Randomised, double blind, multicentre comparison of hydrochlorothiazide, atenolol, nitrendipine, and enalapril in antihypertensive treatment: results of the HANE study
British medical journal. Bd. 315. H. 7101. London: Assoc 1997 S. 154 - 159
Erscheinungsjahr: 1997
ISBN/ISSN: 0959-8138
Publikationstyp: Zeitschriftenaufsatz
Sprache: Englisch
| Geprüft: | Bibliothek |
Inhaltszusammenfassung
Objective: To compare the effectiveness and tolerability of hydrochlorothiazide, atenolol, nitrendipine, and enalapril in patients with mild to moderate hypertension. Design: Randomised multicentre trial over 48 weeks with double blind comparison of treatments. Setting: 48 centres in four countries. Patients: 868 patients with essential hypertension (diastolic blood pressure 95-120 mm Hg). Interventions: Initial treatment (step 1) consisted of 12.5 mg hydrochlorothiazide (n=215), 25 mg atenol...Objective: To compare the effectiveness and tolerability of hydrochlorothiazide, atenolol, nitrendipine, and enalapril in patients with mild to moderate hypertension. Design: Randomised multicentre trial over 48 weeks with double blind comparison of treatments. Setting: 48 centres in four countries. Patients: 868 patients with essential hypertension (diastolic blood pressure 95-120 mm Hg). Interventions: Initial treatment (step 1) consisted of 12.5 mg hydrochlorothiazide (n=215), 25 mg atenolol (n=215), 10 mg nitrendipine (n=218), or 5 mg enalapril (n=220) once daily. If diastolic blood pressure was not reduced to » weiterlesen» einklappen
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Medizin
