Reversible activation of pH-sensitive cell penetrating peptides attached to gold surfaces
Chemical Communications. Bd. 51. 2015 S. 273 - 275
Erscheinungsjahr: 2015
ISBN/ISSN: 0009-241X
Publikationstyp: Zeitschriftenaufsatz
Sprache: Englisch
Doi/URN: 10.1039/C4CC07278B
| Geprüft | Bibliothek |
Inhaltszusammenfassung
pH-sensitive viral fusion protein mimics are widely touted as a promising route towards site-specific delivery of therapeutic compounds across lipid membranes. Here, we demonstrate that a fusion protein mimic, designed to achieve a reversible, pH-driven helix-coil transition mechanism, retains its functionality when covalently bound to a surface.
Autoren
Baio, Joe E (Autor)
Schach, Denise (Autor)
Fuchs, Adrian (Autor)
Schmüser, Lars (Autor)
Billecke, Nils (Autor)
Bubeck, Christoph (Autor)
Landfester, Katharina (Autor)
Bonn, Mischa (Autor)
Bruns, Michael (Autor)
Weidner, Tobias (Autor)
Klassifikation
DDC Sachgruppe:
Chemie
