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Publikationen
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Pautz, A; Linker, K; Altenhöfer, S et al.

Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1.

J Biol Chem. Bd. 284. H. 5. 2009 S. 2755-66


Xia, N; Daiber, A; Habermeier, A et al.

SIRT1 as a regulator of cardiovascular oxidative stress

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 379. 2009 S. 21-22


Xia, N; Daiber, A; Habermeier, A et al.

SIRT1-Dependent and -Independent Effects of Resveratrol on Cardiovascular Oxidative Stress

CIRCULATION. Bd. 120. H. 18. 2009 S. S1085-S1085


Xia, N; Förstermann, U; Li, H

Sirt1-dependent and -independent effects of resveratrol on endothelial oxidative stress

Deutsche Gesellschaft für Arterioskleroseforschung (Hrsg). Inflammation, lipids and immunologic reactions during atherogenesis. Mannheim: Burger-Mannheim 2009


Art, J; Pautz, A; Schmidt, N et al.

The mRNA-binding protein KSRP regulates pro-inflammatory gene expression in human chondrocytes

Naunyn Schmiedebergs Arch Pharmacol. Bd. 379. 2009 S. R39


Wenzel, P; Schuhmacher, S; Schulz, E et al.

The organic nitrate pentaerithrityl tetranitrate improves vascular oxidative stress and dysfunction in experimental hypertension

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 379. 2009 S. 22-22


Bros, M; Wiechmann, N; Besche, V et al.

The RNA binding protein tristetraprolin influences the activation state of murine dendritic cells

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 379. 2009 S. 39-39


Zibat, A; Uhmann, A; Nitzki, F et al.

Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts.

Carcinogenesis. Bd. 30. H. 6. 2009 S. 918-26


Yan, T; Deng, S; Metzger, A et al.

Topoisomerase II alpha-dependent and -independent apoptotic effects of dexrazoxane and doxorubicin.

Mol Cancer Ther. Bd. 8. 2009 S. 1075-85




Kulle, B; Frigessi, A; Edvardsen, H et al.

Accounting for haplotype phase uncertainty in linkage disequilibrium estimation.

Genet Epidemiol. Bd. 32. H. 2. 2008 S. 168-78


Wenzel, P; Müller, J; Zurmeyer, S et al.

ALDH-2 deficiency increases cardiovascular oxidative stress – Evidence for indirect antioxidative properties

Biochem Biophys Res Commun. Bd. 367. 2008 S. 137-143



Heinrich, UR; Fischer, I; Brieger, J et al.

Ascorbic acid reduces noise-induced nitric oxide production in the guinea pig ear

Laryngoscope. Bd. 118. H. 5. 2008 S. 837-842


Wenzel, P; Schulz, E; Oelze, M et al.

AT(1)-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats

Free Radic Biol Med. Bd. 45. H. 5. 2008 S. 619-26


Tsukamoto, H; Irie, A; Senju, S et al.

B-Raf-mediated signaling pathway regulates T cell development.

Eur J Immunol. Bd. 38. H. 2. 2008 S. 518-27


Li, H; Steinkamp-Fenske, K; Bollinger, L et al.

Bedeutung vaskulaerer NADPH-Oxidasen fuer die Regulation der eNOS-Funktionalitaet

Herz. Bd. 33. 2008 S. 28-30 Suppl. II


Kassner, N; Huse, K; Martin, HJ et al.

Carbonyl reductase 1 is a predominant doxorubicin reductase in the human liver.

Drug Metab Dispos. Bd. 36. H. 10. 2008 S. 2113-20



Qiu, H; Taudien, S; Herlyn, H et al.

CYP3 phylogenomics: evidence for positive selection of CYP3A4 and CYP3A7.

Pharmacogenet Genomics. Bd. 18. H. 1. 2008 S. 53-66


Xu, H; Goettsch, C; Xia, N et al.

Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells.

Free Radic Biol Med. Bd. 44. H. 8. 2008 S. 1656-67




Heinrich, UR; Helling, K; Sifferath, M et al.

Gentamicin increases nitric oxide production and induces hearing loss in guinea pigs

Laryngoscope. Bd. 188. 2008 S. 1438 - 1442


Rodriguez-Pascual, F; Redondo-Horcajo, M; Magan-Marchal, N et al.

Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability.

Mol Cell Biol. Bd. 28. H. 23. 2008 S. 7139-55


Holden, M; Deng, S; Wojnowski, L et al.

GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies.

Bioinformatics. Bd. 24. H. 23. 2008 S. 2784-5



Barilli, A; Visigalli, R; Sala, R et al.

In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function.

Cardiovasc Res. Bd. 78. H. 3. 2008 S. 563-71


Elzner, S; Schmidt, D; Schollmeyer, D et al.

Inhibitors of inducible NO synthase expression: total synthesis of (S)-curvularin and its ring homologues.

ChemMedChem. Bd. 3. H. 6. 2008 S. 924-39



Engels, K; Knauer, SK; Loibl, S et al.

NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas

Cancer Res. Bd. 68. H. 13. 2008 S. 5159-66


Förstermann, U

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies.

Nat Clin Pract Cardiovasc Med. Bd. 5. H. 6. 2008 S. 338-49





Gradhand, U; Lang, T; Schaeffeler, E et al.

Variability in human hepatic MRP4 expression: influence of cholestasis and genotype.

Pharmacogenomics J. Bd. 8. H. 1. 2008 S. 42-52


Rotmann, A; Simon, A; Martine, U et al.

Activation of classical protein kinase C decreases transport via systems y+ and y+L.

Am J Physiol Cell Physiol. Bd. 292. H. 6. 2007 S. C2259-68


Mitchell, BM; Wallerath, T; Förstermann, U

Animal models of hypertension.

Methods Mol Med. Bd. 139. 2007 S. 105-11


Paulides, M; Wojnowski, L

Chemotherapeutikainduzierte Herzinsuffizienz.

Med Klin (Munich). Bd. 102. H. 7. 2007 S. 574-8


Torzewski, M; Ochsenhirt, V; Kleschyov, AL et al.

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

Arterioscler Thromb Vasc Biol. Bd. 27. H. 4. 2007 S. 850-7


Barbaux, S; Poirier, O; Godefroy, T et al.

Differential haplotypic expression of the interleukin-18 gene.

Eur J Hum Genet. Bd. 15. H. 8. 2007 S. 856-63


Traupe, T; Stettler, CD; Li, H et al.

Distinct roles of estrogen receptors alpha and beta mediating acute vasodilation of epicardial coronary arteries.

Hypertension. Bd. 49. H. 6. 2007 S. 1364-70


Wessler, I; Hölper, B; Kortsik, C et al.

Dysfunctional inhibitory muscarinic receptors mediate enhanced histamine release in isolated human bronchi

Life Sci. Bd. 80. H. 24-25. 2007 S. 2294-7


Deng, S; Kulle, B; Hosseini, M et al.

Dystrophin-deficiency increases the susceptibility to doxorubicin-induced cardiotoxicity.

Eur J Heart Fail. Bd. 9. H. 10. 2007 S. 986-94


Fischbach, T; Greffrath, W; Nawrath, H et al.

Effects of Anandamide and Noxious Heat on Intracellular Calcium Concentration in Nociceptive DRG Neurons of Rats.

J Neurophysiol. Bd. 98. H. 2. 2007 S. 929-38


Deng, S; Wojnowski, L

Genotyping the risk of anthracycline-induced cardiotoxicity.

Cardiovasc Toxicol. Bd. 7. H. 2. 2007 S. 129-34


Deng, S; Kruger, A; Kleschyov, AL et al.

Gp91phox-containing NAD(P)H oxidase increases superoxide formation by doxorubicin and NADPH.

Free Radic Biol Med. Bd. 42. H. 4. 2007 S. 466-73


Wenzel, P; Oelze, M; Coldewey, M et al.

Heme oxygenase-1: a novel key player in the development of tolerance in response to organic nitrates.

Arterioscler Thromb Vasc Biol. Bd. 27. H. 8. 2007 S. 1729-35


Nitzki, F; Kruger, A; Reifenberg, K et al.

Identification of a genetic contamination in a commercial mouse strain using two panels of polymorphic markers.

Lab Anim. Bd. 41. H. 2. 2007 S. 218-28


Alemdaroglu, NC; Wolffram, S; Boissel, JP et al.

Inhibition of folic acid uptake by catechins and tea extracts in Caco-2 cells.

Planta Med. Bd. 73. H. 1. 2007 S. 27-32


Reifenberg, K; Lehr, HA; Torzewski, M et al.

Interferon-gamma induces chronic active myocarditis and cardiomyopathy in transgenic mice.

Am J Pathol. Bd. 171. H. 2. 2007 S. 463-72


Schneider, G; Paus, TC; Kullak-Ublick, GA et al.

Linkage between a new splicing site mutation in the MDR3 alias ABCB4 gene and intrahepatic cholestasis of pregnancy.

Hepatology. Bd. 45. H. 1. 2007 S. 150-8


Peivandi, AA; Kayhan, N; Huhn, A et al.

mRNA and protein expression of phospholipases D1 and D2 increase in cardiac hypertrophy induced in the rat in vivo

Thorac Cardiovasc Surg. Bd. 1. 2007 S. 1



Cronauer, MV; Ince, Y; Engers, R et al.

Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression.

Oncogene. Bd. 26. H. 13. 2007 S. 1875-84


Glube, N; Closs, EI; Langguth, P

OCTN2-mediated carnitine uptake in a newly discovered human proximal tubule cell line (Caki-1).

Mol Pharm. Bd. 4. H. 1. 2007 S. 160-8


Horke, S; Witte, I; Wilgenbus, P et al.

Paraoxonase-2 reduces oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation.

Circulation. Bd. 115. H. 15. 2007 S. 2055-64



Korhonen, R; Linker, K; Pautz, A et al.

Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase.

Mol Pharmacol. Bd. 71. H. 5. 2007 S. 1427-34


Visigalli, R; Barilli, A; Bussolati, O et al.

Rapamycin stimulates arginine influx through CAT2 transporters in human endothelial cells.

Biochim Biophys Acta. Bd. 1768. H. 6. 2007 S. 1479-87


Steinkamp-Fenske, K; Bollinger, L; Xu, H et al.

Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells.

J Pharmacol Exp Ther. Bd. 322. H. 2. 2007 S. 836-42


Klein, T; Shephard, P; Kleinert, H et al.

Regulation of cyclooxygenase-2 expression by cyclic AMP.

Biochim Biophys Acta. Bd. 1773. H. 11. 2007 S. 1605-18


Santos, MI; Fuchs, S; Gomes, ME et al.

Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering

Biomaterials. Bd. 28. H. 2. 2007 S. 240-248


Schirmer, M; Rosenberger, A; Klein, K et al.

Sex-dependent genetic markers of CYP3A4 expression and activity in human liver microsomes.

Pharmacogenomics. Bd. 8. H. 5. 2007 S. 443-453



Ziesche, E; Bachmann, M; Kleinert, H et al.

The Interleukin-22/STAT3 Pathway Potentiates Expression of Inducible Nitric-oxide Synthase in Human Colon Carcinoma Cells.

J Biol Chem. Bd. 282. H. 22. 2007 S. 16006-15


Bros, M; Boissel, JP; Godtel-Armbrust, U et al.

The untranslated region of exon 2 of the human neuronal nitric oxide synthase (NOS1) gene exerts regulatory activity.

Gene. Bd. 405. H. 1-2. 2007 S. 36-46


Steinkamp-Fenske, K; Bollinger, L; Völler, N et al.

Ursolic acid from the Chinese herb danshen (Salvia miltiorrhiza L.) upregulates eNOS and downregulates Nox4 expression in human endothelial cells.

Atherosclerosis. Bd. 195. H. 1. 2007 S. e104-11


Gödtel-Armbrust, U; Metzger, A; Kroll, U et al.

Variability in PXR-mediated induction of CYP3A4 by commercial preparations and dry extracts of St. John's wort.

Naunyn Schmiedebergs Arch Pharmacol. Bd. 375. H. 6. 2007 S. 377-82



Wojnowski, L

ADHD drugs and cardiovascular risk

N Engl J Med. Bd. 354. H. 21. 2006 S. 2296-8; author reply 2296-8


Niemi, M; Arnold, KA; Backman, JT et al.

Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics.

Pharmacogenet Genomics. Bd. 16. H. 11. 2006 S. 801-8


Wojnowski, L; Kamdem, LK

Clinical implications of CYP3A polymorphisms.

Expert Opin Drug Metab Toxicol. Bd. 2. H. 2. 2006 S. 171-82


Pommerening, K; Muscholl, M

Datenschutz und Datensicherheit

B. Herbig, A. Büssing (Hrsg). Informations- und Kommunikationstechnologien im Krankenhaus. Stuttgart: Schattauer Verlag 2006


Kamdem, LK; Meineke, I; Gödtel-Armbrust, U et al.

Dominant contribution of P450 3A4 to the hepatic carcinogenic activation of aflatoxin B1.

Chem Res Toxicol. Bd. 19. H. 4. 2006 S. 577-86


Förstermann, U; Münzel, T

Endothelial nitric oxide synthase in vascular disease: from marvel to menace.

Circulation. Bd. 113. H. 13. 2006 S. 1708-14


Geber, C; Mang, CF; Kilbinger, H

Facilitation and inhibition by capsaicin of cholinergic neurotransmission in the guinea-pig small intestine.

Naunyn Schmiedebergs Arch Pharmacol. Bd. 372. H. 4. 2006 S. 277-83


Schirmer, M; Toliat, MR; Haberl, M et al.

Genetic signature consistent with selection against the CYP3A4*1B allele in non-African populations.

Pharmacogenet Genomics. Bd. 16. H. 1. 2006 S. 59-71


Lang, T; Haberl, M; Jung, D et al.

Genetic variability, haplotype structures, and ethnical diversity of hepatic transporters MDR3 (ABCB4) and BSEP (ABCB11).

Drug Metab Dispos. Bd. 34. H. 9. 2006 S. 1582-1599


Martin, L; Comalada, M; Marti, L et al.

Granulocyte-macrophage colony-stimulating factor increases L-arginine transport through the induction of CAT2 in bone marrow-derived macrophages.

Am J Physiol Cell Physiol. Bd. 290. H. 5. 2006 S. C1364-72


Gerber, S; Krasky, A; Rohwer, A et al.

Identification and characterisation of the dopamine receptor II from the cat flea Ctenocephalides felis (CfDopRII).

Insect Biochem Mol Biol. Bd. 36. H. 10. 2006 S. 749-58


Schlereth, T; Birklein, F; an Haack, K et al.

In vivo release of non-neuronal acetylcholine from the human skin as measured by dermal microdialysis: effect of botulinum toxin.

Br J Pharmacol. Bd. 147. H. 2. 2006 S. 183-7



Köhler, SC; Von Ahsen, N; Schlumbohm, C et al.

Marmoset CYP3A21, a model for human CYP3A4: protein expression and functional characterization of the promoter.

Xenobiotica. Bd. 36. H. 12. 2006 S. 1210-26



Oelze, M; Daiber, A; Brandes, RP et al.

Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.

Hypertension. Bd. 48. H. 4. 2006 S. 677-84


Bhattacharyya, SN; Habermacher, R; Martine, U et al.

Relief of microRNA-mediated translational repression in human cells subjected to stress.

Cell. Bd. 125. H. 6. 2006 S. 1111-24



Bhattacharyya, SN; Habermacher, R; Martine, U et al.

Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells.

Cold Spring Harb Symp Quant Biol. Bd. 71. 2006 S. 513-21


Closs, EI; Boissel, JP; Habermeier, A et al.

Structure and Function of Cationic Amino Acid Transporters (CATs).

J Membr Biol. Bd. 213. H. 2. 2006 S. 67-77



Kersting, G; Tzvetkov, MV; Huse, K et al.

Topoisomerase II beta expression level correlates with doxorubicin-induced apoptosis in peripheral blood cells.

Naunyn Schmiedebergs Arch Pharmacol. Bd. 374. H. 1. 2006 S. 21-30



Closs, EI; Leibach, F

Transport of peptides, amino acids, and derivatives

Amino Acids. Bd. 31. H. 2. 2006 S. 91