Inhaltszusammenfassung

The vinylogous addition of deprotonated N-alkyl-alpha-aminonitriles to alpha,beta-unsaturated carbonyl compounds yields cyclic intermediates which can be reduced to form polysubstituted pyrrolidines in a one-pot reaction sequence. Since the cyano substituent is lost in the reduction step, the aminonitriles serve as easily accessible (N-alkylamino)-substituted carbanion equivalents.

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Klassifikation

DDC Sachgruppe:
Chemie