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Concepts for the treatment of alzheimer's disease : molecular mechanisms and clinical application

International journal of experimental pathology. Bd. 86. H. 3. Oxford: Blackwell 2005 S. 173 - 185

Erscheinungsjahr: 2005

ISBN/ISSN: 0959-9673

Publikationstyp: Zeitschriftenaufsatz

Sprache: Englisch

Doi/URN: 10.1111/j.0959-9673.2005.00435.x

Volltext über DOI/URN

Geprüft:Bibliothek

Inhaltszusammenfassung


To date, various strategies have been developed in order to prevent or to slow down the progression of Alzheimer's disease (AD). Despite the medical need for an effective therapeutic treatment of AD, progress towards this goal is painstakingly slow. Although AD is the most common neurodegenerative disorder and a large amount of primary basic and clinical research has been performed already, it appears very difficult to identify appropriate targets, which would promise fast, effective and safe...To date, various strategies have been developed in order to prevent or to slow down the progression of Alzheimer's disease (AD). Despite the medical need for an effective therapeutic treatment of AD, progress towards this goal is painstakingly slow. Although AD is the most common neurodegenerative disorder and a large amount of primary basic and clinical research has been performed already, it appears very difficult to identify appropriate targets, which would promise fast, effective and safe strategies to combat the disease onset and progression. In this review, we present some of clinically applied treatment options, which may improve AD symptoms for a short period but so far lack the ability to prevent or halt this devastating disease. Additionally, we summarize some of the experimental approaches in AD therapy, which might lead to the development of more promising drugs in the future.» weiterlesen» einklappen

Autoren


Pietrzik, Claus (Autor)
Behl, Christian (Autor)

Klassifikation


DDC Sachgruppe:
Medizin