Formyl peptide receptors from the innate immune system and the vomeronasal organ recognize pathogen derived peptides
Journal of Neuroimmunology. Bd. 275. H. 1-2. Elsevier BV 2014 S. 91 - 92
Erscheinungsjahr: 2014
ISBN/ISSN: 1872-8421
Publikationstyp: Zeitschriftenaufsatz
Sprache: Englisch
Doi/URN: 10.1016/j.jneuroim.2014.08.245
Geprüft | Bibliothek |
Inhaltszusammenfassung
The formyl peptide receptor (Fpr) family is well known for its contribution to immune defense against pathogens in human and rodent leukocytes. Recently, several structurally related members of these receptors were discovered in sensory neurons of the mouse vomeronasal organ (VNO), key detectors of pheromones and related semiochemicals. Although the biological role of vomeronasal Fprs is not yet clear, the known contribution of other Fprs to host innate immune defense suggested that they coul...The formyl peptide receptor (Fpr) family is well known for its contribution to immune defense against pathogens in human and rodent leukocytes. Recently, several structurally related members of these receptors were discovered in sensory neurons of the mouse vomeronasal organ (VNO), key detectors of pheromones and related semiochemicals. Although the biological role of vomeronasal Fprs is not yet clear, the known contribution of other Fprs to host innate immune defense suggested that they could contribute to vomeronasal pathogen sensing.» weiterlesen» einklappen
Autoren
Klassifikation
DFG Fachgebiet:
Neurowissenschaften
DDC Sachgruppe:
Biowissenschaften, Biologie