Professor Dr. Dr. Oliver Müller
Fachbereich Informatik und Mikrosystemtechnik, Hochschule Kaiserslautern
- 0631/3724-5427
- 0631/3724-5305
Müller, Oliver; Gourzoulidou, Eleni; Carpintero, Mercedes et al.
Identification of Potent Ras Signaling Inhibitors by Pathway-Selective Phenotype-Based ScreeningAngewandte Chemie International Edition. Bd. 43. H. 4. Wiley 2004 S. 450 - 454
Karaguni, Ioanna-Maria; Gourzoulidou, Eleni; Carpintero, Mercedes et al.
SMAF-1 Inhibits the APC/β-Catenin Pathway and Shows Properties Similar to Those of the Tumor Suppressor Protein APCChemBioChem. Bd. 5. H. 9. Wiley 2004 S. 1267 - 1270
Waldmann, Herbert; Karaguni, Ioanna-Maria; Carpintero, Mercedes et al.
Sulindac-Derived Ras Pathway Inhibitors Target the Ras–Raf Interaction and Downstream Effectors in the Ras PathwayAngewandte Chemie International Edition. Bd. 43. H. 4. Wiley 2004 S. 454 - 458
Oliveira, M. J.; van Damme, J.; Lauwaet, T. et al.
Beta -casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motilityThe EMBO Journal. Bd. 22. H. 22. Wiley 2003 S. 6161 - 6173
Tickenbrock, Lara; Kößmeier, Katja; Rehmann, Holger et al.
Differences Between the Interaction of β-Catenin with Non-phosphorylated and Single-mimicked Phosphorylated 20-amino acid Residue Repeats of the APC ProteinJournal of Molecular Biology. Bd. 327. H. 2. Elsevier B.V. 2003 S. 359 - 367
Müller, Oliver; Chtarbova, S.
Eine Frage zu Krebs? Die Antwort weiß nur der Wnt Signalweg.BIOspektrum. 9(6). Aufl. unbekannt. 2003 S. 701 - 703
Müller, Oliver
Identification of Colon Cancer Patients by Molecular DiagnosisDigestive Diseases. Bd. 21. H. 4. S. Karger AG 2003 S. 315 - 319
Thutewohl, Michael; Kissau, Lars; Popkirova, Boriana et al.
Identification of mono- and bisubstrate inhibitors of protein farnesyltransferase and inducers of apoptosis from a pepticinnamin E libraryBioorganic & Medicinal Chemistry. Bd. 11. H. 12. Elsevier B.V. 2003 S. 2617 - 2626
Ebert, Matthias P.A.; Yu, Jun; Hoffmann, Juliane et al.
Loss of Beta-Catenin Expression in Metastatic Gastric CancerJournal of Clinical Oncology. Bd. 21. H. 9. American Society of Clinical Oncology (ASCO) 2003 S. 1708 - 1714
Andreyev, H J N; Benamouzig, R.; Beranek, M. et al.
Mutant K-ras2 in serumGut. Bd. 52. H. 6. BMJ 2003 S. 915 - 916
Müller, Oliver; Rosenbaum, C.; Baumhof, P. et al.
Synthesis and biological evaluation of an Indomethacin library reveals a new class of angiogenesis-related kinase inhibitorsAngewandte Chemie. Bd. 43. H. 2. 2003 S. 224 - 228
Kahmann, Sabine; Herter, Peter; Kuhnen, Cornelius et al.
A non-radioactive protein truncation test for the sensitive detection of all stop and frameshift mutationsHuman Mutation. Bd. 19. H. 2. Wiley 2002 S. 165 - 172
Debruyne, P. R.; Bruyneel, E. A.; Karaguni, I-M. et al.
Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathwaysOncogene. Bd. 21. H. 44. Springer Science and Business Media LLC 2002 S. 6740 - 6750
Ebert, M. P.A.; Fei, G.; Kahmann, S. et al.
Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancerCarcinogenesis. Bd. 23. H. 1. Oxford University Press (OUP) 2002 S. 87 - 91
Chtarbova, Slava; Nimmrich, Inko; Erdmann, Silke et al.
Murine Nr4a1 and Herpud1 are up-regulated by Wnt-1, but the homologous human genes are independent from β-catenin activationBiochemical Journal. Bd. 367. H. 3. Portland Press Ltd. 2002 S. 723 - 728
Müller, Oliver; Brohm, D.; Metzger, S. et al.
Natural Products Are Biologically Validated Starting Points in Structural Space for Compound Library Development: Solid‐Phase Synthesis of Dysidiolide‐Derived Phosphatase InhibitorsAngewandte Chemie. Bd. 114. 2002 S. 319 - 323
Karaguni, Ioanna-Maria; Glüsenkamp, Karl-Heinz; Langerak, Anette et al.
New indene-derivatives with anti-proliferative propertiesBioorganic & Medicinal Chemistry Letters. Bd. 12. H. 4. Elsevier BV 2002 S. 709 - 713
Müller, Oliver; Wittinghofer, A.
Ras binding compoundsAcademic Press New York (Hrsg). Tumor Suppressing Viruses, Genes, and Drugs. unbekannt. 2002 S. 311 - 327 (Chapter 15)
Müller, Oliver; Thutewohl, M.; Kissau, LA. et al.
Solid-phase synthesis and biological evaluation of a Pepticinnamine E library.Angewandte Chemie. Bd. 114. 2002 S. 3768 - 3772
Brohm, Dirk; Philippe, Nicolas; Metzger, Susanne et al.
Solid-Phase Synthesis of Dysidiolide-Derived Protein Phosphatase InhibitorsJournal of the American Chemical Society. Bd. 124. H. 44. American Chemical Society (ACS) 2002 S. 13171 - 13178
Tickenbrock, Lara; Cramer, Janina; Vetter, Ingrid et al.
Structure of the Amino-Terminal Nuclear Export Domain of the APC Tumor Suppressor ProteinAnnals of the New York Academy of Sciences. Bd. 973. H. 1. Wiley 2002 S. 109 - 111
Tickenbrock, Lara; Cramer, Janina; Vetter, Ingrid R. et al.
The Coiled Coil Region (Amino Acids 129–250) of the Tumor Suppressor Protein Adenomatous Polyposis Coli (APC)Journal of Biological Chemistry. Bd. 277. H. 35. Elsevier B.V. 2002 S. 32332 - 32338
Müller, Oliver; Karaguni, IM; Herter, P. et al.
The new Sulindac derivative IND 12 reverses Ras-induced cell transformation.Cancer Research. Bd. 62. 2002 S. 1718 - 1723
Müller, Oliver
Die Analyse von DNA aus fäkalen Proben als Grundlage einer nicht invasiven molekularen Diagnose gastrointestinaler Tumoren Fortschritt und Fortbildung in der MedizinBundesärztekammer (Hrsg). Band 25. Aufl. Köln: Deutscher Ärzte-Verlag 2001 S. 151 - 157
Müller, Oliver
Die Analyse von DNA aus fäkalen Proben als Grundlage einer nicht invasiven molekularen Diagnose gastrointestinaler TumorenBundesärztekammer (Hrsg). Bd. 25. Köln: Deutscher Ärzte-Verlag 2001 S. 151 - 157 (Fortschritt und Fortbildung in der Medizin)
Leroy, K.; Duyckaerts, C.; Bovekamp, L. et al.
Increase of adenomatous polyposis coli immunoreactivity is a marker of reactive astrocytes in Alzheimer's disease and in other pathological conditionsActa Neuropathologica. Bd. 102. Springer Science and Business Media LLC 2001 S. 1 - 10
Müller, O.; Andreyev, HJ; Norman, AR et al.
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' studyBritish Journal of Cancer. Bd. 85. H. 8. 2001 S. 692 - 696
Böse, Guido; Kuhlmann, Jürgen; Plass, Martina et al.
Microplate Enzyme-Linked Immunosorbent Assay for the Detection of Primary DNA Alterations Based on the Interaction with UvrA/UvrBAnalytical Biochemistry. Bd. 292. H. 1. Elsevier BV 2001 S. 1 - 7
Nimmrich, Inko; Erdmann, Silke; Melchers, Ute et al.
The novel ependymin related gene UCC1 is highly expressed in colorectal tumor cellsCancer Letters. Bd. 165. H. 1. Elsevier B.V. 2001 S. 71 - 79
Kuhnen, Cornelius; Herter, Peter; Monse, Hella et al.
APC and β-catenin in alveolar soft part sarcoma (ASPS) - immunohistochemical and molecular genetic analysisPathology - Research and Practice. Bd. 196. H. 5. Elsevier BV 2000 S. 299 - 304
Nimmrich, Inko; Erdmann, Silke; Melchers, Ute et al.
Seven genes that are differentially transcribed in colorectal tumor cell linesCancer Letters. Bd. 160. H. 1. Elsevier B.V. 2000 S. 37 - 43
Erdmann, Kai S.; Kuhlmann, Jürgen; Lessmann, Volkmar et al.
The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domainOncogene. Bd. 19. H. 34. Springer Science and Business Media LLC 2000 S. 3894 - 3901
Kuhnen, Cornelius; Herter, Peter; Müller, Oliver et al.
β-Catenin in Soft tissue Sarcomas: Expression is Related to Proliferative Activity in High-Grade SarcomasModern Pathology. Bd. 13. H. 9. Springer Science and Business Media LLC 2000 S. 1005 - 1013
Herter, Peter; Kuhnen, Cornelius; Müller, Klaus-Michael et al.
Intracellular distribution of β-catenin in colorectal adenomas, carcinomas and Peutz-Jeghers polypsJournal of Cancer Research and Clinical Oncology. Bd. 125. H. 5. Springer Science and Business Media LLC 1999 S. 297 - 304
Müller, Oliver
Methoden zur Isolierung und zur Analyse von DNA aus fäkalen Proben als Grundlage einer nicht-invasiven molekulargenetischen Tumor- und InfektionsdiagnostikJahrbuch des Wissenschaftszentrums Nordrhein-Westfalen. Düsseldorf. 1999 S. 127 - 139
Müller, Oliver
Methoden zur Isolierung und zur Analyse von DNA aus fäkalen Proben als Grundlage einer nicht-invasiven molekulargenetischen Tumor- und Infektionsdiagnostik.Jahrbuch des Wissenschaftszentrums Nordrhein-Westfalen. unbekannt. 1999 S. 127 - 139
Deka, Jürgen; Herter, Peter; Sprenger-Haußels, Markus et al.
The APC protein binds to A/T rich DNA sequencesOncogene. Bd. 18. H. 41. Springer Science and Business Media LLC 1999 S. 5654 - 5661
Müller, Oliver; Nimmrich, I; Finke, U. et al.
A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patientsGenes Chromosomes and Cancer. Bd. 22. 1998 S. 37 - 41
Deka, Jurgen; Kuhlmann, Jurgen; Muller, Oliver
A domain within the tumor suppressor protein APC shows very similar biochemical properties as the microtubule-associated protein tauEuropean Journal of Biochemistry. Bd. 253. H. 3. Wiley 1998 S. 591 - 597
Winde, Guenther; Lügering, Norbert; Glodny, Bernhard et al.
Decreased HER-2 tyrosine kinase expression in rectal mucosa of FAP patients following low-dose sulindac chemopreventionCancer Letters. Bd. 134. H. 2. Elsevier B.V. 1998 S. 201 - 207
Müller, Oliver; Deuter, R.
Detection of APC mutations in stool DNA of patients with colorectal cancer by HD‐PCRHuman Mutation. Bd. 11. 1998 S. 84 - 89
Müller, Oliver; Kuhnen, C.; Herter, P. et al.
Intracellular distribution of beta-catenin in soft tissue tumorsVerhandlungen der deutschen Gesellschaft für Pathologie. Bd. 82. 1998 S. 322 - 326
Jenne, Dieter E.; Reomann, Heike; Nezu, Jun-ichi et al.
Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinaseNature Genetics. Bd. 18. H. 1. Springer Science and Business Media LLC 1998 S. 38 - 43
Herrmann, Christian; Block, Christoph; Geisen, Christoph et al.
Sulindac sulfide inhibits Ras signalingOncogene. Bd. 17. H. 14. Springer Science and Business Media LLC 1998 S. 1769 - 1776
Winde, Guenther; Schmid, Kurt W.; Brandt, Burkhardt et al.
Clinical and genomic influence of sulindac on rectal mucosa in familial adenomatous polyposisDiseases of the Colon & Rectum. Bd. 40. H. 10. Ovid Technologies (Wolters Kluwer Health) 1997 S. 1156 - 1169
Müller, Oliver; Böse, G.; Deka, J. et al.
Die Krebsentstehung auf molekularer EbeneJahrbuch der Max-Planck-Gesellschaft. Göttingen. 1997 S. 286 - 290
Müller, Oliver; Böse, G.; Deka, J. et al.
Jahrbuch der Max-Planck-Gesellschaft. Die Krebsentstehung auf molekularer Ebeneunbekannt. 1997 S. 286 - 290
Nimmrich, Inko; Friedl, Waltraut; Kruse, Roland et al.
Loss of the PLA2G2A gene in a sporadic colorectal tumor of a patient with a PLA2G2A germline mutation and absence of PLA2G2A germline alterations in patients with FAPHuman Genetics. Bd. 100. H. 3-4. Springer Science and Business Media LLC 1997 S. 345 - 349
Deuter, Rainer; Linz, Jochen; Pietsch, Stephan et al.
DNA alterations in sporadic colorectal tumors do not correlate with tumor staging diagnosed by the TNM systemCancer Letters. Bd. 109. H. 1-2. Elsevier B.V. 1996 S. 161 - 169
Hirschl, Daniela; Bayer, Peter; Müller, Oliver
Secondary structure of an armadillo single repeat from the APC proteinFEBS Letters. Bd. 383. H. 1-2. Wiley 1996 S. 31 - 36