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A phase I/II study of immunotherapy for patients with metastatic melanoma using dendritic cells transfected with plasmid encoding two melanoma antigens

Laufzeit: 01.01.2004 - 31.12.2006


To create a safe and effective therapeutic cancer vaccine, potential antigens including bacterial antigens are investigated systematically as vaccine variables.
Whilst several cancer vaccines are in late-stage clinical development, very few are used in clinical practice. The currently approved vaccines are comprised of tumor cell-derived components that contain uncharacterized mixtures of potentially immunogenic and immunosuppressive components.

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