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Institut für Molekulare Medizin

Klinikum / Johannes Gutenberg-Universität Mainz

Publikationen
Ergebnisse pro Seite:  100

Urbanik, Toni; Boger, Regina Johanna; Longerich, Thomas et al.

Liver specific deletion of CYLDexon7/8 induces severe biliary damage, fibrosis and increases hepatocarcinogenesis in mice

JOURNAL OF HEPATOLOGY. Bd. 57. H. 5. 2012 S. 995-1003


Kossmann, S; Knorr, M; Stratmann, J et al.

Lysozyme M positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction

VASCULAR PHARMACOLOGY. Bd. 56. H. 5-6. 2012 S. 317-317


Dudeck, A; Dudeck, J; Scholten, J et al.

Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens

EXPERIMENTAL DERMATOLOGY. Bd. 21. H. 3. 2012 S. e34-e34


Locatelli, G; Wortge, S; Buch, T et al.

Primary oligodendrocyte death does not elicit anti-CNS immunity

NATURE NEUROSCIENCE. Bd. 15. H. 4. 2012 S. 543-550


Cervantes-Barragan, L; Firner, S; Bechmann, I et al.

Regulatory T Cells Selectively Preserve Immune Privilege of Self-Antigens during Viral Central Nervous System Infection

JOURNAL OF IMMUNOLOGY. Bd. 188. H. 8. 2012 S. 3678-3685


Bruttger, J; Wortge, S; Jung, S et al.

Role and function of microglia cells in autoimmune CNS inflammation

IMMUNOLOGY. Bd. 137. 2012 S. 231-232


Gil-Cruz, C; Perez-Shibayama, C; Firner, S et al.

T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Bd. 109. H. 4. 2012 S. 1233-1238


Buch, T; Sledzinska, A; Mair, F et al.

TGF-beta signaling in CD4(+) T cells is essential for their homeostasis but not for self-tolerance

IMMUNOLOGY. Bd. 137. 2012 S. 41-41


Gao, B; Waisman, A

Th17 Cells Regulate Liver Fibrosis by Targeting Multiple Cell Types: Many Birds With One Stone

GASTROENTEROLOGY. Bd. 143. H. 3. 2012 S. 536-539


Fu, QL; Gremeaux, L; Luque, RM et al.

The Adult Pituitary Shows Stem/Progenitor Cell Activation in Response to Injury and Is Capable of Regeneration

ENDOCRINOLOGY. Bd. 153. H. 7. 2012 S. 3224-3235


Berberich-Siebelt, F.; Vaeth, M.; Schliesser, U. et al.

The dependence on NFAT levels discriminates conventional T cells from Foxp3(+) regulatory T cells

IMMUNOLOGY. Bd. 137. 2012 S. 416-416


Reichhold, C; Tirosh, B; Waisman, A

The in vivo role of Blimp-1 SUMOylation in B Cell Development

IMMUNOLOGY. Bd. 137. 2012 S. 340-340


Wanke, F.; Mueller, W.; Waisman, A. et al.

The protective role of interferon gamma in EAE, is not due to effects on dendritic cells

IMMUNOLOGY. Bd. 137. 2012 S. 487-487


Hahn, M; Schluter, D; Nikolaev, A et al.

The role of the deubiquitinating enzymes CYLD and A20 in B-cell maintenance and maturation

IMMUNOLOGY. Bd. 137. 2012 S. 341-342



Reissig, S; Hovelmeyer, N; Weigmann, B et al.

The Tumor Suppressor CYLD Controls the Function of Murine Regulatory T Cells

JOURNAL OF IMMUNOLOGY. Bd. 189. H. 10. 2012 S. 4770-4776


Reissig, S; Hoevelmeyer, N; Kalt, B et al.

The tumor suppressor gene CYLD controls the function of regulatory T cells

IMMUNOLOGY. Bd. 137. 2012 S. 417-418


Mellanby, Richard J.; Cambrook, Helen; Turner, Darryl G. et al.

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

JOURNAL OF NEUROINFLAMMATION. Bd. 9. 2012


Waisman, A

To Be 17 Again - Anti-Interleukin-17 Treatment for Psoriasis

NEW ENGLAND JOURNAL OF MEDICINE. Bd. 366. H. 13. 2012 S. 1251-1252


Gerlach, K; Daniel, C; Lehr, HA et al.

Transcription Factor NFATc2 Controls the Emergence of Colon Cancer Associated with IL-6-Dependent Colitis

CANCER RESEARCH. Bd. 72. H. 17. 2012 S. 4340-4350


Karbach, S; Croxford, A; Oelze, M et al.

Vascular dysfunction and skin inflammation are mechanistically interconnected by IL17A and IL-6 signaling in a mouse model of psoriasis

EUROPEAN HEART JOURNAL. Bd. 33. 2012 S. 277-277


Movadai, O; Wlodarski, A; Neurath, MF et al.

A Novel Mouse Model of Metastatic Colon Cancer Established by Endoscopic Injection of Human Colon Cancer Cells

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S682-S682


Hovelmeyer, N; Reissig, S; Nguyen, TX et al.

A20 deficiency in B cells enhances B-cell proliferation and results in the development of autoantibodies

EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 41. H. 3. 2011 S. 595-601


Atreya, R; Zimmer, M; Bartsch, B et al.

Anti-TNF Antibodies Target T-Cell Apoptosis in Inflammatory Bowel Diseases via the mTNF/TNFR2 Signalling Pathway

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S838-S838


Schattenberg, JM; Woerns, MA; Zimmermann, T et al.

BCL-3 AMELIORATES CD95-INDUCED ACUTE LIVER INJURY IN-VIVO

HEPATOLOGY. Bd. 54. 2011 S. 512A-512A


Knorr, M; Wenzel, P; Kossmann, S et al.

CIRCULATING AND INFILTRATING MONOCYTIC CELLS MEDIATE ANGIOTENSIN-II INDUCED ARTERIAL HYPERTENSION

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Bd. 57. H. 14. 2011 S. E1561-E1561


Kroeger, I; Meinhardt, K; Abendroth, A et al.

Clinical, endoscopic and molecular characterization of murine GvHD colitis

BONE MARROW TRANSPLANTATION. Bd. 46. 2011 S. S243-S243


Waldner, MJ; Wirtz, S; Neufert, C et al.

Confocal laser endomicroscopy and narrow-band imaging-aided endoscopy for in vivo imaging of colitis and colon cancer in mice

NATURE PROTOCOLS. Bd. 6. H. 9. 2011 S. 1471-1481


Weigmann, B; Atreya, R; Lehr, HA et al.

Cyclosporine a Induces Mucosal Cell Apoptosis in Ulcerative Colitis Through the Modulation of the Tee Kinase Itk

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S839-S839


Urbanik, T; Kohler, BC; Boger, RJ et al.

Down-regulation of CYLD as a trigger for NF-kappa B activation and a mechanism of apoptotic resistance in hepatocellular carcinoma cells

INTERNATIONAL JOURNAL OF ONCOLOGY. Bd. 38. H. 1. 2011 S. 121-131


Neumann, H; Vieth, M; Atreya, R et al.

First description of eosinophilic esophagitis using confocal laser endomicroscopy (with video)

ENDOSCOPY. Bd. 43. 2011 S. E66-E66



Leppkes, M; Hirth, S; Croxford, AL et al.

IL-17 Links Autoimmune Pancreatitis to Inflammatory Bowel Disease

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S127-S127


Billmeier, U; Neurath, MF; Wirtz, SJ

IL-23 is a Key Pathogenic Inducer of Chronic Intestinal Inflammation

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S836-S836


Domhoff, H; Doyle, S; Neurath, MF et al.

IL28Ralpha Deficiency Enforces T Cell-Dependent Experimental Colitis via Suppression of Regulatory T-Cells

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S150-S150



Engel, MA; Izydorczyk, I; Mueller-Tribbensee, SM et al.

Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin

NEUROPEPTIDES. Bd. 45. H. 3. 2011 S. 229-237


Wenzel, Philip; Knorr, Maike; Kossmann, Sabine et al.

Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction

Circulation. Bd. 124. H. 12. Baltimore, MD: Lippincott Williams & Wilkins 2011 S. 1370 - 1381


Lucas, T; Waisman, A; Krieg, T et al.

Macrophages as sentinels directing the quality of skin repair

EXPERIMENTAL DERMATOLOGY. Bd. 20. H. 2. 2011 S. 204-204


Waisman, A

MECHANISMS OF OLIGODENDROCYTE DEATH IN ANIMAL MODELS OF MS

GLIA. Bd. 59. 2011 S. S11-S11



Kurschus, FC; Wortge, S; Waisman, A

Modeling a Complex Disease: Multiple Sclerosis

Advances in Immunology. Bd. 110. 2011 S. 111-137


Croxford, AL; Kurschus, FC; Waisman, A

Mouse models for multiple sclerosis: Historical facts and future implications

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. Bd. 1812. H. 2. 2011 S. 177-183


Wortge, S; Locatelli, G; Buch, T et al.

PRIMARY OLIGODENDROCYTE DEATH DOES NOT ELICIT ANTI-CNS IMMUNITY

GLIA. Bd. 59. 2011 S. S154-S154


Neumann, H; Vieth, M; Atreya, R et al.

Prospective evaluation of the learning curve of confocal laser endomicroscopy in patients with IBD

HISTOLOGY AND HISTOPATHOLOGY. Bd. 26. H. 7. 2011 S. 867-872





Bruttger, J; Waisman, A

ROLE AND FUNCTION OF MICROGLIA CELLS IN AUTOIMMUNE CNS INFLAMMATION

GLIA. Bd. 59. 2011 S. S72-S72


Engel, MA; Becker, C; Reeh, PW et al.

Role of Sensory Neurons in Colitis: Increasing Evidence for a Neuroimmune Link in the Gut

INFLAMMATORY BOWEL DISEASES. Bd. 17. H. 4. 2011 S. 1030-1033


Wittkopf, N; Billmeier, U; Gunther, C et al.

STAT3-Mediated Production of Antimicrobial Peptides by Intestinal Epithelial Cells Helps Controlling C. rodentium Induced Infection

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S325-S325


Waisman, A

T helper cell populations: As flexible as the skin?

EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 41. H. 9. 2011 S. 2539-2543



Cervantes-Barragan, L; Firner, S; Shibayama, CP et al.

Unmutated immunoglobulin M efficiently protects against virus-induced demyelinating disease

ALLERGOLOGIE. Bd. 34. H. 2. 2011 S. 83-83


Waldner, MJ; Wirtz, SJ; Jefremow, A et al.

VEGFR2 Signaling in Intestinal Epithelial Cells Drives Development of Colitis-Associated Colon Cancer

GASTROENTEROLOGY. Bd. 140. H. 5. 2011 S. S351-S351


Okuyama, M; Kayama, H; Atarashi, K et al.

A novel in vivo inducible dendritic cell ablation model in mice

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. Bd. 397. H. 3. 2010 S. 559-563



Neufert, C; Pickert, G; Zheng, Y et al.

Activation of epithelial STAT3 regulates intestinal homeostasis

CELL CYCLE. Bd. 9. H. 4. 2010 S. 652-655


Neurath, MF; Wittkopf, N; Wlodarski, A et al.

Assessment of Tumor Development and Wound Healing Using Endoscopic Techniques in Mice

GASTROENTEROLOGY. Bd. 139. H. 6. 2010 S. 1837-U93


Frommer, F; Waisman, A

B Cells Participate in Thymic Negative Selection of Murine Auto-reactive CD4(+) T Cells

PLOS ONE. Bd. 5. H. 10. 2010 S. -



Wirtz, S; Nagel, G; Eshkind, L et al.

Both base excision repair and O-6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis

CARCINOGENESIS. Bd. 31. H. 12. 2010 S. 2111-2117


Atreya, R; Neurath, MF

Chemokines in Inflammatory Bowel Diseases

DIGESTIVE DISEASES. Bd. 28. H. 3. 2010 S. 386-394


Chalaris, A; Adam, N; Sina, C et al.

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

JOURNAL OF EXPERIMENTAL MEDICINE. Bd. 207. H. 8. 2010 S. 1617-1624


Urbanik, T; Heine, S; Worns, M et al.

CYLD: A KEY REGULATOR OF HEPATOCELLULAR APOPTOSIS, PROLIFERATION AND CARCINOGENESIS

JOURNAL OF HEPATOLOGY. Bd. 52. 2010 S. S32-S33


Kurschus, FC; Jenne, DE

Delivery and therapeutic potential of human granzyme B

IMMUNOLOGICAL REVIEWS. Bd. 235. 2010 S. 159-171


Nir, Y; Friederike, F; Dominika, L et al.

Dendritic cells control tolerance in EAE via the induction of Tregs by the PD-1 signalling pathway

JOURNAL OF NEUROIMMUNOLOGY. Bd. 228. H. 1-2. 2010 S. 114-115


Lucas, T; Waisman, A; Ranjan, R et al.

Differential Roles of Macrophages in Diverse Phases of Skin Repair

JOURNAL OF IMMUNOLOGY. Bd. 184. H. 7. 2010 S. 3964-3977


Kurschus, FC; Croxford, AL; Heinen, AP et al.

Genetic proof for the transient nature of the Th17 phenotype

EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 40. H. 12. 2010 S. 3336-3346


Riol-Blanco, L; Lazarevic, V; Awasthi, A et al.

IL-23 Receptor Regulates Unconventional IL-17-Producing T Cells That Control Bacterial Infections

JOURNAL OF IMMUNOLOGY. Bd. 184. H. 4. 2010 S. 1710-1720


Hesse, A; Wagner, M; Held, J et al.

In toxic demyelination oligodendroglial cell death occurs early and is FAS independent

NEUROBIOLOGY OF DISEASE. Bd. 37. H. 2. 2010 S. 362-369


Goetz, M; Ziebart, A; Foersch, S et al.

In Vivo Molecular Imaging of Colorectal Cancer With Confocal Endomicroscopy by Targeting Epidermal Growth Factor Receptor

GASTROENTEROLOGY. Bd. 138. H. 2. 2010 S. 435-446


Knorr, M; Hausding, M; Schuhmacher, S et al.

Lysozyme-M Positive Myelomonocytic cells Mediate Angiotensin-II induced Arterial Hypertension

FREE RADICAL BIOLOGY AND MEDICINE. Bd. 49. 2010 S. S24-S24


Lucas, T; Waisman, A; Krieg, T et al.

Macrophages as sentinels directing the quality of skin repair

JOURNAL OF INVESTIGATIVE DERMATOLOGY. Bd. 130. 2010 S. S35-S35


Foersch, S; Kiesslich, R; Waldner, MJ et al.

Molecular imaging of VEGF in gastrointestinal cancer in vivo using confocal laser endomicroscopy

GUT. Bd. 59. H. 8. 2010 S. 1046-1055


Atreya, R; Waldner, MJ; Neurath, MF

Molecular Imaging: Interaction Between Basic and Clinical Science

GASTROENTEROLOGY CLINICS OF NORTH AMERICA. Bd. 39. H. 4. 2010 S. 911-+


Bros, M; Dexheimer, N; Besche, V et al.

Mutated cylindromatosis gene affects the functional state of dendritic cells

EUROPEAN JOURNAL OF IMMUNOLOGY. Bd. 40. H. 10. 2010 S. 2848-2857


Mc Guire, C; Volckaert, T; Wolke, U et al.

Oligodendrocyte-Specific FADD Deletion Protects Mice from Autoimmune-Mediated Demyelination

JOURNAL OF IMMUNOLOGY. Bd. 185. H. 12. 2010 S. 7646-7653



Waldner, MJ; Wirtz, S; Becker, C et al.

Perforin Deficiency Attenuates Inflammation and Tumor Growth in Colitis-Associated Cancer

INFLAMMATORY BOWEL DISEASES. Bd. 16. H. 4. 2010 S. 559-567


Scholten, J; Gerbaulet, A; Hiller, B et al.

Skin mast cell populations do not recover in adult mice after induced ablation of mature mast cells but return under inflammatory conditions

EXPERIMENTAL DERMATOLOGY. Bd. 19. H. 2. 2010 S. 189-189



Waldner, MJ; Neurath, MF

The molecular therapy of colorectal cancer

MOLECULAR ASPECTS OF MEDICINE. Bd. 31. H. 2. 2010 S. 171-178


Boucheron, N; Sharif, O; Schebesta, A et al.

The Protein Tyrosine Kinase Tec Regulates a CD44(high) CD62L(-) Th17 Subset

JOURNAL OF IMMUNOLOGY. Bd. 185. H. 9. 2010 S. 5111-5119


Holtmann, MH; Barreiros, AP; Mudter, J et al.

Ultrasound Education by Simulator Training - Analysis of the Largest Simulator-Based Training in Germany

ZEITSCHRIFT FUR GASTROENTEROLOGIE. Bd. 48. H. 11. 2010 S. 1279-1284


Waldner, MJ; Wirtz, S; Jefremow, A et al.

VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer

JOURNAL OF EXPERIMENTAL MEDICINE. Bd. 207. H. 13. 2010 S. 2855-2868


Atreya, I; Diall, A; Ostrau, C et al.

Development and In Vivo Analysis of a New Generation of Optimized Thio-GTP Analogues for Therapy of IBD

GASTROENTEROLOGY. Bd. 136. H. 5. 2009 S. A406-A406


Neufert, C; Becker, C; Galle, PR et al.

Differential Expression Analysis of Colitis Associated Cancers

GASTROENTEROLOGY. Bd. 136. H. 5. 2009 S. A197-A197


Foersch, S; Kiesslich, R; Waldner, M et al.

In Vivo Molecular Imaging of VEGF in Gastrointestinal Cancer Using Confocal Laser Endomicroscopy

GASTROINTESTINAL ENDOSCOPY. Bd. 69. H. 5. 2009 S. AB130-AB130


Mudter, J; Yu, J; Amoussina, L et al.

IRF4 selectively controls cytokine gene expression in chronic intestinal inflammation

Arch Immunol Ther Exp (Warsz). Bd. 57. H. 5. 2009 S. 369-76


Srokowski, CC; Masri, J; Hövelmeyer, N et al.

Naturally occurring short splice variant of CYLD positively regulates dendritic cell function

Blood. Bd. 113. H. 23. 2009 S. 5891-5



Leppkes, M; Becker, C; Ivanov, II et al.

ROR gamma-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F

GASTROENTEROLOGY. Bd. 136. H. 1. 2009 S. 257-267


Weigmann, B; Neurath, MF

Selective targeting of activated T cells in chronic intestinal inflammation

Gut. Bd. 58. H. 6. 2009 S. 747-8


Fantini, MC; Rio, A; Fina, D et al.

Smad7 Controls Resistance of Colitogenic T Cells to Regulatory T Cell-Mediated Suppression

GASTROENTEROLOGY. Bd. 136. H. 4. 2009 S. 1308-1316


Fantini, MC; Rizzo, A; Fina, D et al.

Smad7 Expression in T Cells Protects from Colitis-Associated Colorectal Cancer

GASTROENTEROLOGY. Bd. 136. H. 5. 2009 S. A8-A9


Pickert, G; Neufert, C; Leppkes, M et al.

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

JOURNAL OF EXPERIMENTAL MEDICINE. Bd. 206. H. 7. 2009 S. 1465-1472


Pickert, G; Neufert, C; Leppkes, M et al.

STAT3 Links IL-22 Signalling in Intestinal Epithelial Cells to Mucosal Wound Healing

GASTROENTEROLOGY. Bd. 136. H. 5. 2009 S. A700-A700


Waldner, M; Wirtz, SJ; Neurath, MF

Targeting Angiogenesis in Colitis-Associated Cancer

GASTROENTEROLOGY. Bd. 136. H. 5. 2009 S. A464-A464


Weigmann, B; Lehr, HA; Galle, PR et al.

The Transcription Factor NFATC2 Controls Apoptosis and Activation of T Cells By IL-6 in Colitis

GASTROENTEROLOGY. Bd. 136. H. 5. 2009 S. A151-A151