalignancyINDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION. Bd. 37. H. 1. 2021 S. 67-75
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CD27 expression on Treg cells limits immune responses against tumorsJOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 100. H. 3. 2021 S. 439-449
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Characterization and Manipulation of the Crosstalk Between Dendritic and Natural Killer Cells Within the Tumor MicroenvironmentFRONTIERS IN IMMUNOLOGY. Bd. 12. 2021
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Characterization of 150 Wheat Cultivars by LC-MS-Based Label-Free Quantitative Proteomics Unravels Possibilities to Design Wheat Better for Baking Quality and Human HealthPLANTS-BASEL. Bd. 10. H. 3. 2021
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Comprehensive Genomic and Transcriptomic Analysis of Three Synchronous Primary Tumours and a Recurrence from a Head and Neck Cancer PatientINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Bd. 22. H. 14. 2021
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CRISPR/Cas9-mediated TGF beta RII disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells in vitroJOURNAL OF TRANSLATIONAL MEDICINE. Bd. 19. H. 1. 2021
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Cross-reactive, natural IgG recognizing L. major promote parasite internalization by dendritic cells and promote protective immunityJOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 100. H. 3. 2021 S. 451-460
Demircik, Filiz; Kostka, Susanna Lopez; Tenzer, Stefan et al.
Cross-reactive, natural IgG recognizing L. major promote parasite internalization by dendritic cells and promote protective immunity (Oct, 10.1007/s00109-021-02137-4, 2021)JOURNAL OF MOLECULAR MEDICINE-JMM. Bd. 100. H. 3. 2021 S. 461-461
Olmedo, Addi Josua Romero; Schulz, Axel R.; Huber, Magdalena et al.
Deep phenotypical characterization of human CD3+CD56+T cells by mass cytometryEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 273-273
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Density of Conjugated Antibody Determines the Extent of Fc Receptor Dependent Capture of Nanoparticles by Liver Sinusoidal Endothelial CellsACS NANO. Bd. 15. H. 9. 2021 S. 15191-15209
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Effect of Core-Crosslinking on Protein Corona Formation on Polymeric MicellesMACROMOLECULAR BIOSCIENCE. Bd. 21. H. 4. 2021
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ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppressionCELL DEATH & DISEASE. Bd. 12. H. 11. 2021
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Evidence of a New MoYpd1p Phosphotransferase Isoform in the Multistep Phosphorelay System of Magnaporthe oryzaeJOURNAL OF FUNGI. Bd. 7. H. 5. 2021
Jung, Sascha; Fuchs, Natalie; Johe, Patrick et al.
Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo StudiesJOURNAL OF MEDICINAL CHEMISTRY. Bd. 64. H. 16. 2021 S. 12322-12358
Ohl, Kim; Subramanyam, Sudheendra Hebbar; Look, Thomas et al.
Foxp3-specific deletion of CREB generates Th2 biased ST-2 positive regulatory T-cells with enhanced IL-10 production and suppressive capacityEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 60-60
Price, Leah S.; Adamow, Matthew; Attig, Sebastian et al.
Gating Harmonization Guidelines for Intracellular Cytokine Staining Validated in Second International Multiconsortia Proficiency Panel Conducted by Cancer Immunotherapy Consortium (CIC/CRI)CYTOMETRY PART A. Bd. 99. H. 1. 2021 S. 107-116
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Genetic architecture underlying the expression of eight alpha-amylase trypsin inhibitorsTHEORETICAL AND APPLIED GENETICS. Bd. 134. H. 10. 2021 S. 3427-3441
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GPR65 is a critical mediator of low pH induced immunosuppressive signalling in tumor associated macrophages: Human target validation of GPR65 as a novel innate immune checkpoint and discovery of potent, selective GPR65 antagonists.CANCER RESEARCH. Bd. 81. H. 13. 2021
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. H. 12. 2021 S. 2708-3145
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Hybrid QconCAT-Based Targeted Absolute and Data-Independent Acquisition-Based Label-Free Quantification Enables In-Depth Proteomic Characterization of Wheat Amylase/Trypsin Inhibitor ExtractsJOURNAL OF PROTEOME RESEARCH. Bd. 20. H. 3. 2021 S. 1544-1557
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IL-17 controls central nervous system autoimmunity through the intestinal microbiomeSCIENCE IMMUNOLOGY. Bd. 6. H. 56. 2021
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In Activated Murine Mast Cells, NFATc2 Is Critical for the Production of Autocrine IL-3, Thereby Promoting the Expression of IL-9JOURNAL OF IMMUNOLOGY. Bd. 206. H. 1. 2021 S. 67-76
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Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil GranulocytesFRONTIERS IN IMMUNOLOGY. Bd. 11. 2021
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Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivityEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 51-51
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Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivityJOURNAL OF EXPERIMENTAL MEDICINE. Bd. 218. H. 1. 2021
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Limited proteolysis by acrosin affects sperm-binding and mechanical resilience of the mouse zona pellucidaMOLECULAR HUMAN REPRODUCTION. Bd. 27. H. 4. 2021
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Local radiotherapy and E7 RNA-LPX vaccination show enhanced therapeutic efficacy in preclinical models of HPV16(+) cancerCANCER IMMUNOLOGY IMMUNOTHERAPY. Bd. 71. H. 8. 2021 S. 1975-1988
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Mast Cell Deficiency Protects Susceptible BALB/c Mice from Progressive Murine Cutaneous LeishmaniasisJOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 141. H. 2. 2021 S. 450-453
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MaxDIA enables library-based and library-free data-independent acquisition proteomicsNATURE BIOTECHNOLOGY. Bd. 39. H. 12. 2021 S. 1563-+
Luu, Maik; Riester, Zeno; Baldrich, Adrian et al.
Microbial short-chain fatty acids modulate CD8(+) T cell responses and improve adoptive immunotherapy for cancerNATURE COMMUNICATIONS. Bd. 12. H. 1. 2021
Lang, Franziska; Ferreiro, Pablo Riesgo; Loewer, Martin et al.
NeoFox: annotating neoantigen candidates with neoantigen featuresBIOINFORMATICS. Bd. 37. H. 22. 2021 S. 4246-4247
Muhammad, Khalid; Xavier, Delicia; Klein-Hessling, Stefan et al.
NFAT5 Controls the Integrity of EpidermisFRONTIERS IN IMMUNOLOGY. Bd. 12. 2021
Koenig, Anika; Vaeth, Martin; Chiarolla, Cristina Maria et al.
NFATc1/alpha A and Blimp-1 support the follicular and effector phenotype of murine TregsEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 222-222
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OpenTIMS, TimsPy, and TimsR: Open and Easy Access to timsTOF Raw DataJOURNAL OF PROTEOME RESEARCH. Bd. 20. H. 4. 2021 S. 2122-2129
Lordick, Florian; Al-Batran, Salah-Eddin; Ganguli, Arijit et al.
Patient-reported outcomes from the phase II FAST trial of zolbetuximab plus EOX compared to EOX alone as first-line treatment of patients with metastatic CLDN18.2+gastroesophageal adenocarcinomaGASTRIC CANCER. Bd. 24. H. 3. 2021 S. 721-730
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Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zonePROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 118. H. 38. 2021
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Racing for a SARS-CoV-2 vaccineEMBO MOLECULAR MEDICINE. Bd. 13. H. 11. 2021
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Regulation of NADPH Oxidase-Mediated Superoxide Production by Acetylation and DeacetylationFRONTIERS IN PHYSIOLOGY. Bd. 12. 2021
Ring, Sabine; Inaba, Yutaka; Da, Meihong et al.
Regulatory T Cells Prevent Neutrophilic Infiltration of Skin during Contact Hypersensitivity Reactions by Strengthening the Endothelial BarrierJOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 141. H. 8. 2021 S. 2006-2017
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cellsIMMUNITY. Bd. 54. H. 4. 2021 S. 702-+
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Specialized regulatory T cells control venous blood clot resolution through SPARCBLOOD. Bd. 137. H. 11. 2021 S. 1517-1526
Stergiou, Natascha; Urschbach, Moritz; Gabba, Adele et al.
The Development of Vaccines from Synthetic Tumor-Associated Mucin Glycopeptides and their Glycosylation-Dependent Immune ResponseCHEMICAL RECORD. Bd. 21. H. 11. 2021 S. 3313-3331
Formes, Henning; Bernardes, Joana P.; Mann, Amrit et al.
The gut microbiota instructs the hepatic endothelial cell transcriptomeISCIENCE. Bd. 24. H. 10. 2021
Lutz, Veronika; Picard, Felix; Hellmund, Veronique et al.
The role of Interleukin-18 signaling for intratumoral T cell dysfunction in a murine pancreatic cancer modelEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 51. 2021 S. 135-135
Johann, Kerstin; Bohn, Toszka; Shahneh, Fatemeh et al.
Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repressionNATURE COMMUNICATIONS. Bd. 12. H. 1. 2021
Bittel, Miriam; Reichert, Patrick; Sarfati, Ilann et al.
Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivoJOURNAL OF EXTRACELLULAR VESICLES. Bd. 10. H. 12. 2021
Heimes, A. S.; Fries, P.; Stergiou, N. et al.
(TA)MUC1 as a potential new target for breast cancer therapyGEBURTSHILFE UND FRAUENHEILKUNDE. Bd. 80. H. 10. 2020 S. E213-E213
Sadanandam, Anguraj; Bopp, Tobias; Dixit, Santosh et al.
A blood transcriptome-based analysis of disease progression, immune regulation, and symptoms in coronavirus-infected patientsCELL DEATH DISCOVERY. Bd. 6. H. 1. 2020
Salomon, Nadja; Vascotto, Fulvia; Selmi, Abderaouf et al.
A liposomal RNA vaccine inducing neoantigen-specific CD4(+)T cells augments the antitumor activity of local radiotherapy in miceONCOIMMUNOLOGY. Bd. 9. H. 1. 2020
Loquai, Carmen; Hassel, Jessica Cecile; Oehm, Petra et al.
A shared tumor-antigen RNA-lipoplex vaccine with/without anti-PD1 in patients with checkpoint-inhibition experienced melanoma.JOURNAL OF CLINICAL ONCOLOGY. Bd. 38. H. 15. 2020
Beissert, Tim; Perkovic, Mario; Vogel, Annette et al.
A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective ImmunityMOLECULAR THERAPY. Bd. 28. H. 1. 2020 S. 119-128
Lang, Judith; Bohn, Patrick; Bhat, Hilal et al.
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe diseaseNATURE COMMUNICATIONS. Bd. 11. H. 1. 2020
Sahin, Ugur; Oehm, Petra; Derhovanessian, Evelyna et al.
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanomaNATURE. Bd. 585. H. 7823. 2020 S. 107-+
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Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase ACHEMMEDCHEM. 2020
Woelfinger, Pascal; Epp, Katharina; Schaefer, Lukas et al.
CD52-negative T cells predict acute graft-versus-host disease after an alemtuzumab-based conditioning regimenBRITISH JOURNAL OF HAEMATOLOGY. Bd. 191. H. 2. 2020 S. 253-262
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CD52-negative T cells predict acute graft-versus-host disease after an alemtuzumab-based conditioning regimenBRITISH JOURNAL OF HAEMATOLOGY. Bd. 191. H. 2. 2020 S. 253-262
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Characterization of activation induced [(18)]F-FDG uptake in Dendritic CellsNUKLEARMEDIZIN-NUCLEAR MEDICINE. 2020
Eichel, Maria A.; Gargareta, Vasiliki-Ilya; D'Este, Elisa et al.
CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nervesNATURE COMMUNICATIONS. Bd. 11. H. 1. 2020
Bresadola, Luisa; Kong, Anthony; Loewer, Martin et al.
Comprehensive Genomic and Transcriptomic Analysis of Primary and Recurrent Head and Neck CancersONCOLOGY RESEARCH AND TREATMENT. Bd. 43. 2020 S. 230-230
Romero-Olmedo, Addi J.; Schulz, Axel R.; Huber, Magdalena et al.
Deep phenotypical characterization of human CD3(+)CD56(+) T cells by mass cytometryEUROPEAN JOURNAL OF IMMUNOLOGY. 2020
Vormehr, Mathias; Lehar, Sophie; Kranz, Lena M. et al.
Dexamethasone premedication suppresses vaccine-induced immune responses against cancerONCOIMMUNOLOGY. Bd. 9. H. 1. 2020
Bogucka, Katarzyna; Pompaiah, Malvika; Marini, Federico et al.
ERK3/MAPK6 controls IL-8 production and chemotaxisELIFE. Bd. 9. 2020
Turonova, Beata; Sikora, Mateusz; Schuermann, Christoph et al.
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hingesSCIENCE. Bd. 370. H. 6513. 2020 S. 203-+
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Integrative analysis of structural variations using short-reads and linked-reads yields highly specific and sensitive predictionsPLOS COMPUTATIONAL BIOLOGY. Bd. 16. H. 11. 2020
Hauptmann, Judith; Johann, Lisa; Marini, Federico et al.
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrierACTA NEUROPATHOLOGICA. 2020
Uebbing, Lukas; Ziller, Antje; Siewert, Christian et al.
Investigation of pH-Responsiveness inside Lipid Nanoparticles for Parenteral mRNA Application Using Small-Angle X-ray ScatteringLANGMUIR. Bd. 36. H. 44. 2020 S. 13331-13341
Sharma, Arjun; Klein, Matthias; Schuetze, Kristian et al.
MAVS DEFICIENCY CONFERS UNEXPECTED PROTECTION FROM LETHALITY DURING POLYMICROBIAL SEPSISSHOCK. Bd. 53. 2020 S. 30-31
Schaupp, Laura; Muth, Sabine; Rogell, Leif et al.
Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic CellsCELL. Bd. 181. H. 5. 2020 S. 1080-+
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Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancerJOURNAL OF CLINICAL INVESTIGATION. Bd. 130. H. 7. 2020 S. 3560-3575
Mohebiany, Alma Nazlie; Ramphal, Nishada Shakunty; Karram, Khalad et al.
Microglial A20 Protects the Brain from CD8 T-Cell-Mediated ImmunopathologyCELL REPORTS. Bd. 30. H. 5. 2020 S. 1585-+
Schroers, Barbara; Boegel, Sebastian; Albrecht, Christian et al.
Multi-Omics Characterization of the 4T1 Murine Mammary Gland Tumor ModelFRONTIERS IN ONCOLOGY. Bd. 10. 2020
Klein, Philipp; Barthels, Fabian; Johe, Patrick et al.
Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases-Studies on Inhibition Mechanism and KineticsMOLECULES. Bd. 25. H. 9. 2020
Alflen, Astrid; Lopez, Pamela Aranda; Hartmann, Ann-Kathrin et al.
Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosisIMMUNOBIOLOGY. Bd. 225. H. 1. 2020
Klein, Philipp; Johe, Patrick; Wagner, Annika et al.
New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease RhodesainMOLECULES. Bd. 25. H. 6. 2020
Klemm, Patricia; Rajendiran, Anandhi; Fragoulis, Athanassios et al.
Nrf2 expression driven by Foxp3 specific deletion of Keap1 results in loss of immune tolerance in miceEUROPEAN JOURNAL OF IMMUNOLOGY. 2020
Fruehbeis, Carsten; Kuo-Elsner, Wen Ping; Mueller, Christina et al.
Oligodendrocytes support axonal transport and maintenance via exosome secretionPLOS BIOLOGY. Bd. 18. H. 12. 2020
Alberg, Irina; Kramer, Stefan; Schinnerer, Meike et al.
Polymeric Nanoparticles with Neglectable Protein CoronaSMALL. Bd. 16. H. 18. 2020
Nogueira, Sara S.; Schlegel, Anne; Maxeiner, Konrad et al.
Polysarcosine-Functionalized Lipid Nanoparticles for Therapeutic mRNA DeliveryACS APPLIED NANO MATERIALS. Bd. 3. H. 11. 2020 S. 10634-10645
Krishnan, Aswini; Berthelet, Jean; Renaud, Emilie et al.
Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomasNATURE COMMUNICATIONS. Bd. 11. H. 1. 2020
Distler, Ute; Schumann, Sven; Kesseler, Hans-Georg et al.
Proteomic Analysis of Brain Region and Sex-Specific Synaptic Protein Expression in the Adult Mouse BrainCELLS. Bd. 9. H. 2. 2020
Riegel, Kristina; Schloeder, Janine; Sobczak, Marco et al.
RAF kinases are stabilized and required for dendritic cell differentiation and functionCELL DEATH AND DIFFERENTIATION. Bd. 27. H. 4. 2020 S. 1300-1315
Wolf, Christina; del Amo, Victor Lopez; Arndt, Sabine et al.
Redox Modifications of Proteins of the Mitochondrial Fusion and Fission MachineryCELLS. Bd. 9. H. 4. 2020