IL-6 trans-signaling : the heat is on
Immunity. Bd. 20. H. 1. Cambridge, Mass.: Cell Press 2004 S. 2 - 4
Erscheinungsjahr: 2004
ISBN/ISSN: 1074-7613
Publikationstyp: Zeitschriftenaufsatz
Sprache: Englisch
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Inhaltszusammenfassung
The molecular consequence of the fever response has been illuminated by a recent study showing that a temperature shift to 40 degrees C resulted in increased leukocyte adhesion to tissue sections, which was mediated by L-selectin activation in lymphocytes. This L-selectin activation during heat responses was dependent on IL-6 trans-signaling via the soluble IL-6R.
Autoren
Rose-John, Stefan (Autor)
Neurath, Markus F. (Autor)
Klassifikation
DDC Sachgruppe:
Medizin