Institut für Physiologische Chemie und Pathobiochemie
Vorklinik / Johannes Gutenberg-Universität Mainz
Müller, WEG; Boreiko, A; Schloßmacher, U et al.
Identification of a silicatein(-related) protease in the giant spicules of the deep sea hexactinellid Monorhaphis chuniJ Exp Biol. Bd. 211. 2008 S. 300-309
Steiner, MA; Wanisch, K; Monory, K et al.
Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice.Pharmacogenomics J. Bd. 8. H. 3. 2008 S. 196-208
Waldron, E; Isbert, S; Kern, A et al.
Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcription.Exp Cell Res. Bd. 314. H. 13. 2008 S. 2419-33
Izzo, AA; Aviello, G; Petrosino, S et al.
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.J Mol Med. Bd. 86. H. 1. 2008 S. 89-98
Czirr, E; Cottrell, BA; Leuchtenberger, S et al.
Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase.J Biol Chem. Bd. 283. H. 25. 2008 S. 17049-54
Müller, WEG
IntronEncyclopedia of Science and Technology. 10. Aufl. New York: McGraw Hill 2008
Bringmann, G; Mutanyatta-Comar, J; Maksimenka, K et al.
Joziknipholones A and B: The first dimeric phenylanthraquinones, from the roots of Bulbine frutescensChem Eur J (Chemistry). Bd. 14. 2008 S. 1420-1429
Tamboli, IY; Prager, K; Thal, DR et al.
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.J Neurosci. Bd. 28. H. 46. 2008 S. 12097-106
Bilbao, A; Parkitna, JR; Engblom, D et al.
Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine.Proc Natl Acad Sci U S A. Bd. 105. H. 45. 2008 S. 17549-54
Waldron, Elaine; Heilig, Catherine; Schweitzer, Andrea et al.
Lrp1 modulates app trafficking along early compartments of the secretory pathwayNeurobiology of disease. Bd. 31. H. 2. Amsterdam: Elsevier 2008 S. 188 - 197
Thakur, NL; Jain, R; Natalio, F et al.
Marine molecular biology: an emerging field of biological sciencesBiotechnol Adv. Bd. 26. 2008 S. 233-245
Lukić-Bilela, L; Brandt, D; Pojskić, N et al.
Mitochondrial genome of Suberites domuncula: palindromes and inverted repeats are abundant in non-coding regionsGene. Bd. 412. 2008 S. 1-11
Moosmann, B; Behl, C
Mitochondrially encoded cysteine predicts animal lifespan.Aging Cell. Bd. 7. H. 1. 2008 S. 32-46
Kaandorp, JA; Blom, JG; Verhoef, J et al.
Modelling genetic regulation of growth and form in a branching spongeProc Biol Sci. Bd. 275. 2008 S. 2569-2575
Behl, C; Moosmann, B
Molekulare Mechanismen des Alterns. Über das Altern der Zellen und den Einfluss von oxidativem Stress auf den AlternsprozessU.M. Staudinger, H. Häfner (Hrsg). Was ist Alter(n)? Neue Antworten auf eine scheinbar einfache Frage. [Schriften der Mathematisch-naturwissenschaftlichen Klasse der Heidelberger Akademie der Wissenschaften, Nr. 18, 2008]. Berlin Heidelberg: Springer 2008
Behl, C
Morbus Alzheimer und weitere neurodegenerative ErkrankungenF. Holsboer, G. Gründer, O. Benkert (Hrsg). Handbuch der Psychopharmakotherapie. Heidelberg: Springer Medizin Verlag 2008
Shukoor, MI; Natalio, F; Tahir, MN et al.
Multifunctional polymer-derivatized γ-Fe2O3 nanocrystals as a methodology for the biomagnetic separation of recombinant His-tagged proteinsJ Magn Magn Mater. Bd. 320. 2008 S. 2339-2344
Jeong, WI; Osei-Hyiaman, D; Park, O et al.
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver.Cell Metab. Bd. 7. H. 3. 2008 S. 227-35
Müller, WEG; Schloßmacher, U; Wang, X et al.
Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica-polymerase and silica-esterase)FEBS J. Bd. 275. 2008 S. 362-370
Moreira, FA; Kaiser, N; Monory, K et al.
Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors.Neuropharmacology. Bd. 54. H. 1. 2008 S. 141-50
Wiens, M; Belikov, SI; Kaluzhanya, OV et al.
Regional and modular expression of morphogenetic factors in the demosponge Lubomirskia baicalensisMicron. Bd. 39. 2008 S. 447-460
Müller, WEG; Wang, X; Kropf, K et al.
Silicatein expression in the hexactinellid Crateromorpha meyeri: the lead marker gene restricted to siliceous spongesCell Tissue Res. Bd. 333. 2008 S. 339-351
Lutz, B; Monory, K
Soothing the seizures of children.Nat Med. Bd. 14. H. 7. 2008 S. 721-2
Proksch, P; Ebel, R; Edrada, RA et al.
Sponge-associated fungi and their bioactive compounds: the Suberites caseBotanica Marina. Bd. 51. 2008 S. 209-218
Storr, MA; Keenan, CM; Emmerdinger, D et al.
Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors.J Mol Med. Bd. 86. H. 8. 2008 S. 925-36
Klugmann, M; Szumlinski, KK
Targeting Homer genes using adeno-associated viral vector: lessons learned from behavioural and neurochemical studies.Behav Pharmacol. Bd. 19. H. 5-6. 2008 S. 485-500
Schröder, HC; Natalio, F; Wiens, M et al.
The 2'-5'-oligoadenylate synthetase in the lowest metazoa: isolation, cloning, expression and functional activity in the sponge Lubomirskia baicalensisMol Immunol. Bd. 45. 2008 S. 945-953
Sitz, JH; Baumgartel, K; Hammerle, B et al.
The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4.Neuroscience. Bd. 157. H. 3. 2008 S. 596-605
Moreira, FA; Lutz, B
The endocannabinoid system: emotion, learning and addiction.Addict Biol. Bd. 13. H. 2. 2008 S. 196-212
Martin, Anne M.; Kuhlmann, Christoph; Trossbach, Svenja et al.
The functional role of the second npxy motif of the lrp1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-d-aspartate receptorsJournal of biological chemistry. Bd. 283. H. 18. Bethesda, Md.: ASBMB 2008 S. 12004 - 12013
Hanstein, R; Lu, A; Wurst, W et al.
Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress.Neuroscience. Bd. 156. H. 3. 2008 S. 712-21
Price, DA; Seillier, A; Koek, W et al.
WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cellEur J Neurosci. Bd. 29. 2008 S. 2177-86
Schneider, M; Spanagel, R; Zhang, SJ et al.
Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice.BMC Neurosci. Bd. 8. 2007 S. 105
Wilkesman, J; Schröder, HC
Analysis of serine proteases from marine sponges by 2-D zymographyElectrophoresis. Bd. 28. 2007 S. 429-436
Müller, WEG; Schlossmacher, U; Eckert, C et al.
Analysis of the axial filament in spicules of the demosponge Geodia cydonium: Different silicatein composition in microscleres (asters) and megascleres (oxeas and triaenes)Eur J Cell Biol. Bd. 86. 2007 S. 473-487
Müller, WEG; Li, J; Schröder, HC et al.
b) The unique skeleton of siliceous sponges (Porifera; Hexactinellida and Demospongiae) that evolved first from the Urmetazoa during the Proterozoic: a review.Biogeosciences. Bd. 4. 2007 S. 219-232
Yuece, B; Sibaev, A; Broedl, UC et al.
Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex.Neurogastroenterol Motil. Bd. 19. H. 9. 2007 S. 744-53
Agarwal, N; Pacher, P; Tegeder, I et al.
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.Nat Neurosci. Bd. 10. 2007 S. 870-9
Tremel, W; Shukoor, MI; Natalio, F et al.
Cell Specific Targeting of Multifunctional γ-Fe2O3 Nanoparticles Through Surface Binding of dsRNAMater Res Soc Symp Proc. Bd. 1088. 2007 S. I15-05
Gamerdinger, M; Clement, AB; Behl, C
Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-beta production.Mol Pharmacol. Bd. 72. H. 1. 2007 S. 141-51
Müller, WEG; Belikov, SI; Kaluzhnaya, OV et al.
Cold stress defense in the freshwater sponge Lubomirskia baicalensis. Role of okadaic acid produced by symbiotic dinoflagellates.FEBS J. Bd. 274. 2007 S. 23-36
Aiello, A; Fattorusso, E; Giordano, A et al.
Damipipecolin and damituricin, novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella damicornis.Bioorg Med Chem. Bd. 15. 2007 S. 5877-5887
Brenz Verca, MS; Weber, P; Mayer, C et al.
Development of a species-specific RNA polymerase I-based shRNA expression vector.Nucleic Acids Res. Bd. 35. H. 2. 2007 S. 10
Maresz, K; Pryce, G; Ponomarev, ED et al.
Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells.Nat Med. Bd. 13. H. 4. 2007 S. 492-7
Finkenwirth, C; Schröder, HC; Roßbach, B et al.
DNA integrity in lymphocytes from subjects exposed to ozone in vivo determined by fast micromethodNaunyn Schmiedebergs Arch Pharmacol. Bd. 375. H. 1. 2007 S. 101
Shukoor, MI; Natalio, F; Ksenofontov, V et al.
Double-stranded RNA polyinosinic-polycytidylic acid immobilized onto gamma-Fe2O3 nanoparticles by using a multifunctional polymeric linker.Small. Bd. 3. 2007 S. 1374-1378
Schroder, JE; Tegeler, MR; Grosshans, U et al.
Dystroglycan regulates structure, proliferation and differentiation of neuroepithelial cells in the developing vertebrate CNS.Dev Biol. Bd. 307. H. 1. 2007 S. 62-78
Schröder, HC; Brandt, D; Schlossmacher, U et al.
Enzymatic production of biosilica glass using enzymes from sponges: basic aspects and application in nanobiotechnology (material sciences and medicine).Naturwissenschaften. Bd. 94. 2007 S. 339-359
Moser, N; Mechawar, N; Jones, I et al.
Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures.J Neurochem. Bd. 102. H. 2. 2007 S. 479-92
Müller, WEG; Eckert, C; Kropf, K et al.
Formation of giant spicules in the deep-sea hexactinellid Monorhaphis chuni (Schulze 1904): electron-microscopic and biochemical studies.Cell Tissue Res. Bd. 329. 2007 S. 363-378