Klinik und Poliklinik für Urologie und Kinderurologie
Klinikum / Johannes Gutenberg-Universität Mainz
Forschungsprojekte
Ergebnisse pro Seite:
100
2021 - 2022
Novel natural substances from the Baka ethnobotanical empirical knowledge for the management of urological cancers- PD Dr. Dr. EvaJüngel
2021 - 2022
The impact of shikonin combination therapy on the development of therapy resistance in advanced renal cell carcinoma- PD Dr. Dr. EvaJüngel
2021 - 2022
Growth behavior of bladder cancer after combined application with cisplatin and artesunat- PD Dr. Dr. EvaJüngel
2021 - 2023
Stellenwert der HDAC-Inhibition für die Therapie des fortgeschrittenen Peniskarzinoms- IgorTsaur
2021 - 2024
Impact of cholesterol- and lipid-homeostasis in patients with advanced and pre-treated prostate cancer (Palltur)- MaximilianBrandt
2021 - 2022
Evaluation der Sexualfunktion und Lebensqualität bei weiblichen Patienten nach Zystektomie und Harnableitung- PD Dr. ReneMager,
- PD Dr. SebastianFrees
2021 - 2025
BAY 88-8223 / 20510 RADIANT- Dr. MaximilianBrandt,
- PD Dr. MatthiasMiederer,
- Dr. StephanieNeuberger
2020 - 2022
Biomarker Prostata Evaluation neuer Biomarker beim Prostatakarzinom- Prof. Dr. IgorTsaur,
- PD Dr. KatharinaBöhm,
- Dr. AnitaThomas
2020 - 2023
BAY 20321 An open-label, single arm, roll-over study to provide continued treatment with darolutamide in participants who were enrolled in previous Bayer-sponsored studies- Prof. Dr. IgorTsaur,
- PD Dr. KatharinaBöhm,
- Dr. MaximilianBrandt
2020 - 2023
Exelixis CL184-313- PD Dr. ReneMager,
- Dr. StephanieNeuberger,
- Dr. MaximilianBrandt,
- PD Dr. KatharinaBöhm,
- PD Dr. ThomasHöfner
2020 - 2022
AR-assistierte MRT/TRUS-Fusionsbiopsie der Prostata- PD Dr. HendrikBorgmann,
- PeterSparwasser
2020 - 2022
Outcome of transperitoneal versus retroperitoneal robot assisted partial nephrectomy (TRAREN trial)- PD Dr. ReneMager
2020 - 2022
Comparative assessment of multi-tract versus single-tract percutaneous nephrolithotomy- PD Dr. ReneMager
2020 - 2022
The impact of artesunate on the matastatic behaviour of parental and cisplatin-resistant bladder cancer cells- PD Dr. Dr. EvaJüngel
2020 - 2022
Shikonin, a new compound to combate the growth of therapy-resistant renal cell carcinoma?- PD Dr. Dr. EvaJuengel
2020 - 2022
Evaluation the antitumoral efficacy of Shikonin on the mestastatic spread of therapy-resistant renal cell carcinoma in vitro- PD Dr. Dr. EvaJüngel
2019 - 2025
BMS CA17-078: A Phase 3, Randomized, Study of Neoadjuvant Chemotherapy alone versus Neoadjuvant Chemotherapy plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Post-Surgery Therapy with Nivolumab or Nivolumab and BMS-986205 in Participants with Muscle Invasive Bladder Cancer- Prof. Dr. IgorTsaur,
- PD Dr. ThomasHöfner,
- PD Dr. WolfgangJäger
2019 - 2021
Does artesunate induce cell death in docetaxel-resistant prostate carcinoma?- PD Dr. Dr. EvaJüngel
2019 - 2021
Artesunates impact on the progressive growth behavior of therapy-sensitive and cisplatin-resistant bladder cancer cells- PD Dr. Dr. EvaJüngel
2018 - 2021
The impact of artesunate on docetaxel-resistant prostate carcinoma in vitro- PD Dr. EvaJüngel
2018 - 2020
Prospective Registry for Patients Undergoing Surgery for Male Stress Urinary Incontinence in Multiple European Centres (SATURN)- RizwanHamid,
- Dr. TanjaHüsch
2018 - 2020
Comparison between artificial urinary sphincter and adjustable male sling in the treatment of moderate male urinary stress incontinence (AUSTIN)- Univ.-Prof. Dr. AxelHaferkamp,
- Dr. AxelKretschmer,
- Dr. MartinKurosch
2018 - 2020
INCB 54828-201: A Phase 2, Open-label, Single Agent, Multi-Center Study to Evaluate the Efficacy and Safety of a Pan-FGFR Tyrosine Kinase Inhibitor INCB054828 in Patients with Metastatic or Surgically Unresectable Urothelial Carcinoma Harboring FGF/FGFR Alterations- Prof. Dr. IgorTsaur,
- PD Dr. ThomasHöfner,
- PD Dr. WolfgangJäger
2018 - 2019
FORT-1:Phase 2/3 study of rogaratinib (BAY 1163877) vs chemotherapy in patients with FGFR-positive locally advanced or metastatic urothelial carcinoma- Prof. Dr. GeorgBartsch,
- Prof. Dr. IgorTsaur,
- PD Dr. ThomasHöfner
2018 - 2022
FORT-2: Phase 1b/2 study of rogaratinib (BAY 1163877) in combination with atezolizumab in urothelial carcinoma- Prof. Dr. GeorgBartsch,
- Prof. Dr. IgorTsaur,
- PD Dr. ThomasHöfner
2018 - 2022
Comparison of the genomic nanostructure of therapy-sensitive versus cisplatin-resistant bladder cancer cells- PD Dr. Dr. EvaJüngel
2018 - 2022
The relevance of the Akt/mTOR pathway in the pathogenesis of penile cancer- Prof. Dr. IgorTsaur,
- PD Dr. Dr. EvaJüngel
2018 - 2022
Integrin receptors – a therapeutic target for therapy resistant prostate carcinoma?- Prof. Dr. IgorTsaur,
- PD Dr. Dr. EvaJüngel (Mitverantwortliche Person)
2017 - 2023
MK3475-564: A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Pembrolizumab (MK-3475) as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post- PD Dr. ThomasHöfner,
- Dr. MaximilianBrandt,
- PD Dr. ReneMager
2017 - 2020
Influence of the plant Aristolochia clematitis on the incidence of urothelial carcinoma of upper urinary tract in Germany- Dr. MaximilianBrandt
2017 - 2019
The significance of the natural substance shikonin in the therapy of taxane-resistant prostate carcinoma- PD Dr. EvaJüngel
2017 - 2018
The significance of STAT5 on the growth and invasion of docetaxel-resistant prostate carcinomas- PD Dr. EvaJüngel
2016 - 2018
Assessment of E3 SUMO ligase PIAS1 as possible therapeutic target for urothelial carcinoma- Dr. HolgerErb,
- PD Dr. EvaJüngel
2016 - 2018
Significance of transcription factors in the resistance development of prostate carcinoma under antiandrogen therapy- Prof. Dr. ChristianThomas
2016 - 2018
Influence of miR143/145 cluster on prostate carcinoma therapy- Dr. HolgerErb,
- Prof. Dr. Norman JMaitland
2016 - 2018
Preclinical studies on the significance of mistletoe (Iscucin®) preparations in the therapy of urological tumors- PD Dr. EvaJüngel
2016 - 2017
Comparison of Twitter Activity for Prostate Cancer and Breast Cancer- Dr. HendrickBorgmann,
- Prof. Dr. StacyLoeb
2016 - 2017
Mapping the Landscape of Urology: A New Media-Based Cross-Sectional Analysis of Public Versus Academic Interest- Dr. HendrickBorgmann,
- Dr. JohannesSalem,
- PD Dr. JohannesHuber
2016 - 2018
Functional significance of sE-Cadherin for the tumorigenic properties of taxan-resistant prostate carcinoma cells- Prof. Dr. IgorTsaur
2016 - 2020
Urology Tag Ontology Project: Standardizing Social Media Communication- Dr. HendrickBorgmann,
- Prof. Dr. AlexanderKutikov
2015 - 2018
Prognostic Significance of Fuhrman Grade and Age for Cancer-Specific and Overall Survival in Patients with Papillary Renal Cell Carcinoma: Results of an International Multi-Institutional Study on 2189 Patients- Dr. HendrickBorgmann,
- PD Dr. SabineBrookman-May
2015 - 2016
ERA 223 Bayer 15396- PD Dr. WolfgangJäger,
- PD Dr. MatthiasMiederer,
- Univ.-Prof. Dr. MathiasSchreckenberger
2015 - 2018
Tumor immune escape mechanisms for therapy-resistant renal cell carcinoma- PD Dr. EvaJüngel
2015 - 2016
Protein Kinase C als zentraler Regulator der Progression des Nierenzellkarzioms und als potentielles therapeutisches Ziel- Prof. Dr. WalburgisBrenner
2015 - 2018
A Randomized, Open Label, Multicenter Study of Cabazitaxel Versus an Androgen Receptor (AR)-Targeted Agent (Abiraterone or Enzalutamide) in mCRPC Patients Previously Treated With Docetaxel and Who Rapidly Failed a Prior AR-targeted Agent (CARD)- Prof. Dr. ChristianThomas,
- Prof. Dr. IgorTsaur,
- PD Dr. WolfgangJäger,
- PD Dr. ThomasHöfner
2015 - 2016
Bedeutung des Tumorsuppressor-Proteins PTEN und seiner Splicevariante PTENdelta für die Karzinogenese und Metastasierung- Prof. Dr. WalburgisBrenner
2014 - 2017
Influence of AR-V7 expression in circulating tumor cells on therapy response in mCRPC patients- Prof. Dr. ChristianThomas
2014 - 2022
A multicenter, randomized, double-blind, placebo-controlled, phase III study of ARN-509 in men with non-metastatic (M0) castration-resistant prostate cancer (SPARTAN)- Prof. Dr. IgorTsaur,
- Dr. ThomasHöfner
2014 - 2015
Erythropoietin accelerates the regeneration of ureteral function in a murine model of obstructive uropathy- Dr. ClaudiaJanssen
2014 - 2017
Detection of circulating tumor cells and -DNA (CTC, ctDNA) via the androgen receptor AR-V7 in mCRPC- PD Dr. ChristianThomas
2014 - 2015
Herstellung prävaskularisierter Mundschleimhautäquivalente mittels Tissue-Engineering als intelligente Wundabdeckung bzw. zur Geweberekonstruktion in der regenerativen Medizin- Prof. Dr. JürgenBrieger,
- Prof. Dr. WalburgisBrenner
2013 - 2016
Bedeutung des Tumorsuppressor-Proteins PTEN für die Karzinogenese von Nierentumoren- Prof. Dr. WBrenner
2013 - 2018
Role of Hedgehog signalling as predictor of the oncologic outcome in renal cell carcinoma- Dr. WolfgangJäger,
- Prof. Dr. Peter C.Black