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Structural and Functional Characterisation of Amphibian Constitutive Androstane ReceptorNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 385. 2012 S. 65-65
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Successful Pharmacologic Treatment of Major Depressive Disorder Attenuates Amygdala Activation to Negative Facial Expressions: A Functional Magnetic Resonance Imaging StudyJOURNAL OF CLINICAL PSYCHIATRY. Bd. 73. H. 4. 2012 S. 451-459
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The Anti-Inflammatory Fungal Compound (S)-Curvularin Reduces Proinflammatory Gene Expression in an In Vivo Model of Rheumatoid ArthritisJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. Bd. 343. H. 1. 2012 S. 106-114
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The beta-3 adrenoceptor agonist solabegron is safe and effective for improving symptoms of overactive bladderEUROPEAN UROLOGY SUPPLEMENTS. Bd. 11. H. 1. 2012 S. E685-U462
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The Effect of Elective Sham Dose Escalation on the Placebo Response During an Antimuscarinic Trial for Overactive Bladder SymptomsJOURNAL OF UROLOGY. Bd. 187. H. 5. 2012 S. 1721-1726
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The Erk1/2-pathway is involved in PKC-induced Nox4 up-regulationNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 385. 2012 S. 82-83
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Transcriptional regulation of Nox4 by histone deacetylasesNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 385. 2012 S. 91-91
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Transcriptional regulation of Nox4 by histone deacetylases in human endothelial cellsBASIC RESEARCH IN CARDIOLOGY. Bd. 107. H. 5. 2012 S. -
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Transient receptor potential vanilloid 1 mediates nerve growth factor-induced bladder hyperactivity and noxious inputBJU INTERNATIONAL. Bd. 110. H. 8B. 2012 S. E422-E428
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Unexpected frequent hepatotoxicity of a prescription drug, flupirtine, marketed for about 30 yearsBRITISH JOURNAL OF CLINICAL PHARMACOLOGY. Bd. 73. H. 5. 2012 S. 821-825
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ASSESSMENT OF ENDOPLASMIC RETICULUM STRESS AND THE UNFOLDED PROTEIN RESPONSE IN ENDOTHELIAL CELLSMethods in Enzymology. Bd. 489. 2011 S. 127-146
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AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive ratsBRITISH JOURNAL OF PHARMACOLOGY. Bd. 163. H. 5. 2011 S. 1078-1085
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Betulinic acid protects against cerebral ischemia-reperfusion injury in mice by reducing oxidative and nitrosative stressNITRIC OXIDE-BIOLOGY AND CHEMISTRY. Bd. 24. H. 3. 2011 S. 132-138
Witte, I; Altenhofer, S; Wilgenbus, P et al.
Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cellsCELL DEATH & DISEASE. Bd. 2. 2011 S. -
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Characterization of the xeno-/endobiotic sensor CAR in all classes of land vertebratesNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 44-44
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Dexmethasone upregulates Nox1 expression in vascular smooth muscle cellsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 43-43
Jaenecke, I; Boissel, JP; Gasnier, B et al.
Do SLC7 family members constitute the lysosomal transport system c?NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 40-40
Helling, K; Wodarzcyk, K; Brieger, J et al.
Doxycycline reduces nitric oxide production in guinea pig inner earsAURIS NASUS LARYNX. Bd. 38. H. 6. 2011 S. 671-677
Arlanov, R; Porter, A; Strand, D et al.
FUNCTIONAL COMPARISON OF NATURAL VARIANTS OF THE ABC MEMBRANE TRANSPORTER MRP2 USING A TARGETED EXPRESSION SYSTEM IN HUMAN FIBROSARCOMA CELLSBRITISH JOURNAL OF CLINICAL PHARMACOLOGY. Bd. 72. 2011 S. 34-34
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Induction of tolerogenic lung CD4(+) T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthmaINTERNATIONAL IMMUNOLOGY. Bd. 23. H. 1. 2011 S. 1-15
Yan, T; Deng, S; Fuhrmann, D et al.
Mechanism of ATF3 Induction by dexrazoxane and its role in DNA repair and apoptosisNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 97-97
Tenzer, S; Docter, D; Rosfa, S et al.
Nanoparticle Size Is a Critical Physicochemical Determinant of the Human Blood Plasma Corona: A Comprehensive Quantitative Proteomic AnalysisACS NANO. Bd. 5. H. 9. 2011 S. 7155-7167
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Paraoxonase-1 and clopidogrel efficacyNATURE MEDICINE. Bd. 17. H. 9. 2011 S. 1041-1042
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Protein Kinase C-dependent Ubiquitination and Clathrin-mediated Endocytosis of the Cationic Amino Acid Transporter CAT-1JOURNAL OF BIOLOGICAL CHEMISTRY. Bd. 286. H. 10. 2011 S. 8697-8706
Witte, I; Amort, J; Wilgenbus, P et al.
Pursuing redox balance: paraoxonase-2 as new putative anti-tumor targetNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 39-39
Oelze, M; Knorr, M; Schell, R et al.
Regulation of Human Mitochondrial Aldehyde Dehydrogenase (ALDH-2) Activity by Electrophiles in VitroJOURNAL OF BIOLOGICAL CHEMISTRY. Bd. 286. H. 11. 2011 S. 8893-8900
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Regulation of Nox1 expression by histone deacetylases in vascular smooth muscle cellsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 35-35
Karbach, S; Simon, A; Slenzka, A et al.
Relative contribution of different L-arginine sources to the substrate supply of endothelial nitric oxide synthaseJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. Bd. 51. H. 5. 2011 S. 855-861
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Removal of intracellular asymmetric dimethyl-L-arginine (ADMA) requires system y(+)L membrane transporter - despite significant activity of the metabolising enzyme dimethylarginine dimethylaminohydrolase (DDAH)NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 30-30
Forstermann, U
Research Oversight in Germany: Safeguards and ShortcomingsANESTHESIA AND ANALGESIA. Bd. 112. H. 3. 2011 S. 504-506
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S100A8 a new biomarker for chronic inflammatory diseases - gender specific expression in systemic lupus erythematosus?NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 30-30
Fusser, M; Nesse, GJ; Khobta, A et al.
Spontaneous mutagenesis in Csb(m/m)Ogg1(-/-) mice is attenuated by dietary resveratrolCARCINOGENESIS. Bd. 32. H. 1. 2011 S. 80-85
Forsch, I; Koch, K; Art, J et al.
The cytoplasmic poly(A) binding protein (PABP) post-transcriptionally regulates human iNOS expression - involvement of the 5 '-untranslated mRNA sequenceNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 32-33
Art, J; Schmidt, N; Forsch, I et al.
The mRNA binding protein KSRP is regulated in rheumatoid arthritisNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 44-44
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The persecution of pharmacologists in Nazi Germany and AustriaNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. H. 3. 2011 S. 217-225
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The role of RhoGTPase Cdc42 in regulation of arginine transport mediated by human cationic amino acid transporters (hCAT)NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 383. 2011 S. 31-31
Forstermann, U; Li, HG
Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncouplingBRITISH JOURNAL OF PHARMACOLOGY. Bd. 164. H. 2. 2011 S. 213-223
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Vascular Dysfunction in Experimental Diabetes Is Improved by Pentaerithrityl Tetranitrate but Not Isosorbide-5-Mononitrate TherapyDIABETES. Bd. 60. H. 10. 2011 S. 2608-2616
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A Functional Polymorphism in the NAD(P)H Oxidase Subunit CYBA Is Related to Gene Expression, Enzyme Activity, and Outcome in Non-Hodgkin LymphomaCANCER RESEARCH. Bd. 70. H. 6. 2010 S. 2328-2338
Zillessen, U; Li, H; Mildenberger, E
Expression of NO synthases and redox enzymes in umbilical arteries from newborns born small, appropriate, and large for gestational age [Abstract]Pediatr Res. Bd. 68. H. Spl1. 2010 S. 110-111
Arlanov, R; Porter, A; Brough, R et al.
GENERATING TETRACYCLINE INDUCIBLE MRP2 CELL-LINESBRITISH JOURNAL OF CLINICAL PHARMACOLOGY. Bd. 70. 2010 S. 7-7
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Gentamicin Alters Nitric Oxide Production in Semicircular Canals and Otolith OrgansLARYNGOSCOPE. Bd. 120. H. 10. 2010 S. 2125-2128
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Identification of proteins that bind and regulate the promoter of the multitasking human enzyme paraoxonase-2EUROPEAN JOURNAL OF CELL BIOLOGY. Bd. 89. 2010 S. 8-8
Amort, J; Wilgenbus, P; Buck, F et al.
Identification of proteins that bind and regulate the promoter of the multitasking human enzyme paraoxonase-2NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 22-22
Nem, D; Qiu, H; Nestler, S et al.
In vitro and in vivo analysis of the human cyp3a5 promoterNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 88-88
Pautz, A; Rauschkolb, P; Art, J et al.
Is the chronic inflammation in rheumatoid arthritis a trigger for the development of atherosclerosis?NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 38-38
Xia, N; Daiber, A; Habermeier, A et al.
Molecular mechanisms of the antioxidative effects of resveratrolNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 21-21
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Neuronal Nitric Oxide Synthase Modulates Maturation of Human Dendritic CellsJOURNAL OF IMMUNOLOGY. Bd. 184. H. 11. 2010 S. 6025-6034
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New role for an anti-atherosclerotic enzyme: PON2 confers apoptosis resistance and is overexpressed in tumorsEUROPEAN JOURNAL OF CELL BIOLOGY. Bd. 89. 2010 S. 57-58
Witte, I; Altenhofer, S; Wilgenbus, P et al.
New role for an anti-atherosclerotic enzyme: PON2 confers apoptosis resistance and is overexpressed in tumorsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 71-71
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Nitric oxide and oxidative stress in vascular diseasePFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. Bd. 459. H. 6. 2010 S. 923-939
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One Enzyme, Two Functions PON2 PREVENTS MITOCHONDRIAL SUPEROXIDE FORMATION AND APOPTOSIS INDEPENDENT FROM ITS LACTONASE ACTIVITYJOURNAL OF BIOLOGICAL CHEMISTRY. Bd. 285. H. 32. 2010 S. 24398-24403
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Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyaninBIOCHEMICAL JOURNAL. Bd. 426. 2010 S. 73-83
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Paraoxonase 2 is downregulated by the Pseudomonas aeruginosa quorum sensing signal N-(3-oxododecanoyl1)-L-homoserine lactone and attenuates oxidative stress induced by pyocyaninBiochem J. Bd. 1. 2010 S. 73-83
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Pentaerythritol Tetranitrate Improves Angiotensin II-Induced Vascular Dysfunction via Induction of Heme Oxygenase-1HYPERTENSION. Bd. 55. H. 4. 2010 S. 897-U153
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Pharmakologie von NO und der NitratePharmazie in unserer Zeit. Bd. 39. H. 5. 2010 S. 345-350
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Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide ProductionGASTROENTEROLOGY. Bd. 139. H. 5. 2010 S. 1686-+
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Post-transcriptional regulation of human iNOS expression by the cytoplasmic poly(A) binding protein (PABP)NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 19-19
Xia, N; Bollinger, L; Steinkamp-Fenske, K et al.
Prunella vulgaris L. Upregulates eNOS Expression in Human Endothelial CellsAMERICAN JOURNAL OF CHINESE MEDICINE. Bd. 38. H. 3. 2010 S. 599-611
Horke, S; Witte, I; Wilgenbus, P et al.
Redox and calcium warfare between Pseudomonas aeruginosa and human cells: it's about lactones, pyocyanin and paraoxonase-2NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 21-22
Voss, C; Pautz, A; Art, J et al.
Regulation of gene expression by organic nitratesNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 19-19
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Regulation of gene expression by organic nitratesHERZ. Bd. 35. 2010 S. 56-66
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Regulation of Human ALDH-2 Activity by Electrophiles - Implications for Organic Nitrate Induced Tolerance, Oxidative Stress and Reactive Fatty Acid Metabolites in MIFREE RADICAL BIOLOGY AND MEDICINE. Bd. 49. 2010 S. S102-S102
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Regulation of the expression of inducible nitric oxide synthaseNITRIC OXIDE-BIOLOGY AND CHEMISTRY. Bd. 23. H. 2. 2010 S. 75-93
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Resveratrol Reverses Endothelial Nitric-Oxide Synthase Uncoupling in Apolipoprotein E Knockout MiceJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. Bd. 335. H. 1. 2010 S. 149-154
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RESVERATROL REVERSES eNOS UNCOUPLING: IMPLICATION OF SIRT1ATHEROSCLEROSIS SUPPLEMENTS. Bd. 11. H. 2. 2010 S. 97-97
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Resveratrol: A Multifunctional Compound Improving Endothelial Function (vol 23, pg 425, 2009)CARDIOVASCULAR DRUGS AND THERAPY. Bd. 24. H. 1. 2010 S. 91-91
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Small molecules enhancing eNOS expression and activity, and preventing eNOS uncouplingNITRIC OXIDE-BIOLOGY AND CHEMISTRY. Bd. 22. 2010 S. S14-S14
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The bacterium Pseudomonas aeruginosa subverts our defense by inactivating paraoxonase-2: the search for post-translational modificationsNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 34-34
Qiu, H; Mathas, M; Godtel-Armbrust, U et al.
The identification of the constitutive androstane receptor (CAR) in all classes of tetrapodaNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 90-90
Bros, M; Wiechmann, N; Besche, V et al.
The RNA binding protein tristetraprolin influences the activation state of murine dendritic cellsMOLECULAR IMMUNOLOGY. Bd. 47. H. 5. 2010 S. 1161-1170
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The unique complexity of the CYP3A4 upstream region suggests a nongenetic explanation of its expression variabilityPHARMACOGENETICS AND GENOMICS. Bd. 20. H. 3. 2010 S. 167-178
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TOP2B contributes to doxorubicin-induced DNA damage and mediates protective effects of dexrazoxane against doxorubicin-induced cell toxicityNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 66-66
Deng, S; Yan, T; Godtel-Armbrust, U et al.
Topoisomerase II alpha-mediated repression of gene expression in response to doxorubicinNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 66-66
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Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytesBIOCHEMICAL PHARMACOLOGY. Bd. 79. H. 5. 2010 S. 722-732
Altenhofer, S; Witte, I; Wilgenbus, P et al.
Two functions of one enzyme: The lactonase activity of PON2 is independent from its anti-oxidative and anti-apoptotic roleEUROPEAN JOURNAL OF CELL BIOLOGY. Bd. 89. 2010 S. 5-5
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Two functions of one enzyme: the lactonase activity of PON2 is independent from its anti-oxidative and anti-apoptotic roleNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 381. 2010 S. 21-21
Daiber, A; Oelze, M; Kamuf, J et al.
Updates on antioxidant properties of PETN and nitrate metabolism in isolated ALDH-2HERZ. Bd. 35. 2010 S. 24-35
Ecke, I; Petry, F; Rosenberger, A et al.
Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice.Cancer Res. Bd. 69. H. 3. 2009 S. 887-95
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Arginine transport in human erythroid cells: discrimination of CAT1 and 4F2hc/y(+)LAT2 rolesPflugers Arch. 2009 S. 001
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AUF1 regulates human iNOS expression by modulation of mRNA stabilityNaunyn Schmiedebergs Arch Pharmacol. Bd. 379. 2009 S. R19
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Die Bedeutung des humanen Enzyms Paraoxonase-2 (PON2) als neues antioxidatives und antiapoptotisches System der GefäßwandHerz. Bd. 34. H. (SII. 2009 S. 7-11
Deng, S; Kruger, A; Schmidt, A et al.
Differential roles of nitric oxide synthase isozymes in cardiotoxicity and mortality following chronic doxorubicin treatment in mice.Naunyn Schmiedebergs Arch Pharmacol. Bd. 380. H. 1. 2009 S. 25-34
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Effects of betulinic acid in a rat model of cerebral venous ischemiaJOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. Bd. 29. 2009 S. S224-S225
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Effects of nitroglycerin or pentaerithrityl tetranitrate treatment on the gene expression in rat hearts: evidence for cardiotoxic and cardioprotective effectsPHYSIOLOGICAL GENOMICS. Bd. 38. H. 2. 2009 S. 176-185
Daiber, A; Kamuf, J; Pautz, A et al.
Effects of Pentaerithrityl Tetranitrate and Glyceryl Trinitrate on Activity of Purified Human Mitochondrial Aldehyde DehydrogenaseFREE RADICAL BIOLOGY AND MEDICINE. Bd. 47. 2009 S. S73-S73
Kleinert, H; Daiber, A; Pautz, A et al.
First results on the effects of a treatment with nitroglycerin (NTG) and pentaerithrityl tetranitrate (PETN) on the whole genome expression profile in cardiomyocytes - Is there evidence of "cardiotoxic" and "cardioprotective" mechanisms?HERZ. Bd. 34. 2009 S. 19-26
Huang, L; Li, Q; Li, H et al.
Inhibition of intracellular Ca2+ release by a Rho-kinase inhibitor for the treatment of ischemic damage in primary cultured rat hippocampal neurons.Eur J Pharmacol. Bd. 602. H. 2-3. 2009 S. 238-44
Kumar, S; Qiu, H; Oezguen, N et al.
Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection.Drug Metab Dispos. Bd. 37. H. 6. 2009 S. 1328-33
Simon, A; Graulich, E; Habermann, A et al.
Neuronal nitric oxide synthase is involved in maturation of human dendritic cells and induction of Th1 responsesEXPERIMENTAL DERMATOLOGY. Bd. 18. H. 3. 2009 S. 295-295
Huang, X; Li, Q; Li, H et al.
Neuroprotective and Antioxidative Effect of Cactus Polysaccharides In Vivo and In VitroCell Mol Neurobiol. Bd. 29. H. 8. 2009 S. 1211-1221
Huang, X; Li, Q; Li, H et al.
Neuroprotective and Antioxidative Effect of Cactus Polysaccharids In Vivo and in VitroCell Mol Neurobiol. Bd. 29. H. 8. 2009 S. 1211-1221
Scalera, F; Closs, EI; Flick, E et al.
Paradoxical effect of L-arginine: acceleration of endothelial cell senescence.Biochem Biophys Res Commun. Bd. 386. H. 4. 2009 S. 650-5
Li, H; Förstermann, U
Prevention of atherosclerosis by interference with the vascular nitric oxide system.Curr Pharm Des. Bd. 15. H. 27. 2009 S. 3133-45
Fischer, I; Heinrich, UR; Brieger, J et al.
Protektion der Kochlea durch Vitamin C bei LärmexpositionHNO. Bd. 57. 2009 S. 339 - 344
Stalleicken, D; Kleinert, H
Regulation der Regulation der Genexpression durch organische Nitrate - Evidenz für kardioprotektive Wirkungen von PETN?Perfusion. Bd. 22. 2009 S. 126-130
Spanier, G; Xu, H; Xia, N et al.
RESVERATROL REDUCES ENDOTHELIAL OXIDATIVE STRESS BY MODULATING THE GENE EXPRESSION OF SUPEROXIDE DISMUTASE 1 (SOD1), GLUTATHIONE PEROXIDASE 1 (GPX1) AND NADPH OXIDASE SUBUNIT (NOX4)JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. Bd. 60. 2009 S. 111-116
Li, H; Forstermann, U
Resveratrol: A Multifunctional Compound Improving Endothelial FunctionCARDIOVASCULAR DRUGS AND THERAPY. Bd. 23. H. 6. 2009 S. 425-429
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S-Curvularin inhibits pro-inflammatory gene espression in different models of rhematoid arthritisNaunyn Schmiedebergs Arch Pharmacol. Bd. 379. 2009 S. R40
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S-Curvularin inhibits pro-inflammatory gene expression in different models of rheumatoid arthritisNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Bd. 379. 2009 S. 40-40