Facile preparation of 3-amino-4-(arylamino)-1h-isochromen-1-ones by a new multicomponent reaction
European journal of organic chemistry. Bd. 2005. H. 5. Weinheim: Wiley-VCH 2005 S. 817 - 821
Erscheinungsjahr: 2005
ISBN/ISSN: 1434-193X
Publikationstyp: Zeitschriftenaufsatz
Sprache: Englisch
Doi/URN: 10.1002/ejoc.200400685
| Geprüft: | Bibliothek |
Inhaltszusammenfassung
Reactions between 2-formylbenzoic acid, various anilines and HCN result in the formation of 3-amino-4-(arylamino)-1H-isochromen-1-ones in high yield. The mechanism of this three-component condensation involves the intermediate formation of an alpha-aminonitrile and subsequent cyclizationthrough nucleophilic attack of the ortho-carboxylate at the nitrile carbon. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005).
Autoren
Opatz, Till (Autor)
Ferenc, D. (Autor)
Klassifikation
DDC Sachgruppe:
Chemie
