Forschungszentrum für Immuntherapie (FZI)
Forschungsschwerpunkt / Johannes Gutenberg-Universität Mainz
Sonnemann, Juergen; Grauel, Desiree; Bluemel, Lisa et al.
RETRA exerts anticancer activity in Ewing's sarcoma cells independent of their TP53 statusEUROPEAN JOURNAL OF CANCER. Bd. 51. H. 7. 2015 S. 841-851
Reuter, Eva; Weber, Juliane; Paterka, Magdalena et al.
Role of Sortilin in Models of Autoimmune NeuroinflammationJOURNAL OF IMMUNOLOGY. Bd. 195. H. 12. 2015 S. 5762-5769
Tian, Na; Messana, Irene; Leffler, Daniel A. et al.
Salivary proline-rich proteins and gluten: Do structural similarities suggest a role in celiac disease?PROTEOMICS CLINICAL APPLICATIONS. Bd. 9. H. 9-10. 2015 S. 953-964
Susewind, Moritz; Schilmann, Anna-Maria; Heim, Julia et al.
Silica-coated Au@ZnO Janus particles and their stability in epithelial cellsJournal of materials chemistry : B. Bd. 3. H. 9. Cambridge: The Royal Society of Chemistry 2015 S. 1813 - 1822
Elentner, Andreas; Ortner, Daniela; Clausen, Bjoern E. et al.
Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptorEXPERIMENTAL DERMATOLOGY. Bd. 24. H. 11. 2015 S. 835-840
Pencik, Jan; Schlederer, Michaela; Gruber, Wolfgang et al.
STAT3 regulated ARF expression suppresses prostate cancer metastasisNATURE COMMUNICATIONS. Bd. 6. 2015
Pencik, Jan; Schlederer, Michaela; Gruber, Wolfgang et al.
STAT3 regulated ARF expression suppresses prostate cancer metastasis (vol 6, 7736, 2015)NATURE COMMUNICATIONS. Bd. 6. 2015
Torok, Natalie J.; Dranoff, Jonathan A.; Schuppan, Detlef et al.
Strategies and endpoints of antifibrotic drug trials: Summary and recommendations from the AASLD Emerging Trends Conference, Chicago, June 2014HEPATOLOGY. Bd. 62. H. 2. 2015 S. 627-634
Drube, Sebastian; Weber, Franziska; Loschinski, Romy et al.
Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cellsONCOTARGET. Bd. 6. H. 7. 2015 S. 5354-5368
Dankowski, Theresa; Buck, Dorothea; Andlauer, Till F. M. et al.
Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome ArrayGENETIC EPIDEMIOLOGY. Bd. 39. H. 8. 2015 S. 601-608
Wagner, Tobias; Kiweler, Nicole; Wolff, Katharina et al.
Sumoylation of HDAC2 promotes NF-kappa B-dependent gene expressionONCOTARGET. Bd. 6. H. 9. 2015 S. 7123-7135
Wagner, T.; Kraemer, O. H.; Heinzel, T.
Sumoylation of histone deacetylase 2 regulates tumor relevant gene expression patternsFEBS JOURNAL. Bd. 282. 2015 S. 88-88
Clausen, Bjoern E.; Brand, Anna; Karram, Khalad
Surmounting limited gene delivery into primary immune cell populations: Efficient cell type-specific adenoviral transduction by CAREUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 45. H. 6. 2015 S. 1596-1599
Oeser, K.; Maxeiner, J.; Symowski, C. et al.
T cells are the critical source of IL-4/IL-13 in a mouse model of allergic asthmaALLERGY. Bd. 70. H. 11. 2015 S. 1440-1449
Voisinne, Guillaume; Nixon, Briana G.; Melbinger, Anna et al.
T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar AntigensCELL REPORTS. Bd. 11. H. 8. 2015 S. 1208-1219
Gerlach, Katharina; Hwang, YouYi; Nikolaev, Alexej et al.
T(H)9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells (vol 15, pg 676, 2014)NATURE IMMUNOLOGY. Bd. 16. H. 2. 2015
Kang, Biao; Okwieka, Patricia; Schoettler, Susanne et al.
Tailoring the stealth properties of biocompatible polysaccharide nanocontainersBIOMATERIALS. Bd. 49. 2015 S. 125-134
Drube, Sebastian; Weber, Franziska; Goepfert, Christiane et al.
TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseasesONCOTARGET. Bd. 6. H. 30. 2015 S. 28833-28850
Weng, Shih-Yen; Vijayan, Santosh; Wang, Xiaoyu et al.
The antifibrotic effect of IL-4R alpha signaling depends on macrophage subsets prevalent during liver fibrosis progression and reversalHEPATOLOGY. Bd. 62. 2015 S. 301A-302A
Tomaszowski, Karl-Heinz; Aasland, Dorthe; Margison, Geoffrey P. et al.
The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicityDNA REPAIR. Bd. 28. 2015 S. 14-20
Deng, Shiwei; Yan, Tiandong; Nikolova, Teodora et al.
The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cellsBRITISH JOURNAL OF PHARMACOLOGY. Bd. 172. H. 9. 2015 S. 2246-2257
Reissig, Sonja; Hoevelmeyer, Nadine; Tang, Yilang et al.
The deubiquitinating enzyme CYLD regulates the differentiation and maturation of thymic medullary epithelial cellsIMMUNOLOGY AND CELL BIOLOGY. Bd. 93. H. 6. 2015 S. 558-566
Doersam, B.; Wu, C. -F; Efferth, T. et al.
The Eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damageNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 388. 2015 S. S68-S68
Doersam, Bastian; Wu, Ching-Fen; Efferth, Thomas et al.
The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damageARCHIVES OF TOXICOLOGY. Bd. 89. H. 5. 2015 S. 797-805
Knauer, Shirley K.; Mahendrarajah, Nisintha; Roos, Wynand P. et al.
The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancersCYTOKINE & GROWTH FACTOR REVIEWS. Bd. 26. H. 4. 2015 S. 405-413
Maus, Frank; Sakry, Dominik; Binamé, Fabien et al.
The NG2 proteoglycan protects oligodendrocyte precursor cells against oxidative stress via interaction with OMI/HtrA2PLoS one. Bd. 10. H. 9. Lawrence, Kan.: PLoS 2015 e0137311
Mohebiany, A.; Waisman, A.
The role and impact of A20 expression by microglia in neuroinflammationGLIA. Bd. 63. 2015 S. E344-E344
Waisman, Ari; Hauptmann, Judith; Regen, Tommy
The role of IL-17 in CNS diseasesACTA NEUROPATHOLOGICA. Bd. 129. H. 5. 2015 S. 625-637
Waisman, Ari; Regen, Tommy; Mufazalov, Ilgiz et al.
The role of IL-17 in CNS diseasesCYTOKINE. Bd. 76. H. 1. 2015 S. 64-64
Kitic, M.; Karram, K.; Israel, N. et al.
The role of NG2 in inflammatory disease of the CNSGLIA. Bd. 63. 2015 S. E336-E336
Dufner, Almut; Kisser, Agnes; Niendorf, Sandra et al.
The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cellsNature immunology. Bd. 16. H. 9. New York, NY: Nature America Inc. 2015 S. 950 - 960
Thomas, Adam D.; Fahrer, Joerg; Johnson, George E. et al.
Theoretical considerations for thresholds in chemical carcinogenesisMUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. Bd. 765. 2015 S. 56-67
Klein, Matthias; Bruehl, Till-Julius; Staudt, Valerie et al.
Tick Salivary Sialostatin L Represses the Initiation of Immune Responses by Targeting IRF4-Dependent Transcription in Murine Mast CellsJOURNAL OF IMMUNOLOGY. Bd. 195. H. 2. 2015 S. 621-631
Gasteiger, Georg; Fan, Xiying; Dikiy, Stanislav et al.
Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organsScience. Bd. 350. H. 6263. Washington, DC: American Association for the Advancement of Science 2015 S. 981 - 985
Diefenbach, Andreas
Transcriptional control of innate lymphoid cell fate decisionsCYTOKINE. Bd. 76. H. 1. 2015 S. 62-62
Bodor, Josef; Bohn, Tozska; Bopp, Tobias et al.
Transcriptional regulation of cytokines in regulatory T cell-mediated suppression and its role in antitumor therapyCYTOKINE. Bd. 76. H. 1. 2015 S. 106-106
He, Shuqing; Krippes, Kristina; Ritz, Sandra et al.
Ultralow-intensity near-infrared light induces drug delivery by upconverting nanoparticlesCHEMICAL COMMUNICATIONS. Bd. 51. H. 2. 2015 S. 431-434
Schuppan, Detlef; Zevallos, Victor
Wheat Amylase Trypsin Inhibitors as Nutritional Activators of Innate ImmunityDIGESTIVE DISEASES. Bd. 33. H. 2. 2015 S. 260-263
Muth, Sabine; Schuetze, Kristian; Hain, Tobias et al.
A CD40/CD40L feedback loop drives the breakdown of CD8(+) T-cell tolerance following depletion of suppressive CD4(+) T cellsEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 44. H. 4. 2014 S. 1099-1107
Schwarz, Alexandra; Tenzer, Stefan; Hackenberg, Michael et al.
A Systems Level Analysis Reveals Transcriptomic and Proteomic Complexity in Ixodes Ricinus Midgut and Salivary Glands During Early Attachment and FeedingMOLECULAR & CELLULAR PROTEOMICS. Bd. 13. H. 10. 2014 S. 2725-2735
Malzahn, Kerstin; Jamieson, William D.; Droege, Melanie et al.
Advanced dextran based nanogels for fighting Staphylococcus aureus infections by sustained zinc releaseJOURNAL OF MATERIALS CHEMISTRY B. Bd. 2. H. 15. 2014 S. 2175-2183
Loos, Cornelia; Syrovets, Tatiana; Musyanovych, Anna et al.
Amino-functionalized nanoparticles as inhibitors of mTOR and inducers of cell cycle arrest in leukemia cellsBIOMATERIALS. Bd. 35. H. 6. 2014 S. 1944-1953
Distler, Ute; Kuharev, Joerg; Tenzer, Stefan
Biomedical applications of ion mobility-enhanced data-independent acquisition-based label-free quantitative proteomicsEXPERT REVIEW OF PROTEOMICS. Bd. 11. H. 6. 2014 S. 675-684
Toprak, Umut H.; Gillet, Ludovic C.; Maiolica, Alessio et al.
Conserved Peptide Fragmentation as a Benchmarking Tool for Mass Spectrometers and a Discriminating Feature for Targeted ProteomicsMOLECULAR & CELLULAR PROTEOMICS. Bd. 13. H. 8. 2014 S. 2056-2071
Mooz, Juliane; Oberoi-Khanuja, Tripat Kaur; Harms, Gregory S. et al.
Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migrationSCIENCE SIGNALING. Bd. 7. H. 337. 2014
Liebl, Martina P.; Kaya, Ali M.; Tenzer, Stefan et al.
Dimerization of visinin-like protein 1 is regulated by oxidative stress and calcium and is a pathological hallmark of amyotrophic lateral sclerosisFREE RADICAL BIOLOGY AND MEDICINE. Bd. 72. 2014 S. 41-54
Weber, Michael; Stein, Pamela; Pruefer, Steve et al.
Donor and host B cell-derived IL-10 contributes to suppression of graft-versus-host diseaseEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 44. H. 6. 2014 S. 1857-1865
Distler, Ute; Kuharev, Jörg; Navarro, Pedro et al.
Drift time-specific collision energies enable deep-coverage data-independent acquisition proteomicsNature methods. Bd. 11. H. 2. New York, NY: Nature Publishing Group 2014 S. 167 - 170
Hofmann, Daniel; Messerschmidt, Claudia; Bannwarth, Markus B. et al.
Drug delivery without nanoparticle uptake: delivery by a kiss-and-run mechanism on the cell membraneCHEMICAL COMMUNICATIONS. Bd. 50. H. 11. 2014 S. 1369-1371
Claus, H.; Tenzer, S.; Sobe, M. et al.
Effect of carboxymethyl cellulose on tartrate salt, protein and colour stability of red wineAUSTRALIAN JOURNAL OF GRAPE AND WINE RESEARCH. Bd. 20. H. 2. 2014 S. 186-193
Stein, Pamela; Gogoll, Karsten; Tenzer, Stefan et al.
Efficacy of imiquimod-based transcutaneous immunization using a nano-dispersed emulsion gel formulationPLoS one. Bd. 9. H. 7. Lawrence, Kan.: PLoS 2014 e102664
Siebeneicher, S.; Reuter, S.; Krause, M. et al.
Epicutaneous immune modulation with Bet v 1 plus R848 suppresses allergic asthma in a murine modelALLERGY. Bd. 69. H. 3. 2014 S. 328-337
Tenzer, Stefan; Crawford, Hayley; Pymm, Phillip et al.
HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype DiversificationCELL REPORTS. Bd. 7. H. 2. 2014 S. 448-463
Weber, Michael; Rudolph, Berenice; Stein, Pamela et al.
Host-Derived CD8(+) Dendritic Cells Protect Against Acute Graft-versus-Host Disease after Experimental Allogeneic Bone Marrow TransplantationBIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. Bd. 20. H. 11. 2014 S. 1696-1704
Barthel, Anne-Kathrin; Dass, Martin; Droege, Melanie et al.
Imaging the intracellular degradation of biodegradable polymer nanoparticlesBEILSTEIN JOURNAL OF NANOTECHNOLOGY. Bd. 5. 2014 S. 1905-1917
Distler, Ute; Schmeisser, Michael J.; Pelosi, Assunta et al.
In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomicsPROTEOMICS. Bd. 14. H. 21-22. 2014 S. 2607-2613
Schick, Isabel; Lorenz, Steffen; Gehrig, Dominik et al.
Inorganic Janus particles for biomedical applicationsBEILSTEIN JOURNAL OF NANOTECHNOLOGY. Bd. 5. 2014 S. 2346-2362
Weilbaecher, Martin; Allmeroth, Mareli; Hemmelmann, Mirjam et al.
Interaction of N-(2-Hydroxypropyl)Methacrylamide Based Homo, Random and Block Copolymers with Primary Immune CellsJOURNAL OF BIOMEDICAL NANOTECHNOLOGY. Bd. 10. H. 1. 2014 S. 81-91
Karbach, Susanne; Croxford, Andrew L.; Oelze, Matthias et al.
Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin diseaseArteriosclerosis, thrombosis, and vascular biology. Bd. 34. H. 12. Hagerstown, Md.: Lippincott, Williams & Wikins 2014 S. 2658 - 2668
Best, Christoph; Lange, Elena; Buchholz, Hans-Georg et al.
Left hemispheric dominance of vestibular processing indicates lateralization of cortical functions in ratsBRAIN STRUCTURE & FUNCTION. Bd. 219. H. 6. 2014 S. 2141-2158
Hofmann, Daniel; Tenzer, Stefan; Bannwarth, Markus B. et al.
Mass Spectrometry and Imaging Analysis of Nanoparticle-Containing Vesicles Provide a Mechanistic Insight into Cellular TraffickingACS NANO. Bd. 8. H. 10. 2014 S. 10077-10088
Ebert, Stefan; Becker, Marc; Lemmermann, Niels et al.
Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungsPLoS pathogens. Bd. 10. H. 4. Lawrence, Kan.: PLoS 2014 e1004100
Fruehbeis, C.; Froehlich, D.; Kuo, W. P. et al.
Neurotransmitter signaling regulates exosome secretion from oligodendrocytesACTA PHYSIOLOGICA. Bd. 210. 2014 S. 66-68
Niedbala, Wanda; Besnard, Anne-Gaelle; Nascimento, Daniele Carvalho et al.
Nitric oxide enhances Th9 cell differentiation and airway inflammationNATURE COMMUNICATIONS. Bd. 5. 2014
Stein, J.; Maxeiner, J. H.; Montermann, E. et al.
Non-eosinophilic Airway Hyper-reactivity in Mice, Induced by IFN-gamma Producing CD4(+) and CD8(+) Lung T cells, is Responsive to Steroid TreatmentSCANDINAVIAN JOURNAL OF IMMUNOLOGY. Bd. 80. H. 5. 2014 S. 327-338
Fink, Annette; Büttner, Julia K.; Thomas, Doris et al.
Noncanonical expression of a murine cytomegalovirus early protein CD8 T-cell epitope as an immediate early epitope based on transcription from an upstream geneViruses. Bd. 6. H. 2. Basel: MDPI 2014 S. 808 - 831
Roest, Hannes L.; Rosenberger, George; Navarro, Pedro et al.
OpenSWATH enables automated, targeted analysis of data-independent acquisition MS dataNATURE BIOTECHNOLOGY. Bd. 32. H. 3. 2014 S. 219-223
Tomcin, Stephanie; Baier, Grit; Landfester, Katharina et al.
Pharmacokinetics on a microscale: visualizing Cy5-labeled oligonucleotide release from poly(n- butylcyanoacrylate) nanocapsules in cellsINTERNATIONAL JOURNAL OF NANOMEDICINE. Bd. 9. 2014 S. 5471-5489
Reyda, Sabine; Buescher, Nicole; Tenzer, Stefan et al.
Proteomic Analyses of Human Cytomegalovirus Strain AD169 Derivatives Reveal Highly Conserved Patterns of Viral and Cellular Proteins in Infected FibroblastsVIRUSES-BASEL. Bd. 6. H. 1. 2014 S. 172-188
Docter, Dominic; Distler, Ute; Storck, Wiebke et al.
Quantitative profiling of the protein coronas that form around nanoparticlesNATURE PROTOCOLS. Bd. 9. H. 9. 2014 S. 2030-2044
Probst, Hans Christian; Muth, Sabine; Schild, Hansjoerg
Regulation of the tolerogenic function of steady-state DCsEUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 44. H. 4. 2014 S. 927-933
Nuhn, Lutz; Tomcin, Stephanie; Miyata, Kanjiro et al.
Size-Dependent Knockdown Potential of siRNA-Loaded Cationic Nanohydrogel ParticlesBIOMACROMOLECULES. Bd. 15. H. 11. 2014 S. 4111-4121
Baier, G; Baki, A; Tomcin, S et al.
Stabilization of nanoparticles synthesized by miniemulsion polymerization using "green" amino-acid based surfactantsMacromolecular Symposia. Bd. 337. H. 1. 2014 S. 9-17
Bannwarth, Markus B.; Ebert, Sandro; Lauck, Maximilian et al.
Tailor-Made Nanocontainers for Combined Magnetic-Field-Induced Release and MRIMACROMOLECULAR BIOSCIENCE. Bd. 14. H. 9. 2014 S. 1205-1214
Schmitt, Edgar; Klein, Matthias; Bopp, Tobias
Th9 cells, new players in adaptive immunityTRENDS IN IMMUNOLOGY. Bd. 35. H. 2. 2014 S. 61-68
Reyda, Sabine; Tenzer, Stefan; Navarro, Pedro et al.
The Tegument Protein pp65 of Human Cytomegalovirus Acts as an Optional Scaffold Protein That Optimizes Protein Uploading into Viral ParticlesJOURNAL OF VIROLOGY. Bd. 88. H. 17. 2014 S. 9633-9646