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Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

NATURE REVIEWS NEUROSCIENCE. Bd. 12. H. 9. 2011 S. 524 - 538

Erscheinungsjahr: 2011

ISBN/ISSN: 1471-003X

Publikationstyp: Zeitschriftenaufsatz

Doi/URN: 10.1038/nrn3044

Volltext über DOI/URN

Geprüft:Bibliothek

Inhaltszusammenfassung


The neuropeptides oxytocin (OXT) and arginine vasopressin (AVP) are evolutionarily highly conserved mediators in the regulation of complex social cognition and behaviour. Recent studies have investigated the effects of OXT and AVP on human social interaction, the genetic mechanisms of inter-individual variation in social neuropeptide signalling and the actions of OXT and AVP in the human brain as revealed by neuroimaging. These data have advanced our understanding of the mechanisms by which t...The neuropeptides oxytocin (OXT) and arginine vasopressin (AVP) are evolutionarily highly conserved mediators in the regulation of complex social cognition and behaviour. Recent studies have investigated the effects of OXT and AVP on human social interaction, the genetic mechanisms of inter-individual variation in social neuropeptide signalling and the actions of OXT and AVP in the human brain as revealed by neuroimaging. These data have advanced our understanding of the mechanisms by which these neuropeptides contribute to human social behaviour. OXT and AVP are emerging as targets for novel treatment approaches-particularly in synergistic combination with psychotherapy-for mental disorders characterized by social dysfunction, such as autism, social anxiety disorder, borderline personality disorder and schizophrenia. » weiterlesen» einklappen

Autoren


Meyer-Lindenberg, Andreas (Autor)
Kirsch, Peter (Autor)
Heinrichs, Markus (Autor)

Verknüpfte Personen


Gregor Domes

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