Univ.-Prof. Dr. rer. nat. Hartmut Lüddens
FB 04 - Universitätsmedizin, Johannes Gutenberg-Universität Mainz
- 06131/17-5372
- 06131/17-5590
Sinkkonen, Saku T.; Lüscher, Bernhard; Lüddens, Hartmut et al.
Autoradiographic imaging of altered synaptic abg2 and extrasynaptic ab GABAA receptors in a genetic mouse model of anxietyNeurochemistry international. the internat. journal for the rapid publ. of critical reviews, preliminary and original research communications in neurochemistry. Bd. 44. H. 7. Amsterdam: Elsevier 2004 S. 539 - 548
Fellgiebel, Andreas; Siessmeier, Thomas; Winterer, Georg et al.
Increased cerebellar pet glucose metabolism corresponds to ataxia in wernicke-korsakoff syndromeAlcohol and alcoholism. the international journal of the Medical Council on Alcoholism and the journal of the European Society for Biomedical Research on Alcoholism. Bd. 39. H. 2. Oxford: Univ. Press 2004
Böhme, Ingo; Rabe, Holger; Lüddens, Hartmut
MECHANISMS OF SIGNAL TRANSDUCTION - Four Amino Acids in the a Subunits Determine the g-Aminobutyric Acid Sensitivities of GABAA Receptor Subtypes.The journal of biological chemistry. JBC. Bd. 279. H. 34. Bethesda, Md.: ASBMB 2004 S. 35193 - 35200
Koksma, Jan-Jurjen; Kesteren, Ronald E.van; Rosahl, Thomas W. et al.
CELLULAR-MOLECULAR - Oxytocin Regulates Neurosteroid Modulation of GABAA Receptors in Supraoptic Nucleus around ParturitionThe journal of neuroscience. the official journal of the Society for Neuroscience. Bd. 23. H. 3. Washington, DC: Society for Neuroscience 2003 S. 788 - 797
Sinkkonen, Saku T.; Mansikkamäki, Salla; Möykkynen, Tommi et al.
Receptor Subtype-Dependent Positive and Negative Modulation of GABAA Receptor Function by Niflumic Acid, a Nonsteroidal Anti-Inflammatory DrugMolecular pharmacology. an international journal. Bd. 64. H. 3. Bethesda, Md.: American Society for Pharmacology and Experimental Therapeutics 2003 S. 753 - 763
Piel, Markus; Schirrmacher, Ralf; Höhnemann, Sabine et al.
Synthesis and evaluation of 5,7-dichloro-4-(3-{4-(4-(2-(18F)fluoroethyl)-piperazin-1-yl)-phenyl- }-ureido)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid as a potential NMDA ligand to study glutamatergic neurotransmission in vivoJournal of labelled compounds & radiopharmaceuticals. Bd. 46. H. 7. London: Wiley 2003 S. 645 - 660
Korpi, E.R.; Mihalek, R.M.; Sinkkonen, S.T. et al.
Altered receptor subtypes in the forebrain of GABAA receptor d subunit-deficient mice: recruitment of g2 subunitsNeuroscience. Bd. 109. H. 4. Oxford: Elsevier 2002 S. 733 - 744
Schmitt, U.; Lüddens, H.; Hiemke, C.
Anxiolytic-like effects of acute and chronic GABA transporter inhibition in ratsJournal of neural transmission. JNT. Bd. 109. H. 5. Wien [u.a.]: Springer 2002 S. 871 - 880
Korpi, E. R.; Gründer, G.; Lüddens, H.
Drug Interactions in GABA-A ReceptorsProgress in Neurobiology. Bd. Progress in Neurobiology. 2002 S. 113-159
Davids, Eugen; Hevers, Wulf; Dämgen, Kerstin et al.
Organotypic rat cerebellar slice culture as a model to analyze the molecular pharmacology of GABAA receptorsEuropean neuropsychopharmacology. ENP ; the journal of the European College of Neuropsychopharmacology. Bd. 12. H. 3. Amsterdam: Elsevier 2002 S. 201 - 208
Hevers, W.; Lüddens, H.
Pharmacological heterogeneity of g-aminobutyric acid receptors during development suggests distinct classes of rat cerebellar granule cells in situNeuropharmacology. Bd. 42. H. 1. Orlando, Fla. [u.a.]: Elsevier 2002 S. 34 - 47
Gründer, Gerhard; Siessmeier, Thomas; Lange-Asschenfeldt, Christian et al.
(18F)Fluoroethylflumazenil: a novel tracer for PET imaging of human benzodiazepine receptorsEuropean journal of nuclear medicine and molecular imaging. official organ of the European Association of Nuclear Medicine (EANM). Bd. 28. H. 10. Berlin: Springer 2001 S. 1463 - 1470
Sinkkonen, Saku T.; Mihalek, Robert M.; Homanics, Gregg E. et al.
Altered atypical coupling of g-aminobutyrate type A receptor agonist and convulsant binding sites in subunit-deficient mouse linesBrain research. Bd. 86. H. 1. Amsterdam [u.a.]: Elsevier 2001 S. 179 - 183
Sinkkonen, Saku T.; Uusi-Oukari, Mikko; Tupala, Erkki et al.
Characterization of g-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regionsBrain research. Bd. 86. H. 1. Amsterdam [u.a.]: Elsevier 2001 S. 168 - 178
Schmitt, U.; Lüddens, H.; Hiemke, C.
FULL LENGTH ORIGINAL PAPERS - EXPERIMENTAL LABORATORY STUDIES - Behavioral analysis indicates benzodiazepine-tolerance mediated by the benzodiazepine binding-site at the GABAA-receptorProgress in neuro-psychopharmacology & biological psychiatry. Bd. 25. H. 5. Oxford: Pergamon Press 2001 S. 1145 - 1160
Möykkynen, Tommi; Uusi-Oukari, Mikko; Heikkilä, Jari et al.
NEUROCHEMISTRY - Magnesium potentiation of the function of native and recombinant GABAA receptorsNeuroreport. an international journal for the rapid communication of research in neuroscience. Bd. 12. H. 10. London: Lippincott Williams & Wilkins 2001 S. 2175 - 2180
Schirrmacher, R.; Hamkens, W.; Piel, M. et al.
Radiosynthesis of ((plus-minus))-(2-((4-(2-(18F) fluoro-ethoxy)phenyl)bis(4-methoxy-phenyl)methoxy) ethylpiperidine-3-carboxylic acid: A potential GAT-3 PET ligand to study GABAergic neuro-transmission in vivoJournal of labelled compounds & radiopharmaceuticals. Bd. 44. H. 9. London: Wiley 2001 S. 627 - 642
Böhme, Ingo; Lüddens, Hartmut
The Inhibitory Neural Circuitry as Target of Antiepileptic DrugsCurrent medicinal chemistry. the new international journal for timely in-depth reviews in medicinal chemistry. Bd. 8. H. 11. Schiphol: Bentham 2001 S. 1257 - 1274