Univ.-Prof. Dr. med. Christoph Huber - Publikationen

Bobek, N.; Kuball, J.; Thaler, S. et al.
Inhibitors of apoptosis confer resistance to tumour suppression by adoptively transplanted cytotoxic T-lymphocytes in vitro and in vivo
Cell death and differentiation. D & D ; cdd. Bd. 12. H. 4. London: Arnold 2005 S. 317 - 325

Kindler, T.; Breitenbuecher, F.; Kasper, S. et al.
NEOPLASIA - Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML)
Washington, DC: American Society of Hematology 2005 S. 335 - 340

Schuler, Martin; Green, Douglas R.; Huber, Christoph
Transcription, apoptosis and p53: catch-22
Amsterdam: Elsevier 2005 S. 182 - 187

Kindler, T.; Breitenbuecher, F.; Marx, A. et al.
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS - Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia
Washington, DC: American Society of Hematology 2004 S. 3644 - 3654

Chipuk, J.E.; Kuwana, T.; Bouchier-Hayes, L. et al.
REPORTS - CELL BIOLOGY: Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis - In addition to its well-known role as a transcription factor, the p53 tumor suppressor promotes cell death by activating a cytoplasmic
Washington, DC: American Assoc. for the Advancement of Science 2004 S. 1010 - 1013

Scott, C.L.; Schuler, M.; Marsden, V.S. et al.
Research Articles - Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation
New York, NY: Rockefeller Univ. Press 2004 S. 89 - 96

Schinzel, A.; Kaufmann, T.; Schuler, M. et al.
Research Articles - Conformational control of Bax localization and apoptotic activity by Pro 168
New York, NY: Rockefeller Univ. Press 2004 S. 1021 - 1032

Hasenjäger, Anne; Gillissen, Bernhard; Müller, Antje et al.
Smac induces cytochrome c release and apoptosis independently from Bax-Bcl-xL in a strictly caspase-3-dependent manner in human carcinoma cells
Basingstoke: Nature Publ. Group 2004 S. 4523 - 4535

Dörrschuck, A.; Schmidt, A.; Schnürer, E. et al.
TRANSPLANTATION - CD8+ cytotoxic T lymphocytes isolated from allogeneic healthy donors recognize HLA class Ia-Ib-associated renal carcinoma antigens with ubiquitous or restricted tissue expression
Washington, DC: American Society of Hematology 2004 S. 2591 - 2599

Kindler, T.; Breitenbuecher, F.; Marx, A. et al.
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS - Brief report Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML
Blood. the journal of hematology. Bd. 101. H. 8. Washington, DC: American Society of Hematology 2003 S. 2960 - 2962

Kindler, T.; Breitenbuecher, F.; Kasper, S. et al.
In BCR-ABL-positive cells, STAT-5 tyrosine-phosphorylation integrates signals induced by imatinib mesylate and Ara-C
Leukemia. the journal of normal and malignant hemopoiese ; official journal of the Leukemia Research Fund U.K. Bd. 17. H. 6. Basingstoke: Nature Publ. Group 2003 S. 999 - 1009

Schuler, M.; Maurer, U.; Goldstein, J.C. et al.
p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation
London: Arnold 2003 S. 451 - 460

Huber, Christoph; Chipuk, J. E.; Maurer, U. et al.
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
Cancer Cell. Bd. Cancer Cell. 2003 S. 371-381

Milosevic, Javorina; Hoffarth, Sandra; Huber, Claudia et al.
The DNA damage-induced decrease of Bcl-2 is secondary to the activation of apoptotic effector caspases
Oncogene. an international journal. Bd. 22. H. 44. Basingstoke: Nature Publ. Group 2003 S. 6852 - 6856

Huber, Christoph; Guilhot, F.; Larson, R. et al.
The IRIS Study: International Randomized study of Interferon and low-dose Ara-C versus STI571 (imatinib) in patients with newly-diagnosed chronic phase chronic myeloid leukemia
New England Journal of Medicine. Bd. New England Journal of Medicine. 2003 S. 994-1004

Huber, Christoph; Kantarjian, C. L.; Sawyers, A. et al.
Hematologic and Cytogenetic Responses to Imatinib Mesylate in Chronic Myelogenous Leukemia
New England Journal of Medicine. Bd. New England Journal of Medicine. 2002 S. 645-652

Hartwig, U.F.; Robbers, M.; Wickenhauser, C. et al.
TRANSPLANTATION - Murine acute graft-versus-host disease can be prevented by depletion of alloreactive T lymphocytes using activation-induced cell death
Blood. the journal of hematology. Bd. 99. H. 8. Washington, DC: American Society of Hematology 2002 S. 3041 - 3049

Britten, Cedrik M.; Meyer, Ralf G.; Kreer, Tanja et al.
The use of HLA-A*0201-transfected K562 as standard antigen-presenting cells for CD8+ T lymphocytes in IFN-g ELISPOT assays
Amsterdam [u.a.]: Elsevier 2001 S. 95 - 110

Seliger, Barbara; Hohne, Alexandra; Knuth, Alexander et al.
Analysis of the Major Histocompatibility Complex Class I Antigen Presentation Machinery in Normal and Malignant Renal Cells: Evidence for Deficiencies Associated with Transformation and Progression
Cancer research. an official organ of the American Association for Cancer Research. Bd. 56. H. 8. Birmingham, Ala. [u.a.]: AACR 1996 S. 1756 - 1760

Albrecht, T.; Schwab, R.; Peschel, C. et al.
Cationic lipide mediated transfer of c-abl and bcr antisense oligonucleotides to immature normal myeloid cells: Uptake, biological effects and modulation of gene expression
Annals of hematology. organ of Deutsche Gesellschaft für Hämatologie und Onkologie, Gesellschaft für Thrombose- und Hämostaseforschung, Österreichische Gesellschaft für Hämatologie und Onkologie. Bd. 72. H. 2. Berlin: Springer 1996 S. 73 - 80

Nachbaur, D.; Niederwieser, D.; Aichinger, G. et al.
CD4 monoclonal antibody VIT4 in human alloimune response in vitro and in vivo
Immunobiol. Bd. Immunobiol. 1996 S. 33-46

Thews, Oliver; Thews, Anne; Huber, Christoph et al.
Computer-Assisted Interpretation of Flow Cytometry Data in Hematology
Cytometry. the journal of the International Society for Analytical Cytology. Bd. 23. H. 2. New York, NY [u.a.]: Wiley-Liss 1996 S. 140 - 149

Decker, H.-J.H.; Neuhaus, C.; Jauch, A. et al.
Detection of a germline mutation and somatic homozygous loss of the von Hippel-Lindau tumor-suppressor gene in a family with a de novo mutation. A combined genetic study, including cytogenetics, PCR-SSCP, FISH, and CGH
Human genetics &lt;Berlin&gt;. Bd. 97. H. 6. Berlin: Springer 1996 S. 770 - 776

Fischer, Thomas; Aman, Javad; Kuip, Heiko van der et al.
Induction of interferon regulatory factors, 2'-5' oligoadenylate synthetase, P69 kinase and RNase L in chronic myelogenous leukaemia cells and its relationship to clinical responsiveness
British journal of haematology. BJH ; the official journal of the British Society of Haematology. Bd. 92. H. 3. Oxford [u.a.]: Blackwell 1996 S. 595 - 603

Thaler, J.; Gastl, G.; Fluckinger, T. et al.
Interferon alpha-2c therapy of patients with chronic myelogenous leukemia: Long-term results of a multi-center phase-II study
Annals of hematology. organ of Deutsche Gesellschaft für Hämatologie und Onkologie, Gesellschaft für Thrombose- und Hämostaseforschung, Österreichische Gesellschaft für Hämatologie und Onkologie. Bd. 72. H. 6. Berlin: Springer 1996 S. 349 - 356

Aman, M.J.; Tretter, T.; Eisenbeis, I. et al.
Interferon-a Stimulates Production of Interleukin-10 in Activated CD4+ T Cells and Monocytes
Blood. the journal of hematology. Bd. 87. H. 11. Washington, DC: American Society of Hematology 1996 S. 4731 - 4736

Lohmann, S.; Wollscheid, U.; Huber, C. et al.
Multiple Levels of MHC Class I Down-Regulation by ras Oncogenes
Scandinavian journal of immunology. the official journal of the Scandinavian Society for Immunology. Bd. 43. H. 5. Oxford [u.a.]: Blackwell 1996 S. 537 - 544

Haque, S.Jaharul; Kuip, Heiko van der; Kumar, Aseem et al.
Overexpression of Mouse p140 Subunit of Replication Factor C Accelerates Cellular Proliferation
Cell growth & differentiation. CG&D ; the molecular biology journal of the American Association for Cancer Research. Bd. 7. H. 3. Baltimore, Md.: Waverly Press 1996 S. 319 - 326

Seliger, Barbara; Höhne, Alexandra; Knuth, Alexander et al.
Reduced Membrane Major Histocompatibility Complex Class I Density and Stability in a Subset of Human Renal Cell Carcinomas with Low TAP and LMP Expression
Clinical cancer research. an official journal of the American Association for Cancer Research. Bd. 2. H. 8. Philadelphia, Pa. [u.a.]: AACR 1996 S. 1427 - 1434

Stöckle, M.; Meyenburg, W.; Wellek, S. et al.
Adjuvant Polychemotherapy of Nonorgan-Confined Bladder Cancer After Radical Cystectomy Revisited: Long-Term Results of Controlled Prospective Study and Further Clinical Experience
The journal of urology. official organ of the American Urological Association. Bd. 153. H. 1. Baltimore, Md.: Lippincott Williams & Wilkins 1995 S. 47 - 52

Aulitzky, W.E.; Peschel, C.; Schneller, F. et al.
Biotherapy of chronic myelogenous leukemia
Annals of hematology. organ of Deutsche Gesellschaft für Hämatologie und Onkologie, Gesellschaft für Thrombose- und Hämostaseforschung, Österreichische Gesellschaft für Hämatologie und Onkologie. Bd. 70. H. 3. Berlin: Springer 1995 S. 113 - 120

Schuler, M.; Huber, C.; Peschel, C.
Cytokines in the pathophysiology and treatment of chronic B-cell malignancies
Annals of hematology. organ of Deutsche Gesellschaft für Hämatologie und Onkologie, Gesellschaft für Thrombose- und Hämostaseforschung, Österreichische Gesellschaft für Hämatologie und Onkologie. Bd. 71. H. 2. Berlin: Springer 1995 S. 57 - 64

Schwab, R.; Peschel, C.; Despés, D. et al.
Deficient cell cycle control in myeloid cells of patients with newly diagnosted chronic myeloid leukemia
Cytok. Molec. Therapy. Bd. Cytok. Molec. Therapy. 1995 S. 281-288

Després, D.; Goldschmitt, J.; Aulitzky, W.E. et al.
Differential effect of type I interferons on hematopoietic progenitor cells: Failure of interferons to inhibit IL-3-stimulated normal and CML myeloid progenitors
Experimental hematology. official publication of the International Society for Experimental Hematology. Bd. 23. H. 14. Kidlington [u.a]: Elsevier 1995 S. 1431 - 1438

Geissler, Klaus; Peschel, Christian; Niederwieser, Dietger et al.
Effect of interleukin-3 pretreatment on granulocyte-macrophage colony-stimulating factor induced mobilization of circulating haemopoietic progenitor cells
British journal of haematology. BJH ; the official journal of the British Society of Haematology. Bd. 91. H. 2. Oxford [u.a.]: Blackwell 1995 S. 299 - 305

Eibl, B.; Greiter, E.; Grünewald, K. et al.
Expression of c-fos correlates with IFN-* responsiveness in Philadelphia chromosome positive chronic myelogenous leukemia
J. Cytok. Molec. Therapy. Bd. J. Cytok. Molec. Therapy. 1995 S. 29-38

Heil, G.; Chadid, L.; Hoelzer, D. et al.
GM-CSF in a Double-Blind Randomized, Placebo Controlled Trial in Therapy of Adult Patients with De Novo Acute Myeloid Leukemia (AML)
Leukemia. the journal of normal and malignant hemopoiese ; official journal of the Leukemia Research Fund U.K. Bd. 9. H. 1. Basingstoke: Nature Publ. Group 1995 S. 3 - 9

Göllner, Gerhard; Aman, M.Javad; Steffens, Hans Peter et al.
Interferon-a (IFN-a) inhibits granulocyte-macrophage colony-stimulating factor (GM-CSF) expression at the post-transcriptional level in murine bone marrow stromal cells
British journal of haematology. BJH ; the official journal of the British Society of Haematology. Bd. 91. H. 1. Oxford [u.a.]: Blackwell 1995 S. 8 - 14

Aulitzky, W.; Ellerhorst, J.; Logothetis, C. et al.
Intermittent Low-Dose IFN Gamma Treatment for Metastatic Renal Cell Carcinoma: Analysis of Factors Predicting Clinical Response and Long-Term Survival
Onkologie. international journal for cancer research and treatment. Bd. 18. H. 4. Basel: Karger 1995 S. 339 - 345

Schönborn, H.; Schuler, M.; Kolbe, K. et al.
Plasma levels of IL-1, TNF alpha, IL-6, IL-8, G-CSF, and IL1-RA during febrile neutropenia: Results of a prospective study in patients undergoing chemotherapy for acute myelogenous leukemia
Annals of hematology. organ of Deutsche Gesellschaft für Hämatologie und Onkologie, Gesellschaft für Thrombose- und Hämostaseforschung, Österreichische Gesellschaft für Hämatologie und Onkologie. Bd. 71. H. 4. Berlin: Springer 1995 S. 161 - 168

Decker, T.; Flohr, T.; Trautmann, P. et al.
Role of Accessory Cells in Cytokine Production by T Cells in Chronic B-Cell Lymphocytic Leukemia
Blood. the journal of hematology. Bd. 86. H. 3. Washington, DC: American Society of Hematology 1995 S. 1115 - 1123

Aulitzky, W. E.; Peschel, C.; Schneller, F. et al.
The merits of action of interferon * in chronic myelogenous leukemia
Forum. Bd. Forum. 1995 S. 328-338